UY29736A1 - Peptidos y compuestos que se fijan a un receptor - Google Patents

Peptidos y compuestos que se fijan a un receptor

Info

Publication number
UY29736A1
UY29736A1 UY29736A UY29736A UY29736A1 UY 29736 A1 UY29736 A1 UY 29736A1 UY 29736 A UY29736 A UY 29736A UY 29736 A UY29736 A UY 29736A UY 29736 A1 UY29736 A1 UY 29736A1
Authority
UY
Uruguay
Prior art keywords
peptides
receiver
compounds fixed
compounds
fixed
Prior art date
Application number
UY29736A
Other languages
English (en)
Inventor
Brian R Macdonald
Jeffery Kenneth Weis
Edward John Yurkow
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37734435&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY29736(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of UY29736A1 publication Critical patent/UY29736A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describen compuestos peptídicos que se unen y activan el receptor de trombopoyetina (c-mpl o TPO-R) o de otro modo actúan como agonistas de TPO.
UY29736A 2005-08-09 2006-08-09 Peptidos y compuestos que se fijan a un receptor UY29736A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/200,416 US7723295B2 (en) 2003-08-28 2005-08-09 Peptides and compounds that bind to a receptor

Publications (1)

Publication Number Publication Date
UY29736A1 true UY29736A1 (es) 2006-12-29

Family

ID=37734435

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29736A UY29736A1 (es) 2005-08-09 2006-08-09 Peptidos y compuestos que se fijan a un receptor

Country Status (35)

Country Link
US (1) US7723295B2 (es)
EP (1) EP1957517B1 (es)
JP (1) JP2009504650A (es)
KR (1) KR20080048026A (es)
CN (1) CN101287749A (es)
AR (1) AR055114A1 (es)
AU (1) AU2006280230B2 (es)
BR (1) BRPI0614647A2 (es)
CA (1) CA2618958A1 (es)
CR (1) CR9798A (es)
CY (1) CY1114032T1 (es)
DK (1) DK1957517T3 (es)
EA (1) EA200800535A1 (es)
EC (1) ECSP088169A (es)
ES (1) ES2419005T3 (es)
GT (1) GT200600361A (es)
HK (1) HK1123811A1 (es)
HR (1) HRP20130518T1 (es)
IL (1) IL189361A (es)
JO (1) JO2859B1 (es)
MY (1) MY152177A (es)
NI (1) NI200800040A (es)
NO (1) NO344405B1 (es)
NZ (1) NZ565497A (es)
PE (1) PE20070416A1 (es)
PL (1) PL1957517T3 (es)
PT (1) PT1957517E (es)
RS (1) RS52802B (es)
SI (1) SI1957517T1 (es)
SV (1) SV2008002648A (es)
TW (1) TWI400081B (es)
UA (1) UA96418C2 (es)
UY (1) UY29736A1 (es)
WO (1) WO2007021572A2 (es)
ZA (1) ZA200802184B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
EP2319528B8 (en) 2002-09-18 2020-03-04 Janssen Pharmaceuticals, Inc. Methods of increasing platelet and hematopoietic stem cell production
US20040149235A1 (en) * 2002-10-04 2004-08-05 Pogue Albert S. Apparatus and method for removal of waste from animal production facilities
US7615533B2 (en) * 2004-08-16 2009-11-10 Janssen Pharmaceutica N.V. TPO peptide compounds for treatment of anemia
WO2007087428A2 (en) * 2006-01-25 2007-08-02 Amgen Inc. Thrombopoietic compounds
KR20110015448A (ko) * 2008-06-03 2011-02-15 얀센 파마슈티카 엔.브이. 암 치료와 관련된 혈액 질환을 예방하기 위한 ｔｐｏ 모방 펩티드
CN103635514B (zh) 2011-06-23 2016-01-20 株式会社岛津制作所 支链型两亲性嵌段聚合物、使用其的分子聚集体及药物输送系统
BR112020001367A2 (pt) 2017-07-26 2020-08-11 Janssen Pharmaceutica N.V. métodos de proteção da integridade vascular induzida por terapia de radiação direcionada
KR20210141460A (ko) 2019-01-25 2021-11-23 잔센파마슈티카엔.브이. 방사선 및/또는 방사선 모방체 치료와 함께 간 손상을 완화하고 간 비대, 재생 및 세포 생착을 촉진하는 방법
JP2022523295A (ja) 2019-01-25 2022-04-22 ヤンセン ファーマシューティカ エヌ．ベー． 発疱剤および苛性ガスの毒性作用を緩和する方法
US20200237872A1 (en) 2019-01-25 2020-07-30 Janssen Pharmaceutica Nv Methods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure
CA3234340A1 (en) 2021-10-01 2023-04-06 Janssen Pharmaceutica N.V. Methods of increasing progenitor cell production
WO2024095178A1 (en) 2022-11-01 2024-05-10 Janssen Pharmaceutica Nv Thrombopoietin mimetic for use in the treatment of acute liver failure

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5326558A (en) * 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
IL96477A0 (en) 1989-12-01 1991-08-16 Amgen Inc Megakaryocyte production
DK167813B1 (da) * 1989-12-07 1993-12-20 Carlbiotech Ltd As Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
US5571508A (en) 1989-12-18 1996-11-05 Amrad Corporation Limited Method for the treatment of thrombocytopenia and pharmaceutical compositions useful therefor
IT1241395B (it) 1990-04-02 1994-01-10 Eniricerche Spa Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria
US5141851A (en) * 1990-04-18 1992-08-25 Board Of Regents, The University Of Texas System Isolated farnesyl protein transferase enzyme
US5250732A (en) * 1991-07-18 1993-10-05 Genentech, Inc. Ketamine analogues for treatment of thrombocytopenia
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
DE69332222T3 (de) 1992-06-11 2007-05-10 Alkermes Controlled Therapeutics, Inc., Cambridge Enythropoietin enthaltendes arzneimittelabgabesystem
EP0673387B1 (en) * 1992-12-11 1999-09-22 University Of Florida Materials and methods for control of pests
WO1995011922A1 (en) 1993-10-29 1995-05-04 Affymax Technologies N.V. In vitro peptide and antibody display libraries
GB2285446B (en) 1994-01-03 1999-07-28 Genentech Inc Thrombopoietin
EP0668352A1 (en) 1994-02-14 1995-08-23 Kirin Brewery Company, Ltd. Protein having TPO activity
PL178384B1 (pl) 1994-02-14 2000-04-28 Univ Washington Wydzielone białko, wydzielone cząsteczki polinukleotydowe, wektor ekspresji, hodowana komórka, kompozycja farmaceutyczna do stymulacji wytwarzania płytek krwi u ssaka, sposób wytwarzania białka homeopoezyjnego, sposób otrzymywania przeciwciał, sposób stymulacji i namnażania komórek
WO1995021626A1 (en) 1994-02-14 1995-08-17 University Of Washington Methods for stimulating erythropoiesis using thrombopoietin
WO1995021919A2 (en) 1994-02-14 1995-08-17 Kirin Brewery Company, Limited Protein having tpo activity
KR100303810B1 (ko) 1994-03-31 2001-12-01 스티븐 엠. 오드리 거핵구성장및분화를자극하기위한조성물및방법
US5571686A (en) 1994-04-14 1996-11-05 Massachusetts Institute Of Technology Method of using megapoietin for prolonging the survival & viability of platlets
WO1996017062A1 (en) 1994-11-30 1996-06-06 Zymogenetics, Inc. Low molecular weight thrombopoietin
DE69636714T2 (de) 1995-04-26 2007-10-18 Kyowa Hakko Kogyo Co., Ltd. G-CSF TPO Fusionsproteine
US6251864B1 (en) * 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
PE7898A1 (es) 1995-06-07 1998-03-05 Glaxo Group Ltd Peptidos compuestos que se ligan al receptor de trombopoietina
US5869451A (en) * 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6060052A (en) * 1995-10-30 2000-05-09 Systemix, Inc. Methods for use of Mpl ligands with primitive human hematopoietic stem cells
US5932546A (en) * 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
US6552008B1 (en) 1999-09-24 2003-04-22 Smithkline Beecham Corporation Thrombopoietin mimetics
WO2002078612A2 (en) 2001-04-02 2002-10-10 Euro-Celtique S.A. Thrombopoietin (tpo) synthebody for stimulation of platelet production
EP2319528B8 (en) 2002-09-18 2020-03-04 Janssen Pharmaceuticals, Inc. Methods of increasing platelet and hematopoietic stem cell production
NZ545455A (en) 2003-08-28 2009-02-28 Ortho Mcneil Pharm Inc Peptides and compounds that bind to thrombopoietin receptors

Also Published As

Publication number Publication date
ES2419005T3 (es) 2013-08-19
TW200744626A (en) 2007-12-16
AU2006280230A1 (en) 2007-02-22
CY1114032T1 (el) 2016-07-27
SV2008002648A (es) 2008-11-28
NO20081298L (no) 2008-04-23
NO344405B1 (no) 2019-12-02
AU2006280230B2 (en) 2012-11-08
DK1957517T3 (da) 2013-04-08
JO2859B1 (en) 2015-03-15
MY152177A (en) 2014-08-15
EP1957517B1 (en) 2013-03-20
KR20080048026A (ko) 2008-05-30
RS52802B (en) 2013-10-31
WO2007021572A3 (en) 2007-06-07
ECSP088169A (es) 2008-03-26
WO2007021572A2 (en) 2007-02-22
US20060040866A1 (en) 2006-02-23
BRPI0614647A2 (pt) 2011-04-12
ZA200802184B (en) 2009-08-26
IL189361A (en) 2015-11-30
CA2618958A1 (en) 2007-02-22
SI1957517T1 (sl) 2013-07-31
NI200800040A (es) 2010-11-25
PT1957517E (pt) 2013-05-28
CR9798A (es) 2008-09-09
TWI400081B (zh) 2013-07-01
CN101287749A (zh) 2008-10-15
HRP20130518T1 (hr) 2013-07-31
EA200800535A1 (ru) 2008-08-29
NZ565497A (en) 2011-10-28
PE20070416A1 (es) 2007-06-13
JP2009504650A (ja) 2009-02-05
UA96418C2 (ru) 2011-11-10
AR055114A1 (es) 2007-08-08
IL189361A0 (en) 2008-06-05
HK1123811A1 (en) 2009-06-26
US7723295B2 (en) 2010-05-25
PL1957517T3 (pl) 2013-08-30
EP1957517A2 (en) 2008-08-20
GT200600361A (es) 2007-03-14

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Legal Events

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Effective date: 20170424