KEGG ENZYME: 1.1.99.39

ENZYME: 1.1.99.39

Entry

EC 1.1.99.39                Enzyme

Name

D-2-hydroxyglutarate dehydrogenase;
D2HGDH (gene name)

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With unknown physiological acceptors

Sysname

(R)-2-hydroxyglutarate:acceptor 2-oxidoreductase

Reaction(IUBMB)

(R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor [RN:R10575]

Reaction(KEGG)

R10575

Substrate

(R)-2-hydroxyglutarate [CPD:C01087];
acceptor [CPD:C00028]

Product

2-oxoglutarate [CPD:C00026];
reduced acceptor [CPD:C00030]

Comment

Contains FAD. The enzyme has no activity with NAD+ or NADP+, and was assayed in vitro using artificial electron acceptors. It has lower activity with (R)-lactate, (R)-2-hydroxybutyrate and meso-tartrate, and no activity with the (S) isomers. The mammalian enzyme is stimulated by Zn2+, Co2+ and Mn2+.

History

EC 1.1.99.39 created 2013

Orthology

K18204

D-2-hydroxyglutarate dehydrogenase

Genes

HSA:	728294(D2HGDH)

PTR:	748707(D2HGDH)

PPS:	100983509(D2HGDH)

GGO:	101133731(D2HGDH)

PON:	100441178(D2HGDH)

PPYG:

129031669(D2HGDH)

NLE:	100598101 115832318

HMH:	116814100(D2HGDH)

SSYN:

129488689(D2HGDH)

MCC:	702028(D2HGDH)

MCF:	102118732(D2HGDH)

MTHB:

126932787

MNI:	105473753(D2HGDH)

CSAB:

103218250(D2HGDH)

CATY:

105577220(D2HGDH)

PANU:

101024261(D2HGDH)

TGE:	112616999 112617011

MLEU:

105551231(D2HGDH)

RRO:	104673075(D2HGDH)

RBB:	108528714(D2HGDH)

TFN:	117094260(D2HGDH)

PTEH:

111528407(D2HGDH)

CANG:

105502869(D2HGDH)

CJC:	100398724(D2HGDH)

SBQ:	101043256(D2HGDH)

CIMI:

108290771(D2HGDH)

ANAN:

105705512(D2HGDH)

CSYR:

103251251(D2HGDH)

MMUR:

105866389(D2HGDH)

LCAT:

123643304(D2HGDH)

PCOQ:

105824496(D2HGDH)

OGA:	100942059(D2HGDH)

MMU:	98314(D2hgdh)

MCAL:

110299299(D2hgdh)

MPAH:

110322207(D2hgdh)

RNO:	301624(D2hgdh)

MCOC:

116088812(D2hgdh)

ANU:	117722252(D2hgdh)

ASYL:

127692457(D2hgdh)

MUN:	110545727(D2hgdh)

CGE:	100773592(D2hgdh)

MAUA:

101843502(D2hgdh)

PROB:

127226737(D2hgdh)

PLEU:

114707803(D2hgdh)

MORG:

121433542 121446704

MFOT:

126490776

AAMP:

119820883(D2hgdh)

NGI:	103730854(D2hgdh)

HGL:	101721825(D2hgdh)

CPOC:

100730010(D2hgdh)

CCAN:

109682469(D2hgdh)

DORD:

105998845(D2hgdh)

DSP:	122125111(D2hgdh)

PLOP:

125350108(D2hgdh)

NCAR:

124979565

MMMA:

107138879(D2hgdh)

ITI:	101973691(D2hgdh)

OCU:

100343021

OPI:	101521351(D2HGDH)

TUP:	102498469(D2HGDH)

GVR:	103595368(D2HGDH)

CFA:	609641(D2HGDH)

CLUD:

112670046(D2HGDH)

VVP:	112911244(D2HGDH)

VLG:	121497325(D2HGDH)

NPO:	129493753(D2HGDH)

AML:	100479601(D2HGDH)

UMR:	103662596(D2HGDH)

UAH:	113249272(D2HGDH)

UAR:	123791221(D2HGDH)

ELK:

111142961

LLV:

125095348

MPUF:

101685457(D2HGDH)

MNP:	132013734(D2HGDH)

MLK:	131827235(D2HGDH)

NVS:	122902488(D2HGDH)

ORO:	101366055(D2HGDH)

EJU:	114210736(D2HGDH)

ZCA:	113920191(D2HGDH)

MLX:	118011858(D2HGDH)

NSU:	110570956(D2HGDH)

FCA:	101098076(D2HGDH)

PYU:	121014306(D2HGDH)

PCOO:

112867777(D2HGDH)

PBG:	122482020(D2HGDH)

PVIV:

125158883(D2HGDH)

LRUF:

124516057

LGF:	123599745(D2HGDH)

AJU:

106984596

PTG:	102957898(D2HGDH)

PPAD:

109264778(D2HGDH)

PUC:

125910972

PLEZ:

122226909(D2HGDH)

HHV:	120229545(D2HGDH)

BTA:	533003(D2HGDH)

BOM:	102270610(D2HGDH)

BIU:	109556611(D2HGDH)

BBUB:

102398678(D2HGDH)

BBIS:

104983453(D2HGDH)

CHX:	102191395 108633807

OAS:	101121480(D2HGDH)

BTAX:

128044747(D2HGDH)

CSUM:

138072998(D2HGDH)

ODA:	120856634(D2HGDH)

CCAD:

122437346(D2HGDH)

MREE:

136155478(D2HGDH)

OVR:	110150293(D2HGDH)

MBEZ:

129541106(D2HGDH)

SSC:	106508365(D2HGDH)

CFR:	102518026(D2HGDH)

CBAI:

105063522(D2HGDH)

CDK:	105096195(D2HGDH)

VPC:	102543891(D2HGDH)

BACU:

103015223(D2HGDH)

BMUS:

118898349(D2HGDH)

LVE:	103086049(D2HGDH)

OOR:	101284861(D2HGDH)

LALB:

132521942(D2HGDH)

DLE:	111172020(D2HGDH)

PCAD:

102985238(D2HGDH)

PSIU:

116756591(D2HGDH)

NASI:

112407896(D2HGDH)

ECB:	100067872(D2HGDH)

EPZ:	103560352(D2HGDH)

EAI:	106844914(D2HGDH)

MYB:	102261514(D2HGDH)

MYD:	102768727(D2HGDH)

MMYO:

118661619(D2HGDH)

MLF:	102422829(D2HGDH)

MDT:	132238448(D2HGDH)

MYUM:

139015176(D2HGDH)

PKL:	118709087(D2HGDH)

EFUS:

103283464(D2HGDH)

MNA:	107530053(D2HGDH)

DRO:	112307965(D2HGDH)

SHON:

119003065(D2HGDH)

AJM:	119061027(D2HGDH)

PDIC:

114494433(D2HGDH)

PHAS:

123823235(D2HGDH)

MMF:	118625826(D2HGDH)

PPAM:

129068248(D2HGDH)

HAI:	109374862(D2HGDH)

RFQ:	117025882(D2HGDH)

PALE:

102878813(D2HGDH)

PGIG:

120601634(D2HGDH)

PVP:	105302985(D2HGDH)

RAY:	107505225(D2HGDH)

MJV:	108388599(D2HGDH)

TOD:	119256363(D2HGDH)

SARA:

101541569(D2HGDH)

SFUM:

130017670(D2HGDH)

SETR:

126009072(D2HGDH)

LAV:	100665076(D2HGDH)

TMU:

101351799

DNM:	101435515(D2HGDH)

MDO:	100012430(D2HGDH)

GAS:	123242019(D2HGDH)

SHR:	100930000(D2HGDH)

AFZ:

127558340

PCW:	110210175(D2HGDH)

TVP:	118847475(D2HGDH)

PBRV:

138157667(D2HGDH)

OAA:	100082378(D2HGDH)

TACU:

119930595(D2HGDH)

GGA:	424853(D2HGDH)

PCOC:

116230994(D2HGDH)

MGP:	100542797(D2HGDH)

CJO:	107317964(D2HGDH)

TPAI:

128082240(D2HGDH)

LMUT:

125697681(D2HGDH)

NMEL:

110398201(D2HGDH)

APLA:

101797675(D2HGDH)

ACYG:

106039274(D2HGDH)

CATA:

118247223(D2HGDH)

AFUL:

116492737(D2HGDH)

TGU:	100218606(D2HGDH)

LSR:	110478632(D2HGDH)

SCAN:

103815517(D2HGDH)

PMOA:

120511246(D2HGDH)

OTC:	121342171(D2HGDH)

PRUF:

121364097(D2HGDH)

ATRC:

139594811(D2HGDH)

GFR:	102043646(D2HGDH)

FAB:	101812765(D2HGDH)

OMA:	130256585(D2HGDH)

PHI:	102103390(D2HGDH)

PMAJ:

107208912(D2HGDH)

CCAE:

111933731(D2HGDH)

CCW:	104696747(D2HGDH)

CBRC:

103612003(D2HGDH)

ACOE:

138114814(D2HGDH)

ETL:	114069386(D2HGDH)

ZAB:	102071126(D2HGDH)

ZLE:	135451638(D2HGDH)

ACHL:

103800350(D2HGDH)

SVG:	106849654(D2HGDH)

MMEA:

130582333(D2HGDH)

HRT:	120757437(D2HGDH)

SATI:

136365558(D2HGDH)

CCIC:

134047796(D2HGDH)

FCH:	102048188(D2HGDH)

CCRI:

104159137(D2HGDH)

NNT:	104406132(D2HGDH)

SHAB:

115612161(D2HGDH)

ACUN:

113483721(D2HGDH)

TALA:

104363551

ACHC:

115347017(D2HGDH)

HALD:

104316905

HLE:	104827892(D2HGDH)

AGEN:

126039978

HHAR:

128149403(D2HGDH)

GCL:

127020296

LDI:	104347757(D2HGDH)

MNB:	103768257(D2HGDH)

DPUB:

104299314(D2HGDH)

PPUS:

135186821(D2HGDH)

AVIT:

104281266(D2HGDH)

BRHI:

104490931(D2HGDH)

EGZ:	104131328(D2HGDH)

NNI:	104010684(D2HGDH)

PCRI:

104037916(D2HGDH)

PCAO:

104050644(LDHD)

PADL:

103915931(D2HGDH)

AFOR:

103903726(D2HGDH)

FGA:

104074593

GSTE:

104252061(D2HGDH)

CLV:	102096725(D2HGDH)

MUI:	104544172(D2HGDH)

PGUU:

104459144

PLET:

104614705

EHS:	104513482(D2HGDH)

CMAC:

104484278(D2HGDH)

TEO:	104379540(D2HGDH)

BREG:

104636799(D2HGDH)

OHA:	104335091(D2HGDH)

CPEA:

104387948(D2HGDH)

CVF:	104286754(D2HGDH)

RTD:	128911436(D2HGDH)

AAM:	106492631(D2HGDH)

AROW:

112972246(ING5)

NPD:	112944860(D2HGDH)

TGT:	104577286(D2HGDH)

DNE:	112989480(D2HGDH)

SCAM:

104138935(D2HGDH)

ASN:	102385710(ING5)

AMJ:	102572947(D2HGDH)

CPOO:

109315345(ING5)

GGN:

109294754

PSS:	102462295(D2HGDH)

CMY:	102934724(D2HGDH)

CCAY:

125642353(D2HGDH)

DCC:	119861723(D2HGDH)

CPIC:

101949760(D2HGDH)

TST:	117882836(D2HGDH)

CABI:

116834027(D2HGDH)

MRV:	120371635(D2HGDH)

ACS:	100553833(d2hgdh)

ASAO:

132770727(D2HGDH)

PVT:	110075295(D2HGDH)

SUND:

121926033(D2HGDH)

PBI:	103060731(D2HGDH)

PMUR:

107294960(D2HGDH)

CTIG:

120297675(D2HGDH) 120319511

TSR:	106555203(D2HGDH)

PGUT:

117678447(D2HGDH)

APRI:

131200924(D2HGDH)

PTEX:

113436807(D2HGDH)

NSS:	113431415(D2HGDH)

VKO:	123024717(D2HGDH)

PMUA:

114597736(D2HGDH)

PRAF:

128414509(D2HGDH)

ZVI:	118093886(D2HGDH)

HCG:	128352263(D2HGDH)

GJA:	107114547(D2HGDH)

STOW:

125437438(D2HGDH)

EMC:	129332230(D2HGDH)

XLA:	108718159(d2hgdh.S)

XTR:	100379761(d2hgdh)

NPR:	108793034(D2HGDH)

RTEM:

120936500(D2HGDH)

BBUF:

120997709(D2HGDH)

BGAR:

122935895(D2HGDH)

PWL:	138265688(D2HGDH)

MUO:	115466100(D2HGDH)

GSH:	117354397(D2HGDH)

DRE:	565889(d2hgdh)

SRX:

107749221

SANH:

107678686

SGH:

107602612

CCAR:

109054201(d2hgdh)

CAUA:

113045132(d2hgdh)

CGIB:

127950725

PTET:

122328208(d2hgdh)

LROH:

127177949(d2hgdh)

OMC:	131522319(d2hgdh)

PPRM:

120465092(d2hgdh)

MAMB:

125250768(d2hgdh)

CIDE:

127494575 127524593

CERY:

137002606(d2hgdh)

MASI:

127441919

TROS:

130553917(d2hgdh)

TDW:	130417347(d2hgdh)

MANU:

129442888 129442889

PDAB:

135748710(d2hgdh)

IPU:

108267866

IFU:	128609668(d2hgdh)

PHYP:

113540099(d2hgdh)

SMEO:

124387122(d2hgdh)

TFD:	113644078(d2hgdh)

TVC:	132848295(d2hgdh)

CGAR:

128519411(d2hgdh)

NGRA:

132891691(d2hgdh)

TRN:	134312118(d2hgdh)

AMEX:

103041769(d2hgdh)

CMAO:

118825506(d2hgdh)

EEE:	113584248(d2hgdh)

CHAR:

105907203(d2hgdh)

SPIL:

134061482(d2hgdh)

TRU:	101062526(d2hgdh)

TFS:	130540405(d2hgdh)

TNG:	GSTEN00031943G001

LCO:	104926586(d2hgdh)

NCC:	104965960(d2hgdh)

TBEN:

117493020(d2hgdh)

CGOB:

115027093(d2hgdh)

PGEO:

117468164(d2hgdh)

GACU:

117540595(d2hgdh)

EMAC:

134881623(d2hgdh)

ELY:	117266998(d2hgdh)

EFO:	125900505(d2hgdh)

PLEP:

121953271(d2hgdh)

SLUC:

116057625(d2hgdh)

ECRA:

117935853(d2hgdh)

ESP:	116669946(d2hgdh)

PFLV:

114546859(d2hgdh)

GAT:	120832436(d2hgdh)

PPUG:

119227371(d2hgdh)

AFB:	129103492(d2hgdh)

CLUM:

117751307(d2hgdh)

PSWI:

130190004(d2hgdh)

CANA:

137787704(d2hgdh)

MSAM:

119910626(d2hgdh)

SCHU:

122862074(d2hgdh)

CUD:	121525871(d2hgdh)

SPUL:

138590814(d2hgdh)

LMIX:

132993524(d2hgdh)

ALAT:

119004538(d2hgdh)

ASTR:

137610982(d2hgdh)

MZE:	101466758(d2hgdh)

ONL:	100706461(d2hgdh)

OAU:	116326086(d2hgdh)

OLA:	101158736(d2hgdh)

OML:	112143128(d2hgdh)

CSAI:

133462942(d2hgdh)

XMA:	102225785(d2hgdh)

XCO:	114134097(d2hgdh)

XHE:	116708868(d2hgdh)

PRET:

103458471(d2hgdh)

PFOR:

103155255(d2hgdh)

PLAI:

106953019(d2hgdh)

PMEI:

106906215(d2hgdh)

GAF:	122845576(d2hgdh)

PPRL:

129365221(d2hgdh)

CVG:	107093032(d2hgdh)

CTUL:

119775509(d2hgdh)

GMU:	124884850(d2hgdh)

NFU:	107392116(d2hgdh)

KMR:	108235694(d2hgdh)

ALIM:

106518470(d2hgdh)

NWH:	119427412(d2hgdh)

AOCE:

111580334(d2hgdh)

EJA:	138200114(d2hgdh)

BFRE:

138627968(d2hgdh)

MCEP:

125023610(d2hgdh)

CSEM:

103380089(d2hgdh)

POV:	109636414(d2hgdh)

SSEN:

122782532(d2hgdh)

SSOE:

131444464(d2hgdh)

HHIP:

117756781(d2hgdh)

HSP:	118116362(d2hgdh)

PPLT:

128450834(d2hgdh)

SMAU:

118286162(d2hgdh)

LCF:

108874997

SDU:	111225383(d2hgdh)

SLAL:

111670157(d2hgdh)

XGL:	120795754(d2hgdh)

HCQ:	109517366(d2hgdh)

SSCV:

125981016(d2hgdh)

SBIA:

133513834(d2hgdh)

PEE:	133412365(d2hgdh)

PTAO:

133488089(d2hgdh)

BPEC:

110155086(d2hgdh)

MALB:

109968014(d2hgdh)

BSPL:

114848127(d2hgdh)

SJO:	128375118(d2hgdh)

SSCO:

134000515(d2hgdh)

GMH:	115544126(d2hgdh)

SASA:

106574512 106575380

STRU:

115179415

OTW:	112239061(d2hgdh)

OMY:	110528875(d2hgdh)

OGO:	124007774(d2hgdh)

ONE:

115120789

OKI:	109890559(d2hgdh)

OKE:

118376913

OMM:	135542654(d2hgdh)

OCLA:

139412953

SALP:

112076963(d2hgdh)

SNH:	120033538(d2hgdh)

CCLU:

121560557(d2hgdh)

ELS:	105019987(d2hgdh)

SFM:	108936634(d2hgdh)

PKI:	111847356(d2hgdh)

AANG:

118228997(d2hgdh)

AROT:

135256756(d2hgdh)

CCOG:

133128095(d2hgdh)

LOC:	102690226(d2hgdh)

PSPA:

121323084

ARUT:

117422959(d2hgdh)

PSEX:

120534571(d2hgdh)

LCM:	102352928(D2HGDH)

CMK:	103174498(d2hgdh)

RTP:	109922111(d2hgdh)

CPLA:

122555692(d2hgdh)

HOC:	132821634(d2hgdh)

LERI:

129703456(d2hgdh)

PMRN:

116939836(D2HGDH)

LRJ:

133350377

BFO:	118423164 118430432

BBEL:

109465653 109479756

CIN:

100177536

SCLV:

120342252

SPU:

578006

LPIC:

129276480 129276490

AJJ:	139975513 139975633

APLC:

110978983

ARUN:

117302775

AAMU:

139950617

AFIL:

140156841

SKO:

100367659

PFLL:

139137280

DME:	Dmel_CG3835(D2hgdh)

DER:

6555624

DSE:

6616092

DSI:	Dsimw501_GD16587(Dsim_GD16587)

DYA:	Dyak_GE16237

DAN:

6504144

DSR:

110180129

DPO:

4814294

DPE:

6596890

DMN:

108151702

DWI:

6648673

DGR:

6566361

DMO:	Dmoj_GI11068

DAZ:

108618702

DNV:

108657278

DHE:

111593424

DVI:	6633265(D2hgdh)

CCAT:

101452249 101452433

BOD:	106625574 106625737

BDR:	105224336 105224337

RZE:	108365522 108380307

AOQ:	129239351 129239352

TDA:

119668554

MDE:	101898784 131801867

SCAC:

106093131 106093133

LCQ:	111675138 111675149

LSQ:	119599689 119599706 119599803 119599816

CVJ:	135957867(D2hgdh) 135958835

GFS:

119642858

ECOE:

129948281

CLON:

129605265

HIS:

119646869

AGA:

1274029

ACOZ:

120953295

AARA:

120898518

AMER:

121590864

ASTE:

118503011

AMAP:

126557761

AFUN:

125761278

AMOU:

128309773

AALI:

118460649

AAG:

5567262

AALB:

109416301

ASUA:

134224224

CQU:	CpipJ_CPIJ001318

CPII:

120413979

CNS:	116339911 116339912

BCOO:

119078072

LLL:

129793195

PPAP:

129803416

AME:

726115

ACER:

108003615

ALAB:

122720719

ADR:

102671367

AFLR:

100866054

BIM:

100746986

BBIF:

117211609

BVK:

117241384

BVAN:

117157928

BHUN:

126869301

BTER:

100651710

BAFF:

126919236

BPYO:

122566791

BPAS:

132910919

FVI:

122538782

CCAL:

108629843

OBB:

114873620

OLG:

117601107

MGEN:

117229274

NMEA:

116429971

CGIG:

122399993

SOC:

105199825

MPHA:

105837297

AEC:

105147989

ACEP:

105623515

PBAR:

105431248

VEM:

105560573

COBS:

139110803(D2hgdh)

TLN:	139809225(D2hgdh)

HST:

105190242

DQU:

106747688

CFO:

105250685

FEX:

115238085

PMEC:

138939941(D2hgdh)

LHU:	105679351(D2hgdh)

PGC:

109859645

OBO:

105283001

PCF:

106788573

PFUC:

122522662

VPS:

122627263

VCRB:

124429816

VVE:

124957788

NVI:

100115941

CSOL:

105363575

TPRE:

106655364

LHT:

122499508

MDL:

103575679

CGLO:

123267754

FAS:

105273300

DAM:

107040112

AGIF:

122856800

CINS:

118072191

VCAN:

122416989

CCIN:

107271561

DSM:

124409879

NPT:	124215803(D2hgdh)

NFB:

124181175

NLO:

107219585

NVG:

124304090

AROA:

105691387

TCA:	655110 655187

TMOL:

138131838 138131839(D2hgdh)

DPA:	109537527 109546749

ESIM:

136415957 136419310(D2hgdh)

EFOR:

136339099 136344071(D2hgdh)

SOY:	115876281 115879531

AGRG:

126743880 126745773

ATD:	109594272 109594299

CSET:

123311542 123313207

HAXR:

123672682 123677365

AGB:	108909935 108909939 108909941 111692762

LDC:	111508459 111514468 111514684

DVV:	114329021 114342188

NVL:	108561070 108561076

APLN:

108736897 108736919

PPYR:

116170989 116170991

OTU:

111427942

BMOR:

101739171

BMAN:

114253523

MSEX:

115453349

DPL:	KGM_202444

BANY:

112055179

MJU:

123867132

NIQ:

126768500

VCD:

124530741

MCIX:

123654362

PMAC:

106714808

PPOT:

106105481

PXU:

106125414

BPHI:

137930842(D2hgdh)

PRAP:

111002266

PBX:

123707363

PNAP:

125055974

ZCE:

119831014

CCRC:

123692219

LSIN:

126969454

AAGE:

121730897

HAW:

110384058

HZE:

124630313

TNL:

113495466

SLIU:

111349619 111349620

OFU:	114353898 114353906

ONU:	135071462 135088567

ATRA:

106133073 106133094

GMW:	113511759 113511824

PXY:

105388680

PGW:

126366857

LGLY:

125226218

CSTB:

134742880

CFEL:

113367308 113367311

CCRN:

123293843

API:	100158944 100160552

DNX:	107164554 107174155

AGS:	114121093 114127806

RMD:	113548437 113548618

ACOO:

126834727 126836239

DVT:	126905201 126910362

BTAB:

109031817

CLEC:

106663085

HHAL:

106677210 106677211(D2hgdh)

NLU:

111056232

HVI:	124360809 124360892

MQU:	128985791 128992366 128992688 128993510

PHU:	Phum_PHUM396380

FOC:	113212955 113217726

TPAL:

117641822 117642329 117645170

ZNE:

110838308

CSEC:

111867739

SGRE:

126343077

BROR:

134542027 134542437

IEL:

124164522

HAMR:

139696213(D2hgdh)

FCD:	110843169 110854101

DPX:	DAPPUDRAFT_307847

DMK:

116922722

DPZ:

124320336

AFRA:

136027331

PVM:

113824062

PJA:

122255493

PCHN:

125043795

PMOO:

119585762

HAME:

121873037

PCLA:

123770317(D2hgdh)

CQD:	128703434(D2hgdh)

PTRU:

123515392 123515397

ESN:	127001938 127002075

MNZ:

135211092

MRJ:	136828878(D2hgdh)

PORN:

139747420(D2hgdh)

HAZT:

108678492

EAF:

111697499

LSM:	121121028(D2hgdh)

TCF:

131877178

PPOI:

119089496 119089542 119089543 119098540 119106195

DSV:

119444259

RMP:

119159354

VDE:

111251369

VJA:

111272689

TUT:

107366252

DPTE:

113788864

DFR:

124498027

CSCU:

111623056

CVS:	136985227(D2hgdh)

PTEP:

107440644

ABRU:

129988122

SDM:

118189070

LPOL:

106470011 106471714

PMEO:

129583835 129583924 129583992

CEL:	CELE_F54D5.12(dhgd-1)

CBR:

CBG_02865

CRQ:	GCK72_005320

NAI:	NECAME_11738

HRO:	HELRODRAFT_64272

LGI:	LOTGIDRAFT_182587

PVUL:

126827404

PCAN:

112557152

LSAX:

138978650

BGT:

106057460

GAE:

121389931

HRF:

124124475

HRJ:

124285724

HASI:

137268131

HCRA:

139470681

CRG:

105345903

CANU:

128190677

CVN:

111133078

OED:

125678930

MYI:

110450560

PMAX:

117314730

AIRR:

138316421

MCAF:

127720150

MMER:

123526408 128551545

RPHI:

132737816

DPOL:

127842899

MAEA:

128245537

OBI:

106880187

OSN:

115217886

LJP:	135475929 135475930

LAK:

106163454

LLON:

135497288

NVE:

5510548

EPA:

110246175

ATEN:

116291277

ADF:

107357723

AMIL:

114966519

MCAZ:

138019591

MFOO:

137998761

PDAM:

113675750

SPIS:

111346062

DGT:

114538183

XEN:

124442709

HMG:

100197520

HSY:

130645517

RES:

135696048

TAD:	TRIADDRAFT_31230 TRIADDRAFT_60696

AQU:

100642132

ATH:	AT4G36400(D2HGDH)

ALY:

9305109

CRB:

17880136

CSAT:

104716494 104721134 104729545

EUS:	EUTSA_v10000690mg EUTSA_v10024815mg

BRP:

103862468

BNA:	106411402 106451960

BOE:

106301382

RSZ:	108848905 130503948

THJ:

104807474

CPAP:

110822331

CIT:

102622615

CIC:	CICLE_v10025317mg

PVY:

116118961

MINC:

123199670

TCC:

18610845

GRA:

105776901

GHI:	107897617 107914279

GAB:

108489317

HSYR:

120159588 120185549

DZI:

111300067

EGR:	104419693 120288224

RARG:

115736249

GMX:

100811898

GSJ:

114420153

PVU:

137835433

VRA:

106777951

VAR:

108334624

VUN:

114166299

VUM:

124834817

CCAJ:

109800121

APRC:

113868832

MTR:

11412170

TPRA:

123910394

CAM:

101489255

PSAT:

127095029 127120190

VVO:

131646766

LJA:

130740668

ADU:

107488017

AIP:

107642924

AHF:	112717690 112749493 112800773

LANG:

109331964

PCIN:

129322775

QSA:	O6P43_033651

FVE:

101309000

AANS:

126793271

RCN:

112186438

PPER:

18771746

PMUM:

103340152

PAVI:

110773625

PDUL:

117635000

MDM:

103401099

MSYL:

126604506

PCOX:

137730965

ZJU:

107424558

MNT:

21396423

CSAV:

115714984

CSV:

101216583

CMO:

103493219

BHJ:

120085139

MCHA:

111008299

CMAX:

111483383

CMOS:

111436053

CPEP:

111809927

RCU:

8279120

MEAN:

126678009

JCU:

105634606

HBR:

110639579

MESC:

110601604

POP:

7480149

PEU:

105126646

PALZ:

118063089

PNZ:

133672511

JRE:

108992030

CILL:

122316626

CAVE:

132168728

AGLU:

133852421

QSU:

112000877

QLO:	115963181 115994300

TWL:

120016795

VVI:

100253926

VRI:

117912768

SLY:

101247582

SPEN:

107008794

SOT:

102597625

SSTN:

125850767

SDUL:

129875123

CANN:

107858548

LBB:

132621298

NTA:	107819913 107820135

NSY:

104240537

NTO:

104084861

NAU:

109237171

INI:

109172711

ITR:

116018743

SIND:

105165749

OEU:

111401940

EGT:

105965267

SSPL:

121774821 121777170

SMIL:

130986716

SHIS:

125201162

APAN:

127266075

HAN:

110867933

ECAD:

122603267

LSV:

111913333

CCAV:

112509609

DCR:

108223736

CSIN:

114255971

RVL:	131301764 131314665

AEW:

130778077

DLT:

127804009

BVG:

104895090

SOE:

110798890

CQI:	110682554 110685858

ATRI:

130807843

MOF:

131147041

NNU:

104610558

MING:

122073985

TSS:

122661966

PSOM:

113355555

OSA:	4342598(D2HGDH)

OBR:

102708729

OGL:

127778694

BDI:

100825375

ATS:

109763602

TDC:	119356462 119365648

TAES:

123046715 123054564 123190424

TUA:

125539704

LPER:

127322056

LRD:	124674000 124678476

SBI:

110432907

ZMA:

100273608

MFLO:

136545351 136549482 136551036

SITA:

101752911

PVIR:

120659565 120664339

PHAI:

112883206

PAUA:

133890592

PDA:

103717795

EGU:

105053375

MUS:

103981967

ZOF:	121979315 122037896

DCT:

110103843

PEQ:

110029259

AOF:

109834074

MSIN:

131233918

ACAK:

137934507

NCOL:

116266371

ATR:

18429284

CJF:

131060922

SMO:	SELMODRAFT_76083 SELMODRAFT_83489

PPP:

112278127

CRE:	CHLRE_08g370550v5

VCN:	VOLCADRAFT_63840

MNG:

MNEG_7161

CSL:	COCSUDRAFT_46474

CVR:	CHLNCDRAFT_26350

APRO:

F751_2783

OLU:	OSTLU_39945

OTA:	OT_ostta01g00240

BPG:	Bathy01g00120

MIS:	MICPUN_58844

MPP:	MICPUCDRAFT_36867

CME:	CYME_CMR349C

GSL:	Gasu_04450

MBR:	MONBRDRAFT_25135

SRE:	PTSG_09651

DDI:	DDB_G0270500

DPP:	DICPUDRAFT_158305

DFA:

DFA_11683

ACAN:

ACA1_095670

TET:	TTHERM_00332200 TTHERM_00825650

PTM:	GSPATT00036991001 GSPATT00036992001

PTI:	PHATRDRAFT_20192(D-LCR)

FCY:	FRACYDRAFT_207550

TPS:	THAPSDRAFT_42965

AAF:	AURANDRAFT_54174

PIF:	PITG_02245 PITG_02246

PSOJ:

PHYSODRAFT_284590 PHYSODRAFT_310261

BLAC:

94351685(CCR75_007958)

SPAR:

SPRG_04733

TCR:

504151.60

LMA:	LMJF_23_0810

LIF:	LINJ_23_0980

LDO:	LDBPK_230980

LMI:	LMXM_23_0810

LMAT:

92516037(LSCM1_06093)

LBZ:	LBRM_23_0900

LPAN:

LPMP_230960

LOI:	92360625(LSCM4_04710)

LEIS:

94180790(GH5_05415)

LEIN:

94189870(JIQ42_06253)

PHET:

94290905(JKF63_04856)

NGR:	NAEGRDRAFT_69307

GTT:	GUITHDRAFT_104792

» show all

Reference

1 [PMID:19586914]

Authors

Engqvist M, Drincovich MF, Flugge UI, Maurino VG

Title

Two D-2-hydroxy-acid dehydrogenases in Arabidopsis thaliana with catalytic capacities to participate in the last reactions of the methylglyoxal and beta-oxidation pathways.

Journal

J Biol Chem 284:25026-37 (2009)
DOI:10.1074/jbc.M109.021253

Sequence

[ath:AT4G36400]

Reference

2 [PMID:15070399]

Authors

Achouri Y, Noel G, Vertommen D, Rider MH, Veiga-Da-Cunha M, Van Schaftingen E

Title

Identification of a dehydrogenase acting on D-2-hydroxyglutarate.

Journal

Biochem J 381:35-42 (2004)
DOI:10.1042/BJ20031933