FI933165A - NYA FOSPHOLIPIDDERIVAT - Google Patents

NYA FOSPHOLIPIDDERIVAT Download PDF

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Publication number
FI933165A
FI933165A FI933165A FI933165A FI933165A FI 933165 A FI933165 A FI 933165A FI 933165 A FI933165 A FI 933165A FI 933165 A FI933165 A FI 933165A FI 933165 A FI933165 A FI 933165A
Authority
FI
Finland
Prior art keywords
fospholipidderivat
nya
medicaments
preparation processes
phospholipid derivatives
Prior art date
Application number
FI933165A
Other languages
Finnish (fi)
Other versions
FI111262B (en
FI933165A0 (en
Inventor
Gerhard Noessner
Bernhard Kutscher
Juergen Engel
Wolfgang Schumacher
Jurij Stekar
Peter Hilgard
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of FI933165A0 publication Critical patent/FI933165A0/en
Publication of FI933165A publication Critical patent/FI933165A/en
Application granted granted Critical
Publication of FI111262B publication Critical patent/FI111262B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/106—Adducts, complexes, salts of phosphatides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532—Seven-(or more) membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • AIDS & HIV (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel phospholipid derivatives, preparation processes therefor and their use as medicaments are described.
FI933165A 1992-07-11 1993-07-09 Process for the preparation of therapeutically useful phospholipid derivatives FI111262B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4222910 1992-07-11
DE4222910A DE4222910A1 (en) 1992-07-11 1992-07-11 New phospholipid derivatives

Publications (3)

Publication Number Publication Date
FI933165A0 FI933165A0 (en) 1993-07-09
FI933165A true FI933165A (en) 1994-01-12
FI111262B FI111262B (en) 2003-06-30

Family

ID=6463031

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933165A FI111262B (en) 1992-07-11 1993-07-09 Process for the preparation of therapeutically useful phospholipid derivatives

Country Status (31)

Country Link
EP (1) EP0579939B1 (en)
JP (1) JP3311431B2 (en)
KR (1) KR100297180B1 (en)
CN (1) CN1039012C (en)
AT (1) ATE176477T1 (en)
AU (1) AU664101B2 (en)
BR (1) BR9302809A (en)
CA (2) CA2100228C (en)
CZ (1) CZ290863B6 (en)
DE (2) DE4222910A1 (en)
DK (1) DK0579939T3 (en)
EE (1) EE03140B1 (en)
ES (1) ES2129053T3 (en)
FI (1) FI111262B (en)
GR (1) GR3029602T3 (en)
HR (1) HRP931046B1 (en)
HU (1) HU218783B (en)
IL (1) IL106289A (en)
LT (1) LT3113B (en)
LV (1) LV10870B (en)
MX (1) MX9304133A (en)
NO (1) NO306468B1 (en)
PL (3) PL177811B1 (en)
RU (1) RU2108336C1 (en)
SG (1) SG46249A1 (en)
SI (1) SI9300365B (en)
SK (1) SK283827B6 (en)
TW (1) TW304956B (en)
UA (1) UA40567C2 (en)
YU (1) YU49079B (en)
ZA (1) ZA934971B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5475234B2 (en) 2005-01-21 2014-04-16 アステックス・セラピューティクス・リミテッド Pharmaceutical compounds
JP5232009B2 (en) * 2005-12-19 2013-07-10 エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング Alkyl phospholipid derivatives having reduced cytotoxicity and uses thereof
EP1800684A1 (en) * 2005-12-20 2007-06-27 Zentaris GmbH Novel alkyl phospholipid derivatives and uses thereof
EP1869981A1 (en) * 2006-06-21 2007-12-26 Staatliches Weinbauinstitut Freiburg Alkylphospholipids and lysophospholipids for controlling plant pathogens
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444766A (en) * 1980-10-21 1984-04-24 Boehringer Mannheim Gmbh Sulfur-containing phospholipid compounds and therapeutic compositions
JPS5984824A (en) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd Antitumor agent
DE3530767A1 (en) * 1985-08-28 1987-03-12 Max Planck Gesellschaft AGENT AGAINST MULTIPLE Sclerosis
CA1280369C (en) * 1985-12-04 1991-02-19 Hansjorg Eibl Pharmaceutical with anti-tumor effect
JP2512311B2 (en) * 1986-07-14 1996-07-03 日本ケミファ株式会社 Novel glycerin derivative and antihypertensive agent
US4962096A (en) * 1987-03-24 1990-10-09 Nippon Chemiphar Co., Ltd. Heterocyclic glycerol derivatives and their use as anti-hypertensive agents
DE3906952A1 (en) * 1989-03-04 1990-09-06 Boehringer Mannheim Gmbh (3- (C (DOWN ARROW)) (DOWN ARROW) (DOWN ARROW) 6 (DOWN ARROW) -C (DOWN ARROW) 1 (DOWN ARROW) (DOWN ARROW) 8 (DOWN ARROW)) ALKANSULFINYL AND 2 SULPHONE -METHOXYMETHYL-PROPYL) - (2-TRIMETHYLAMMONIO-ETHYL) PHOSPHATES, METHOD FOR PRODUCING THE MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3942933A1 (en) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh USE OF ALKYLPHOSPHOLIPIDES AS ANTIVIRAL MEDICINAL PRODUCTS AND NEW PHOSPHOLIPID DERIVATIVES
DE4114586A1 (en) * 1991-05-04 1992-11-05 Boehringer Mannheim Gmbh MEDICINAL PRODUCTS CONTAINING AZACYCLODIPHOSPHONIC ACID DERIVATIVES, NEW AZACYCLODIPHOSPHONIC ACID DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF

Also Published As

Publication number Publication date
BR9302809A (en) 1994-03-15
IL106289A0 (en) 1994-04-12
DK0579939T3 (en) 1999-09-20
DE4222910A1 (en) 1994-01-13
CA2100228A1 (en) 1994-01-12
PL175607B1 (en) 1999-01-29
KR940002265A (en) 1994-02-17
YU47393A (en) 1997-08-22
IL106289A (en) 2000-06-01
NO932502L (en) 1994-01-12
FI111262B (en) 2003-06-30
YU49079B (en) 2003-08-29
HU218783B (en) 2000-12-28
HRP931046A2 (en) 1997-04-30
CZ290863B6 (en) 2002-11-13
AU664101B2 (en) 1995-11-02
CA2511753A1 (en) 1994-01-12
HUT64548A (en) 1994-01-28
AU4186493A (en) 1994-01-13
MX9304133A (en) 1994-04-29
PL299624A1 (en) 1994-02-21
FI933165A0 (en) 1993-07-09
HRP931046B1 (en) 2000-06-30
TW304956B (en) 1997-05-11
GR3029602T3 (en) 1999-06-30
LV10870A (en) 1995-10-20
SI9300365B (en) 2002-02-28
ZA934971B (en) 1994-02-01
DE59309355D1 (en) 1999-03-18
RU2108336C1 (en) 1998-04-10
EE03140B1 (en) 1998-12-15
LT3113B (en) 1994-12-27
PL173388B1 (en) 1998-02-27
SK67093A3 (en) 1995-03-08
EP0579939B1 (en) 1999-02-03
CZ124993A3 (en) 1995-03-15
HU9301992D0 (en) 1993-09-28
NO932502D0 (en) 1993-07-08
SI9300365A (en) 1994-03-31
ATE176477T1 (en) 1999-02-15
SG46249A1 (en) 1998-02-20
NO306468B1 (en) 1999-11-08
KR100297180B1 (en) 2001-11-30
PL177811B1 (en) 2000-01-31
CN1039012C (en) 1998-07-08
CA2511753C (en) 2007-09-25
LTIP620A (en) 1994-07-15
JP3311431B2 (en) 2002-08-05
ES2129053T3 (en) 1999-06-01
EP0579939A1 (en) 1994-01-26
SK283827B6 (en) 2004-02-03
UA40567C2 (en) 2001-08-15
CN1084175A (en) 1994-03-23
CA2100228C (en) 2006-01-24
JPH0733791A (en) 1995-02-03
LV10870B (en) 1996-06-20

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Owner name: AETERNA ZENTARIS GMBH

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