KEGG   ENZYME: 1.1.1.425
Entry
EC 1.1.1.425                Enzyme                                 
Name
levoglucosan dehydrogenase;
1,6-anhydro-beta-D-glucose dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
1,6-anhydro-beta-D-glucopyranose:NAD+ 3-oxidoreductase
Reaction(IUBMB)
levoglucosan + NAD+ = 3-dehydrolevoglucosan + NADH + H+ [RN:R12713]
Reaction(KEGG)
R12713
Substrate
levoglucosan [CPD:C22350];
NAD+ [CPD:C00003]
Product
3-dehydrolevoglucosan [CPD:C22351];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Levoglucosan is formed from the pyrolysis of carbohydrates such as starch and cellulose and is an important molecular marker for pollution from biomass burning. This enzyme is present only in bacteria, and has been characterized from Arthrobacter sp. I-552 and Pseudarthrobacter phenanthrenivorans. cf. EC 2.7.1.232, levoglucosan kinase.
History
EC 1.1.1.425 created 2021
Orthology
K24995  levoglucosan dehydrogenase
Genes
PEZ: HWQ56_09195
PALV: KSS97_18160
RFO: REIFOR_02758(iolG)
BURM: GJG85_29655
MESJ: MJ8_10540
SMI: BN406_06768
RHI: NGR_b19940
SFD: USDA257_c18000 USDA257_c18100
SAME: SAMCFNEI73_pC1598
AGRC: GSF67_26040 GSF67_26100
REL: REMIM1_PF00849 REMIM1_PF00875
REP: IE4803_CH03661 IE4803_CH03684
RLT: Rleg2_4779
RGR: FZ934_12315
PHL: KKY_2595 KKY_3864
PEM: OF122_01755
DEI: C4375_04075
DSAL: K1X15_12760
FYT: QF092_17510
PZH: CX676_22085
PTP: RCA23_c12140
LVS: LOKVESSMR4R_02604(iolX)
FAQ: G5B39_17710
BACQ: DOE78_19795
BCO: Bcell_0373 Bcell_0375
BMQ: BMQ_1775
BMD: BMD_3622
BMEG: BG04_545
BFX: BC359_10195
BKW: BkAM31D_16255(gfo_2)
FEC: QNH15_23435
ACOP: RI196_17985
SALE: EPH95_12700
NTM: BTDUT50_05740
MEKU: HUW50_14340
MDG: UNJ81145.1
MLIT: KDJ21_026285
MEBZ: LPC09_05220
MRL: WCV66_25175
DOM: RRU94_18690 RRU94_18985
SHV: AAT16_11375 AAT16_11385
PPY: PPE_00856
POW: IJ21_32400 IJ21_33360
ANEU: PP175_11360 PP175_17505
COH: EAV92_02890
AFAS: NZD89_04425
FFE: LSG31_21240
JEO: JMA_08640 JMA_08660
EAV: EH197_20100
BCOC: BLCOC_12790(iolG_7) BLCOC_12850(iolG_8)
LUA: D4A81_10270
WHJ: H9Q79_00380 H9Q79_00410
CMIU: B1H56_01165
TEX: Teth514_0988
THX: Thet_1927
GTA: BCM27_04660
AREV: RVR_8031
MLV: CVS47_02172(afr_3)
MSF: IT882_02490
MLIY: RYJ27_11955
RLA: Rhola_00001010
ART: Arth_1911
ARTH: C3B78_05130
ARTY: AHiyo4_11790
PUE: FV140_21400
PNV: JMY29_03820
PAYJ: HMI59_19505
PAGO: IRJ34_10040
PAYN: HMI60_08035
PHRZ: QN084_10270
APN: Asphe3_10730
PDEL: JCQ34_05035
POK: SMD14_05310 SMD14_05515
PSLS: KTR40_05045
PSFE: NG819_19630
PQA: WHH00_13615
GLM: N6V40_05425
KFV: AS188_10240
MLY: CJ228_009200
SATK: SA2016_1510
TEZ: BKM78_07725
TLA: TLA_TLA_01561(iolX_2)
NHY: JQS43_03090
DGO: DGo_PB0088
DAH: DAETH_26080
 » show all
Reference
1  [PMID:7765713]
  Authors
Nakahara K, Kitamura Y, Yamagishi Y, Shoun H, Yasui T.
  Title
Levoglucosan dehydrogenase involved in the assimilation of levoglucosan in Arthrobacter sp. I-552.
  Journal
Biosci Biotechnol Biochem 58:2193-6 (1994)
DOI:10.1271/bbb.58.2193
Reference
2  [PMID:30224354]
  Authors
Sugiura M, Nakahara M, Yamada C, Arakawa T, Kitaoka M, Fushinobu S.
  Title
Identification, functional characterization, and crystal structure determination of bacterial levoglucosan dehydrogenase.
  Journal
J Biol Chem 293:17375-17386 (2018)
DOI:10.1074/jbc.RA118.004963
  Sequence
[apn:Asphe3_10730]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.425
IUBMB Enzyme Nomenclature: 1.1.1.425
ExPASy - ENZYME nomenclature database: 1.1.1.425
BRENDA, the Enzyme Database: 1.1.1.425
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