NO962186D0 - Method of preparing combinatorial connection libraries - Google Patents

Method of preparing combinatorial connection libraries

Info

Publication number
NO962186D0
NO962186D0 NO962186A NO962186A NO962186D0 NO 962186 D0 NO962186 D0 NO 962186D0 NO 962186 A NO962186 A NO 962186A NO 962186 A NO962186 A NO 962186A NO 962186 D0 NO962186 D0 NO 962186D0
Authority
NO
Norway
Prior art keywords
preparing combinatorial
combinatorial connection
connection libraries
libraries
preparing
Prior art date
Application number
NO962186A
Other languages
Norwegian (no)
Other versions
NO962186L (en
Inventor
Eduard Felder
Hans Rink
Ian Timothy William Matthews
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO962186L publication Critical patent/NO962186L/en
Publication of NO962186D0 publication Critical patent/NO962186D0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047Simultaneous synthesis of different peptide species; Peptide libraries
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811Selection methods for production or design of target specific oligonucleotides or binding molecules
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845Methods of identifying protein-protein interactions in protein mixtures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/005Beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572Chemical means
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO962186A 1993-12-09 1996-05-29 Method of preparing combinatorial connection libraries NO962186D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93810864 1993-12-09
PCT/EP1994/003936 WO1995016209A1 (en) 1993-12-09 1994-11-28 Process for the production of combinatorial compound libraries

Publications (2)

Publication Number Publication Date
NO962186L NO962186L (en) 1996-05-29
NO962186D0 true NO962186D0 (en) 1996-05-29

Family

ID=8215084

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962186A NO962186D0 (en) 1993-12-09 1996-05-29 Method of preparing combinatorial connection libraries

Country Status (9)

Country Link
EP (1) EP0733213A1 (en)
JP (1) JPH09508355A (en)
AU (1) AU1068295A (en)
CA (1) CA2175078A1 (en)
FI (1) FI962371A0 (en)
HU (1) HUT75223A (en)
IL (1) IL111906A0 (en)
NO (1) NO962186D0 (en)
WO (1) WO1995016209A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5110096A (en) * 1995-03-28 1996-10-16 Novartis Ag Process for the production of combinatorial compound libraries
WO1997011958A1 (en) * 1995-09-29 1997-04-03 The Scripps Research Institute Protein signature analysis
US20030100007A1 (en) * 1995-12-18 2003-05-29 Howard Benjamin Methods for identifying compounds that bind to a target
US5866341A (en) * 1996-04-03 1999-02-02 Chugai Pharmaceutical Co., Ltd. Compositions and methods for screening drug libraries
EP2261335B1 (en) 1998-11-27 2017-06-14 UCB Pharma S.A. Compositions and methods for increasing bone mineralisation
US20040009535A1 (en) 1998-11-27 2004-01-15 Celltech R&D, Inc. Compositions and methods for increasing bone mineralization
CA2329016A1 (en) * 1999-02-17 2000-08-24 Arcaris, Inc. Methods for substrate-ligand interaction screening
AU772069B2 (en) * 1999-03-23 2004-04-08 Merck Patent Gesellschaft Mit Beschrankter Haftung Protein isolation and analysis
WO2000066259A1 (en) 1999-05-05 2000-11-09 Ut-Battelle, Llc Method and apparatus for combinatorial chemistry
US7351540B1 (en) 2000-03-17 2008-04-01 Merck Patent Gmbh Protein isolation and analysis
US20020106648A1 (en) * 2000-05-05 2002-08-08 Lizardi Paul M. Highly multiplexed reporter carrier systems
DE10117274B4 (en) * 2001-04-06 2005-03-03 Hte Ag The High Throughput Experimentation Company Method for analyzing and archiving at least one material library
EP1967525B1 (en) 2001-05-08 2012-11-14 Darwin Molecular Corporation A method for regulating immune function in primates using the foxp3 protein
JP2005514603A (en) * 2001-11-06 2005-05-19 アジリックス・コーポレイション High sensitivity coded detection system
EP2258724A1 (en) 2002-11-21 2010-12-08 Celltech R & D, Inc. Modulating immune responses using multimerized anti-CD83 antibodies
EP1731908B1 (en) 2004-03-31 2010-09-01 Kazuo Shinya Method of biosubstance trapping, structural analysis or/and identification with use of a labeling substance
US20240374761A1 (en) 2021-05-05 2024-11-14 Radius Pharmaceuticals, Inc. Animal model having homologous recombination of mouse pth1 receptor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK105289A (en) * 1988-03-04 1989-09-05 Univ Alabama PEPTIDA EQUIVALENTS FOR NON-PEPTIDES AND PROCEDURES FOR DEVELOPING THESE
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
AU656947B2 (en) * 1991-02-04 1995-02-23 Akzo N.V. Factor IIa inhibitors
CA2118806A1 (en) * 1991-09-18 1993-04-01 William J. Dower Method of synthesizing diverse collections of oligomers

Also Published As

Publication number Publication date
HUT75223A (en) 1997-04-28
AU1068295A (en) 1995-06-27
NO962186L (en) 1996-05-29
IL111906A0 (en) 1995-03-15
FI962371A (en) 1996-06-07
HU9601588D0 (en) 1996-08-28
JPH09508355A (en) 1997-08-26
CA2175078A1 (en) 1995-06-15
FI962371A0 (en) 1996-06-07
WO1995016209A1 (en) 1995-06-15
EP0733213A1 (en) 1996-09-25

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