KEGG   ENZYME: 1.4.1.19
Entry
EC 1.4.1.19                 Enzyme                                 
Name
tryptophan dehydrogenase;
NAD(P)+-L-tryptophan dehydrogenase;
L-tryptophan dehydrogenase;
L-Trp-dehydrogenase;
TDH
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor
Sysname
L-tryptophan:NAD(P)+ oxidoreductase (deaminating)
Reaction(IUBMB)
L-tryptophan + NAD(P)+ + H2O = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+ [RN:R00675 R00676]
Reaction(KEGG)
R00675 R00676;
(other) R00145 R00146
Substrate
L-tryptophan [CPD:C00078];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
(indol-3-yl)pyruvate [CPD:C00331];
NH3 [CPD:C00014];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Activated by Ca2+.
History
EC 1.4.1.19 created 1989
Reference
1
  Authors
Vackova K, Mehta A, Kutacek M.
  Title
Tryptophan aminotransferase and tryptophan dehydrogenase - activities in some cell compartments of spinach leaves - the effect of calcium-ions on tryptophan dehydrogenase.
  Journal
Biol Plant 27:154-158 (1985)
Other DBs
ExplorEnz - The Enzyme Database: 1.4.1.19
IUBMB Enzyme Nomenclature: 1.4.1.19
ExPASy - ENZYME nomenclature database: 1.4.1.19
BRENDA, the Enzyme Database: 1.4.1.19
CAS: 94047-13-9
LinkDB

DBGET integrated database retrieval system