AU2889097A - Identification of members of combinatorial libraries by mass spectrometry - Google Patents

Identification of members of combinatorial libraries by mass spectrometry

Info

Publication number
AU2889097A
AU2889097A AU28890/97A AU2889097A AU2889097A AU 2889097 A AU2889097 A AU 2889097A AU 28890/97 A AU28890/97 A AU 28890/97A AU 2889097 A AU2889097 A AU 2889097A AU 2889097 A AU2889097 A AU 2889097A
Authority
AU
Australia
Prior art keywords
identification
members
mass spectrometry
combinatorial libraries
combinatorial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU28890/97A
Inventor
Christine Goeller
Michele Ann Kelly
Hongbin Liang
Hans Mathis Thoma
Lawrence Paul Wennogle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG, Novartis AG filed Critical Ciba Geigy AG
Publication of AU2889097A publication Critical patent/AU2889097A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AU28890/97A 1996-05-10 1997-04-30 Identification of members of combinatorial libraries by mass spectrometry Abandoned AU2889097A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1754596P 1996-05-10 1996-05-10
US60017545 1996-05-10
PCT/EP1997/002215 WO1997043301A2 (en) 1996-05-10 1997-04-30 Identification of members of combinatorial libraries by mass spectrometry

Publications (1)

Publication Number Publication Date
AU2889097A true AU2889097A (en) 1997-12-05

Family

ID=21783193

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28890/97A Abandoned AU2889097A (en) 1996-05-10 1997-04-30 Identification of members of combinatorial libraries by mass spectrometry

Country Status (3)

Country Link
AU (1) AU2889097A (en)
WO (1) WO1997043301A2 (en)
ZA (1) ZA974027B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6720190B1 (en) 1998-03-27 2004-04-13 Ole Hindsgaul Methods for screening compound libraries
CA2240325A1 (en) * 1998-03-27 1998-11-14 Synsorb Biotech, Inc. Methods for screening compound libraries
US6054047A (en) 1998-03-27 2000-04-25 Synsorb Biotech, Inc. Apparatus for screening compound libraries
US6191418B1 (en) * 1998-03-27 2001-02-20 Synsorb Biotech, Inc. Device for delivery of multiple liquid sample streams to a mass spectrometer
US6613575B1 (en) 1998-03-27 2003-09-02 Ole Hindsgaul Methods for screening compound libraries
EP1048950A1 (en) * 1999-04-26 2000-11-02 ScreenTec B.V. Identification of ligands for orphan receptors using on-line coupling of mass spectrometry to continuous-flow separation techniques
DE19943743C2 (en) * 1999-09-03 2002-02-07 Jerini Biotools Gmbh Procedure for the identification of binding partners with position-specific arrays
AU2001278872A1 (en) 2000-07-06 2002-01-21 Genvec, Inc. Method of identifying a binding partner of a gene product
EP1299950B1 (en) 2000-07-13 2008-05-21 CT-Concept Technologie AG Method and device for a condition-dependent control of the transient behavior of power semiconductor switches
AU2001284867A1 (en) 2000-08-14 2002-02-25 Surface Logix, Inc. Biomolecule arrays
DE10125258A1 (en) * 2001-05-23 2003-01-09 November Ag Molekulare Medizin Method for determining the binding behavior of ligands that specifically bind to target molecules
EP1916521A4 (en) * 2005-07-29 2011-01-05 Eisai R&D Man Co Ltd Method for analysis of compound-binding ability of protein
US20100227414A1 (en) * 2009-03-05 2010-09-09 Trex Enterprises Corp. Affinity capture mass spectroscopy with a porous silicon biosensor
BR112015013525A2 (en) 2012-12-10 2017-11-14 Hutchinson Fred Cancer Res a method for producing a fusion protein as well as a composition comprising a fusion protein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532167A (en) * 1994-01-07 1996-07-02 Beth Israel Hospital Substrate specificity of protein kinases
WO1995025737A1 (en) * 1994-03-23 1995-09-28 The Penn State Research Foundation Method for identifying members of combinatorial libraries
US5891742A (en) * 1995-01-19 1999-04-06 Chiron Corporation Affinity selection of ligands by mass spectroscopy
GB9507366D0 (en) * 1995-04-08 1995-05-31 Zeneca Ltd Assay

Also Published As

Publication number Publication date
WO1997043301A2 (en) 1997-11-20
WO1997043301A3 (en) 1998-02-19
ZA974027B (en) 1998-01-23

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