MY8100371A - 5-(2-foroyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo [1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof - Google Patents

5-(2-foroyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo [1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof

Info

Publication number: MY8100371A
Authority: MY; Malaysia
Prior art keywords: thenoyl; foroyl; furoyl; pyrrolo; pyrrole
Prior art date: 1976-07-14

Application number

MY371/81A

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-07-14

Filing date

1981-12-30

Publication date

1981-12-31

1977-02-23 Priority claimed from US05/771,283 external-priority patent/US4087539A/en

1981-12-30 Application filed by Syntex Inc filed Critical Syntex Inc

1981-12-31 Publication of MY8100371A publication Critical patent/MY8100371A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

MY371/81A 1976-07-14 1981-12-30 5-(2-foroyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo [1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof MY8100371A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US70485776A	1976-07-14	1976-07-14
US05/771,283 US4087539A (en)	1976-07-14	1977-02-23	5-(2-Furoyl)-, 5-(2-thenoyl)-, 5-(3-furoyl)- and 5-(3-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof

Publications (1)

Publication Number	Publication Date
MY8100371A true MY8100371A (en)	1981-12-31

Family

ID=27107392

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MY371/81A MY8100371A (en)	1976-07-14	1981-12-30	5-(2-foroyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo [1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof

Country Status (26)

Country	Link
JP (1)	JPS539789A (en)
AR (1)	AR218631A1 (en)
AU (1)	AU513385B2 (en)
CA (1)	CA1100140A (en)
CH (2)	CH651045A5 (en)
CS (1)	CS208724B2 (en)
DE (1)	DE2731662A1 (en)
DK (1)	DK152652C (en)
ES (2)	ES460705A1 (en)
FI (1)	FI63407C (en)
FR (1)	FR2361396A1 (en)
GB (1)	GB1554076A (en)
GR (1)	GR61607B (en)
HK (1)	HK17581A (en)
IE (1)	IE45302B1 (en)
IL (1)	IL52492A (en)
IT (1)	IT1117314B (en)
MY (1)	MY8100371A (en)
NL (1)	NL7707652A (en)
NO (1)	NO147563C (en)
NZ (1)	NZ184611A (en)
PL (1)	PL111408B1 (en)
PT (1)	PT66779B (en)
SE (1)	SE434644B (en)
SU (2)	SU664566A3 (en)
YU (2)	YU43157B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4097579A (en) *	1977-03-31	1978-06-27	Syntex (U.S.A.) Inc.	5-(2-Pyrroyl)-1,2-dihydro-3H-pyrrolo 1,2-a!pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4140698A (en) *	1977-07-25	1979-02-20	Syntex (Usa) Inc.	1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
US4353829A (en) *	1980-11-21	1982-10-12	Syntex (U.S.A.) Inc.	Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
JPS5910589A (en) *	1982-06-10	1984-01-20	メルク　エンド　カムパニー　インコーポレーテツド	Antiinflammatory and analgesic novel 5-(pyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2-a) pyrrole derivative
US4511724A (en) *	1982-06-10	1985-04-16	Merck & Co., Inc.	5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
HU198927B (en) *	1987-01-14	1989-12-28	Richter Gedeon Vegyeszet	Process for producing 1-/substituted aminomethyl/-octa-hydroindolo-(2,3-a)quinolizine derivatives, pharmaceutically applicable acid addition salts thereof, as well as pharmaceutical compositions comprising same
US4874871A (en) *	1987-03-25	1989-10-17	Syntex (U.S.A.) Inc.	Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds

1977
- 1977-05-17 JP JP5697877A patent/JPS539789A/en active Granted
- 1977-07-07 GR GR53906A patent/GR61607B/en unknown
- 1977-07-07 AR AR268357A patent/AR218631A1/en active
- 1977-07-07 DK DK307677A patent/DK152652C/en not_active IP Right Cessation
- 1977-07-08 CH CH4005/84A patent/CH651045A5/en not_active IP Right Cessation
- 1977-07-08 NL NL7707652A patent/NL7707652A/en not_active Application Discontinuation
- 1977-07-08 IL IL52492A patent/IL52492A/en unknown
- 1977-07-08 CH CH848877A patent/CH644861A5/en not_active IP Right Cessation
- 1977-07-08 IE IE1422/77A patent/IE45302B1/en unknown
- 1977-07-08 PT PT66779A patent/PT66779B/en unknown
- 1977-07-11 GB GB28923/77A patent/GB1554076A/en not_active Expired
- 1977-07-11 FI FI772154A patent/FI63407C/en not_active IP Right Cessation
- 1977-07-11 NZ NZ184611A patent/NZ184611A/en unknown
- 1977-07-12 FR FR7721559A patent/FR2361396A1/en active Granted
- 1977-07-12 CS CS774647A patent/CS208724B2/en unknown
- 1977-07-12 CA CA282,600A patent/CA1100140A/en not_active Expired
- 1977-07-13 DE DE19772731662 patent/DE2731662A1/en active Granted
- 1977-07-13 AU AU26976/77A patent/AU513385B2/en not_active Expired
- 1977-07-13 SE SE7708142A patent/SE434644B/en not_active IP Right Cessation
- 1977-07-13 PL PL1977199602A patent/PL111408B1/en unknown
- 1977-07-13 NO NO772493A patent/NO147563C/en unknown
- 1977-07-13 ES ES460705A patent/ES460705A1/en not_active Expired
- 1977-07-13 SU SU772504151A patent/SU664566A3/en active
- 1977-07-13 IT IT68631/77A patent/IT1117314B/en active
- 1977-12-29 SU SU772558960A patent/SU793400A3/en active
1978
- 1978-05-24 ES ES470213A patent/ES470213A1/en not_active Expired
1981
- 1981-04-30 HK HK175/81A patent/HK17581A/en unknown
- 1981-12-30 MY MY371/81A patent/MY8100371A/en unknown
1983
- 1983-02-28 YU YU476/83A patent/YU43157B/en unknown
- 1983-02-28 YU YU475/83A patent/YU43156B/en unknown

Also Published As

Publication number	Publication date
CS208724B2 (en)	1981-09-15
PL111408B1 (en)	1980-08-30
CH651045A5 (en)	1985-08-30
FR2361396A1 (en)	1978-03-10
DE2731662A1 (en)	1978-01-19
NO147563C (en)	1983-05-18
PT66779A (en)	1977-08-01
SE434644B (en)	1984-08-06
JPS539789A (en)	1978-01-28
SU793400A3 (en)	1980-12-30
JPS6254110B2 (en)	1987-11-13
CH644861A5 (en)	1984-08-31
DK152652C (en)	1988-09-12
YU47683A (en)	1984-04-30
YU43156B (en)	1989-04-30
ES460705A1 (en)	1979-10-01
GB1554076A (en)	1979-10-17
FI63407B (en)	1983-02-28
DE2731662C2 (en)	1989-11-09
AR218631A1 (en)	1980-06-30
IE45302B1 (en)	1982-07-28
CA1100140A (en)	1981-04-28
YU47583A (en)	1984-06-30
NO147563B (en)	1983-01-24
DK152652B (en)	1988-04-05
NZ184611A (en)	1979-03-28
AU513385B2 (en)	1980-11-27
IL52492A (en)	1981-06-29
DK307677A (en)	1978-01-15
YU43157B (en)	1989-04-30
NL7707652A (en)	1978-01-17
IL52492A0 (en)	1977-10-31
HK17581A (en)	1981-05-08
IT1117314B (en)	1986-02-17
NO772493L (en)	1978-01-17
SU664566A3 (en)	1979-05-25
ES470213A1 (en)	1979-09-16
AU2697677A (en)	1979-01-18
PT66779B (en)	1978-12-18
FR2361396B1 (en)	1981-11-27
FI772154A (en)	1978-01-15
IE45302L (en)	1978-01-14
FI63407C (en)	1983-06-10
PL199602A1 (en)	1979-01-29
GR61607B (en)	1978-12-02
SE7708142L (en)	1978-01-15

Publication	Publication Date	Title
ZA774239B (en)	1979-02-28	5-(2-furoyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof
YU42163B (en)	1988-06-30	Process for obtaining derivatives 3-(1h-tetrazole-5-yl)-4h-pyrido(1,2-a)pyrimidin-4-ones
AU518169B2 (en)	1981-09-17	5-(2-PYRROLO-l, 2-DIHYDRO-3H-PYRROLO f 1 2-a 1 PYRROLE-1 CARBOXYLIC ACID DERIVATIVES
NO1994007I1 (en)	1994-07-29	Ketorolac / 5-benzoyl-1,2-dihydro-3H-pyrrolo- [1,2-a] pyrrole-1-carboxylic acid and its pharmaceutically acceptable salts
HU175537B (en)	1980-08-28	Process for producing new, pharmaceutically active pyrimidone derivatives containing heterocyclic substituent in the side chain
DE3869257D1 (en)	1992-04-23	N-AMINOBUTYL-N-PHENYLARYLAMIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE IN THE MEDICINE.
HK15981A (en)	1981-05-01	1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof
DE2860560D1 (en)	1981-04-16	5-substituted-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carbonitriles and process for their conversion to the corresponding 1-carboxylic acids
DE3377713D1 (en)	1988-09-22	New 5-(pyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole derivatives as anti-inflammatory and analgesic agents
MY8100371A (en)	1981-12-31	5-(2-foroyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo [1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof
HU173438B (en)	1979-05-28	Process for preparing new 4-oxo-1,6,7,8-tetrahydro-4h-pyrido-/1,2-a/pyrimidine derivatives with antiinflammatory and anticoagulant activity
DE3865073D1 (en)	1991-10-31	IMIDAZOPYRIDINE DERIVATIVES, THEIR PRODUCTION AND THERAPEUTIC USE.
NL7708543A (en)	1978-02-15	PROCESS FOR PREPARING 5-AMINO-1,2,3-THIAZIA DIOLA AND ITS DERIVATIVES.
MTP811B (en)	1978-02-20	Indolo (3,2,1-de)(1.5) naphthyzidine derivatives
NO801376L (en)	1980-11-12	PROCEDURE FOR PREPARING 3-SUBSTITUTED TETRAHYDRO-PYRROLO (1,2-A) PYRIMIDINE DERIVATIVES
HRP940490B1 (en)	1996-06-30	5-AROYL-1,2-DIHYDRO-3H-PYRROLO(1,2-a)PYRROLE-1-CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THE PRODUCTION THEREOF
DE3580773D1 (en)	1991-01-17	IMIDAZO (1,5-A) PYRIDYL-METHANE AND IMIDAZO (1,5-B) PYRIDAZINYL-METHANE DERIVATIVES, THEIR PRODUCTION AND THE RECORDING MATERIALS CONTAINING THEM.
AU493450B2 (en)	1977-09-29	Diazolo, diazino and diazepino [1,2-a] otrudi azeoube derivatives
AU513384C (en)	1992-07-09	5-aroyl-l., 2-dihydro-3H-pyrrolo(1, 2-a) pyrrole 1-carboxylic acid derivatives
HU175301B (en)	1980-06-28	Process for preparing 5-substituted 1,2-dihydro-3h-pyrrolo/1,2-a/-pyrrol-1-carboxylic acid derivatives
AU1236176A (en)	1977-09-29	Diazolo, diazino and diazepino [1,2-a] otrudi azeoube derivatives