KEGG ENZYME: 1.3.1.58

ENZYME: 1.3.1.58

Entry

EC 1.3.1.58                 Enzyme

Name

2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase

Reaction(IUBMB)

cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate + NAD+ = 2,3-dihydroxy-p-cumate + NADH + H+ [RN:R05240]

Reaction(KEGG)

R05240

Substrate

cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate [CPD:C06579];
NAD+ [CPD:C00003]

Product

2,3-dihydroxy-p-cumate [CPD:C06580];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

Involved in the p-cymene degradation pathway in Pseudomonas putida.

History

EC 1.3.1.58 created 2000

Pathway

ec00622

Xylene degradation

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K10620

2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase

Genes

RBD:

ALSL_1090

PPF:

Pput_2895

PPX:	T1E_4251(cmtB)

PMON:

X969_10860

PMOT:

X970_10515

PASI:

LG197_17380

SPOI:

IMCC21906_02718

STAW:

NCG89_14260

ZAL:	AZF00_03850

GBI:	PG2T_14360

BAEN:

L3V59_37720

BXE:

Bxe_A3553

BXB:

DR64_1252

PFIB:

PI93_021415

THAU:

C4PIVTH_4368(cmtB)

BRK:	CWS35_25075

BARH:

WN72_35385

BGK:	IC762_14185

MON:	G8E03_15205

NRE:	BES08_18555

SMAZ:

LH19_27435

SWI:

Swit_1755

SPHD:

HY78_16810

RDI:	CMV14_03925

SNAP:

PQ455_10980

BACI:

B1NLA3E_14005

VIG:	BKP57_09430

RUE:	DT065_15135

EFF:	skT53_02000

MMAN:

MMAN_42600

MSAK:

MSAS_43610(benD)

MCOO:

MCOO_07700

MHAS:

MHAS_04024(fabG_14)

MANY:

MANY_01920

MAUS:

JN090_26180

ROP:	ROP_46310(cmtB)

RRZ:	CS378_10920

RKO:	JWS14_14225

ROZ:	CBI38_27950

RPSK:

JWS13_02060

RHOU:

KZJ41_22835

RHOJ:

JVH1_23285

RHJS:

OYT95_25020

SALS:

SLNWT_6904

SCZ:	ABE83_02000

FSY:	FsymDg_2035

AMQ:	AMETH_1184

AACD:

LWP59_08670 LWP59_25390

PSEQ:

AD006_28380

PECQ:

AD017_28770

PBRO:

HOP40_30830

PPEL:

H6H00_18655

PMAD:

BAY61_11505

PARN:

NBH00_20070

PARQ:

DSM112329_00839(fabG_2)

» show all

Reference

1 [PMID:8631713]

Authors

Eaton RW.

Title

p-Cumate catabolic pathway in Pseudomonas putida Fl: cloning and characterization of DNA carrying the cmt operon.

Journal

J Bacteriol 178:1351-62 (1996)
DOI:10.1128/JB.178.5.1351-1362.1996

Sequence

[ppf:Pput_2895]

Other DBs

ExplorEnz - The Enzyme Database:

1.3.1.58

IUBMB Enzyme Nomenclature:

1.3.1.58

ExPASy - ENZYME nomenclature database:

1.3.1.58

UM-BBD (Biocatalysis/Biodegradation Database):

1.3.1.58

BRENDA, the Enzyme Database:

1.3.1.58

CAS:	176591-33-6

LinkDB

DBGET integrated database retrieval system