ENZYME: 2.3.1.155
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Entry
EC 2.3.1.155 Enzyme
Name
acetyl-CoA C-myristoyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
myristoyl-CoA:acetyl-CoA C-myristoyltransferase
Reaction(IUBMB)
myristoyl-CoA + acetyl-CoA = CoA + 3-oxopalmitoyl-CoA [RN:
R03991
]
Reaction(KEGG)
R03991
Reaction
Substrate
myristoyl-CoA [CPD:
C02593
];
acetyl-CoA [CPD:
C00024
]
Product
CoA [CPD:
C00010
];
3-oxopalmitoyl-CoA [CPD:
C05259
]
Comment
A peroxisomal enzyme involved in branched chain fatty acid beta-oxidation in peroxisomes. It differs from EC
2.3.1.176
(propanoyl-CoA C-acyltransferase) in not being active towards 3-oxopristanoyl-CoA.
History
EC 2.3.1.155 created 2000
Reference
1 [PMID:
6117552
]
Authors
Miyazawa S, Furuta S, Osumi T, Hashimoto T, Ui N.
Title
Properties of peroxisomal 3-ketoacyl-coA thiolase from rat liver.
Journal
J Biochem (Tokyo) 90:511-9 (1981)
DOI:
10.1093/oxfordjournals.jbchem.a133499
Other DBs
ExplorEnz - The Enzyme Database:
2.3.1.155
IUBMB Enzyme Nomenclature:
2.3.1.155
ExPASy - ENZYME nomenclature database:
2.3.1.155
BRENDA, the Enzyme Database:
2.3.1.155
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integrated database retrieval system