KEGG   ENZYME: 1.5.1.39
Entry
EC 1.5.1.39                 Enzyme                                 
Name
FMN reductase [NAD(P)H];
FRG
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
FMNH2:NAD(P)+ oxidoreductase
Reaction(IUBMB)
FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+ [RN:R05705 R05706]
Reaction(KEGG)
R05705 R05706
Substrate
FMNH2 [CPD:C01847];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
FMN [CPD:C00061];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Contains FMN. The enzyme can utilize NADH and NADPH with similar reaction rates. Different from EC 1.5.1.42, FMN reductase (NADH) and EC 1.5.1.38, FMN reductase (NADPH). The luminescent bacterium Vibrio harveyi possesses all three enzymes [1]. Also reduces riboflavin and FAD, but more slowly.
History
EC 1.5.1.39 created 2011
Pathway
ec00740  Riboflavin metabolism
ec01100  Metabolic pathways
Orthology
K19286  FMN reductase [NAD(P)H]
Genes
EBT: EBL_c27760
KCY: RIN60_12660
LAX: APT61_15525
LEI: C2U54_11965
LEH: C3F35_04505
LEE: DVA44_16630
LER: GNG29_07170
LEA: GNG26_06810
LPNU: KQ929_14020
LEY: DVA43_10740
SCOL: KFZ77_15445
SMAF: D781_3978
SRZ: AXX16_1164
SERM: CLM71_20450
SOF: NCTC11214_02427(nfrA2)
SRHZ: FO014_13125
GQU: AWC35_15390
CARU: P0E69_22615
NIG: C1N62_17695
ECA: ECA0351
PATR: EV46_01875
PATO: GZ59_03810
PCT: PC1_0338
PCC: PCC21_003520
PCV: BCS7_01755
PWA: Pecwa_0381
PPAR: A8F97_16530
PEC: W5S_0391
PWS: A7983_09905
PPOA: BJK05_18485
PBRA: B5S52_20075
PPUJ: E2566_01980
PARI: I2D83_20165
PAQU: DMB82_0001645
PVZ: OA04_03910
PPAV: LOZ86_20040
PQU: IG609_002000
PPOO: LW347_02040
PCAC: OI450_02440
PACB: M9782_04060
PARL: PEC302110_36360
PPEU: DUT67_20130
DDC: Dd586_0336
DZC: W909_01750
CED: LH89_10405
DFN: CVE23_01850
DAQ: DAQ1742_00432(nfrA)
DIC: Dpoa569_0003639
DLC: O1Q98_09635
DDA: Dd703_3602
LBQ: CKQ53_06870
LPOP: I6N93_15335
ETA: ETA_14360
EPY: EpC_15110
EPR: EPYR_01625
ERJ: EJP617_31920
EPE: CI789_06245
ERWI: GN242_11750
ERP: LJN55_13685
EPI: Q3V30_10205
ERWE: GKQ23_14540
ETO: RIN69_01120
EGE: EM595_1786(nfrA2)
PAM: PANA_4101(ycnD)
PLF: PANA5342_p10256(nfsA)
PAJ: PAJ_p0190(ycnD)
PAQ: PAGR_p187
PVA: Pvag_pPag30453(nfsA)
PAGG: AL522_01420
PANT: PSNIH1_13335
PANP: PSNIH2_08275
PAGC: BEE12_21095
PSTW: DSJ_26140
PALH: B1H58_17560
PANS: FCN45_09600
PEY: EE896_19045
PDIS: D8B20_08360
PER: LAC65_07360
PJI: KTJ90_19795
PANO: OJ965_00620
KPIE: N5580_09200
PALF: K6R05_18485
PANE: P6287_09440
PAMT: IAI47_19540
PANZ: NR302_09465
PGZ: C2E15_10365
PCD: C2E16_10390
MINT: C7M51_01259(nfrA2)
MTHI: C7M52_01487(nfrA2)
MHAN: K6958_10475
PAY: PAU_03550(nfsA)
PDW: BV82_3628
PTK: EXN22_17190
MOW: RNZ41_04295
MORK: MOXK02_12670
MORX: MOXK23_07490
SZH: K0H63_09580
PAGI: ABHF91_00260 ABHF91_04495
CDIZ: CEDIAZO_02661(nfrA2)
NWE: SAMEA3174300_1074(nfrA2)
NBL: GJV52_11820
NZO: SAMEA4504057_1390(nfrA2)
NCI: NCTC10296_01936(nfrA1)
NANI: NCTC12227_00606(nfrA2)
NWD: H3L96_09525
NSG: H3L94_11705
NMUS: H7A79_1068
NDN: H3L92_03830
NWX: CGZ65_06140
NDU: LVJ88_06185
NAW: LVJ86_06230
PTES: JQU52_06960
USU: LVJ78_06440
UTE: LVJ83_06975
CCAH: DWG20_09145
CVI: CV_3500(nfsA)
CVC: BKX93_08250
CHRO: CXB49_04045
CHRI: DK842_02420
CHRB: DK843_07900
CRZ: D1345_15760
CHRM: FYK34_11905
CHAE: CH06BL_12120
PSE: NH8B_0873(nfsA)
AMAH: DLM_2982
AQS: DKK66_12120
VOX: LCH97_17575
CFON: HZU75_10885
LMIR: NCTC12852_01584(nfrA2)
BHZ: ACR54_01072(nfrA2)
BPDZ: BBN53_16450
BGM: CAL15_22185
DTS: BI380_30420
OAL: NB647_05495
FKU: FGKAn22_17960
AIQ: Azoinq_08675
FLE: KI610_13765
BROS: QUH67_10360
VGO: GJW-30_1_00134(nfrA2)
RHZ: RHPLAN_09810
RBM: TEF_03350
RPOP: K1718_07395
JAN: Jann_3965
RPON: G3256_11725
RFU: ROLI_016420(nfrA2)
SULI: C1J05_16275
SUSQ: K3756_13025
TOM: BWR18_17200
RPHC: RZ517_05115
RRL: RZS32_002305
GCE: KYE46_03260
GYJ: AADW23_02215
RFL: Rmf_12210
SRF: LHU95_13530
ELIO: KO353_07770
SHUM: STHU_12800
SVC: STVA_36340
THAR: T8K17_02870
SDL: Sdel_1072
SBA: Sulba_1190
SMUL: SMUL_3050
SHAL: SHALO_2816
SULS: Sdiek1_2822
SULJ: SJPD1_2729
SULT: FA592_06415
ANT: Arnit_1586
AVP: AVENP_1774(rdxA)
ARC: ABLL_0970
AHS: AHALO_0021(rdxA)
AMAR: AMRN_0020(rdxA)
ACAA: ACAN_0019(rdxA)
AMOL: AMOL_0022(rdxA)
HEBR: AEBR_1383(rdxA)
AANA: AANAER_2189(rdxA)
OBT: OPIT5_26535
TPHG: FUT81_02860
SPER: EW093_04175
SCC: Spico_1094
BOA: Bovatus_01450(nfrA2_2)
BCEL: BcellWH2_01611(nfrA2_2)
BIS: DXK01_000135
PCOP: I6J50_10355
PCAG: NCTC12856_00837(nfrA2_1)
PARY: A4V02_04830
MGOD: E7746_03670
DUN: FDZ78_03220
DUQ: E7745_13980
PII: NF347_13605
BVS: BARVI_11570
COPR: Cop2CBH44_12120(nfrA2)
CFAS: Cfast33896_26020(nfsA)
PDT: Prede_2711
PJE: CRM71_14205
POC: NCTC13071_02248(nfrA2)
ALQ: C7Y71_010890
ALD: GFH31_09690
AIT: AI2BBH_18350(nfrA2)
BSU: BSU03860(ycnD)
BSR: I33_0443
BSL: A7A1_3092
BSH: BSU6051_03860(ycnD)
BSY: I653_01960
BSUT: BSUB_00437(ycnD)
BSUL: BSUA_00437(ycnD)
BSUS: Q433_02300
BSO: BSNT_06728(ycnD)
BSN: BSn5_13535
BSQ: B657_03860(ycnD)
BSX: C663_0379(ycnD)
BSP: U712_02005
BSS: BSUW23_01995(ycnD)
BST: GYO_0602
BIT: BIS30_12510
BLI: BL01854(nfrA2)
BLD: BLi00470(nfrA1)
BLH: BaLi_c04910(ycnD)
BAY: RBAM_004110(nfsA)
BAQ: BACAU_0347(ycnD)
BYA: BANAU_0347(ycnD)
BQY: MUS_0374(nfrA1)
BAMP: B938_01820
BAML: BAM5036_0370(nfrAB)
BAMA: RBAU_0384(nfrAB)
BAMN: BASU_0369(nfrAB)
BAMB: BAPNAU_0352(ycnD)
BAMT: AJ82_02265
BAMY: V529_03720(ycnD)
BMP: NG74_00388(nfrA2)
BAO: BAMF_0354(ycnD)
BAZ: BAMTA208_01795(ycnD)
BQL: LL3_00369(ycnD)
BXH: BAXH7_00372(ycnD)
BAMI: KSO_017635
BAMC: U471_03760
BAMF: U722_02085
BSIA: CWD84_19970
BAE: BATR1942_20640
BSON: S101395_04550
BHT: DIC78_08030
BMOJ: HC660_04280(nfrAB)
BTEQ: G4P54_02120
BIQ: AN935_02000
BSTR: QI003_02190(nfsA)
BGY: BGLY_0483(nfrA2)
BWH: A9C19_08475
BCAB: EFK13_02375(nfsA)
BRY: M0696_02230(nfsA)
BJS: MY9_0402
BACP: SB24_07760
BACB: OY17_04705
BACY: QF06_00900
BACL: BS34A_04440(ycnD)
BALM: BsLM_0407
BACS: AUL54_08795
BACQ: DOE78_02430
BAFC: K3G25_19485(nfsA)
BCO: Bcell_0803
BCIR: C2I06_12235 C2I06_17345
NTX: NQZ71_06260
NIL: L8T27_015490
NTGC: AB3U99_17985
BMQ: BMQ_3033
BMD: BMD_3058
BMH: BMWSH_2145(ycnD)
BMEG: BG04_5560(nfrA2)
BEO: BEH_12430
BHA: BH2953
BLE: BleG1_0728
SHUA: PQ477_12105
BGI: BGM20_17005
BPF: BpOF4_02425
LYP: MTP04_31420(nfrA2)
TAP: GZ22_00705
TAID: KS242_01955
PASA: BAOM_2239
PRD: F7984_10715
NDT: L1999_12815
MEKU: HUW50_25285
MLIT: KDJ21_015770
MENL: MVE64_03065
MEBZ: LPC09_14975
MRL: WCV66_14435
ALKL: MM271_18865(nfsA)
SLZ: B5P37_08160
LMO: lmo2111
LMN: LM5578_2314
LMY: LM5923_2265
LMT: LMRG_01265
LMOC: LMOSLCC5850_2176
LMOE: BN418_2542
LMOB: BN419_2548
LMOD: LMON_2185
LMOW: AX10_04815
LMOQ: LM6179_02886
LMR: LMR479A_2222(nfrA)
LMOM: IJ09_14380
LMF: LMOf2365_2144
LMC: Lm4b_02133
LMOG: BN389_21420(nfrA2)
LMP: MUO_10830
LMOL: LMOL312_2127
LMOJ: LM220_14556
LMOZ: LM1816_17325
LMOX: AX24_08420
LMH: LMHCC_0435
LMQ: LMM7_2213(nfsA)
LML: lmo4a_2172
LMG: LMKG_00206
LMS: LMLG_0315
LMJ: LMOG_01108
LMW: LMOSLCC2755_2175
LMX: LMOSLCC2372_2179
LMZ: LMOSLCC2482_2173
LMON: LMOSLCC2376_2068
LMOS: LMOSLCC7179_2087
LMOO: LMOSLCC2378_2139
LMOY: LMOSLCC2479_2176
LMOT: LMOSLCC2540_2208
LMOA: LMOATCC19117_2133
LMOK: CQ02_10940
LMV: Y193_04965
LIN: lin2216
LWE: lwe2130
LSG: lse_2100
LIV: LIV_2102
LII: JL52_11035
LIW: AX25_11215
LIA: JL58_11210
LIO: JL53_11710
LWI: UE46_04395
LMAR: LAX80_010345
LNW: OTR81_00645
GOT: AXE85_06405
GMO: NCTC11323_00788(nfrA2)
GEQ: CG018_00025 CG018_08330
GSA: FOC50_00550
GHA: NCTC10459_00998(nfrA2)
PLV: ERIC2_c22420(nfrA)
PSAB: PSAB_09310
PDU: PDUR_10515
PBD: PBOR_29830
PGM: PGRAT_26850
POD: PODO_25615
PAEN: P40081_31390
PAEF: R50345_25550
PAEQ: R50912_28210
PSTE: PSTEL_10490
PAEA: R70723_27045
PAEE: R70331_26140
PAEH: H70357_28885
PAEJ: H70737_25355
PRI: PRIO_5617(nfrA2)
PSON: JI735_03070
PSWU: SY83_09875
PDH: B9T62_26040
PSOP: KP014_13050
PTRI: KDC22_27365
PTJ: JRJ22_24115
PAUB: PUR_20520
ANX: ACH33_05035
ATHE: K3F53_13870
PABS: JIR001_21310(nfrA2)
LME: LEUM_1770
LMM: MI1_07670
LMK: LMES_1537
LCI: LCK_01452
LKI: LKI_07275
LEC: LGMK_04870
LCN: C270_01495
LGS: LEGAS_0410
LGE: C269_01980
LLF: BCR17_05385
LGC: A9176_03925
LSU: A6B45_08470
LPSE: FGL85_04270
LKN: FGL74_03320
WCB: AO080_04595
ECAS: ECBG_01384
EGA: AL523_06375
ESS: ATZ33_02170 ATZ33_05405
EGV: EGCR1_05905
EAV: EH197_15855
ESG: EsVE80_23160
ERAF: J9537_08145
EIE: ENLAB_20930(nfnB_3)
EDS: PML78_09085
EMS: P3T75_01310
ENI: CXM95_01300
ERX: ATZ35_14050
VAH: G7081_05190
CAC: CA_C0718
CAE: SMB_G0733(nfrA2)
CAY: CEA_G0729
CBE: Cbei_2778
CBZ: Cbs_2778
CBEI: LF65_02693
CSR: Cspa_c24470(nfrA2)
CSB: CLSA_c18180(nfrA)
CSQ: CSCA_2118
CCK: Ccar_03960 Ccar_12565
CEU: A7L45_20090
CDRK: B9W14_08975
CDY: F3K33_14040
CGAS: J1C67_17845(nfsA)
CMAH: C1I91_02900
CNN: CNEO_2181(nfrA)
CGEL: psyc5s11_17540 psyc5s11_24230
CTAG: LL095_09030 LL095_09085
CINT: HZF06_18035
OKO: Ruko_12510
DSY: DSY4001
DHD: Dhaf_1363
DDH: Desde_1288
DDL: Desdi_1073
AWO: Awo_c31780(ycnD)
LXA: OW255_12895
ACEL: acsn021_01520
AHB: bsdtb5_02480
TEB: T8CH_3034(nfrAB)
CST: CLOST_2291(ycnD)
HPRF: HLPR_06340(nfsA_1)
GBX: SANA_06100 SANA_20150
TIS: P3962_14880
PUF: UFO1_1217
ERL: AOC36_02845
MAMP: MAMA39_02190
MTAU: JS510_02855
MMIR: HLA87_01615
MMIO: HLA92_02815
MPHE: HGG69_01240
MCM: MCAL160_0118(nfnB)
MAA: MAG4830
MAL: MAGa5300
MBV: MBOVPG45_0332
MBH: MMB_0518
MBI: Mbov_0557(nfsA)
MBQ: K668_02595
MBOV: MBVG596_0774
MPHI: EG856_00230
MPE: MYPE6430(MYPE6430)
MIW: EER00_01505
TIO: INP52_06185
LCAL: ATTO_03810(nfrA2)
ERZ: ER308_20105
CPL: Cp3995_0072(noxC)
CPP: CpP54B96_0074(noxC)
CPK: CP1002_00355
CPX: CPI19_00355
COD: Cp106_0070(noxC)
CPSE: CPTA_00595
CPSU: CPTB_00937
CPSF: CPTC_00598
CUC: CULC809_00117
CUS: CulFRC11_0113(noxC)
NBR: O3I_010610
SALA: ESZ53_04855
LEU: Leucomu_08020
SRO: Sros_4170
AHW: NCTC11636_02565(nfrA2)
ACAP: MANAM107_18800
ALIL: D5R93_09225
LBA: Lebu_0572
LOT: AXF11_01915
LEQ: BCB68_06900
LHF: JCM16775_0682
LSZ: JCM16776_0544
LHG: JMUB5056_0530
LTE: JMUB4039_1795
LWD: JCM16777_0562
LRUG: AB8B22_06850
LMES: AB8B23_03505
LALA: AB8B28_03255
LGO: JCM16774_0985 JCM16774_0986
STR: Sterm_0690
SMF: Smon_1230
SNS: VC03_01295
HBU: Hbut_1016
PFM: Pyrfu_1980
PDL: Pyrde_1861
NIR: NSED_03660
NKR: NKOR_03635
NID: NPIRD3C_1535
NIN: NADRNF5_1431
NIW: Nisw_01265
NCL: C5F47_05515
NOX: C5F49_05390
NUE: C5F50_05335
 » show all
Reference
1  [PMID:6981058]
  Authors
Watanabe H, Hastings JW
  Title
Specificities and properties of three reduced pyridine nucleotide-flavin mononucleotide reductases coupling to bacterial luciferase.
  Journal
Mol Cell Biochem 44:181-7 (1982)
DOI:10.1007/bf00238506
Other DBs
ExplorEnz - The Enzyme Database: 1.5.1.39
IUBMB Enzyme Nomenclature: 1.5.1.39
ExPASy - ENZYME nomenclature database: 1.5.1.39
BRENDA, the Enzyme Database: 1.5.1.39
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