| Entry |
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| Name |
decylhomocitrate synthase;
2-decylhomocitrate synthase;
3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acylating)
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| Class |
Transferases;
Acyltransferases;
Acyl groups converted into alkyl groups on transfer
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| Sysname |
dodecanoyl-CoA:2-oxoglutarate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)
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| Reaction(IUBMB) |
dodecanoyl-CoA + H2O + 2-oxoglutarate = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA [RN: R03859]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
(3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate [CPD: C04529];
CoA [CPD: C00010]
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| Comment |
Decanoyl-CoA can act instead of dodecanoyl-CoA, but 2-oxoglutarate cannot be replaced by oxaloacetate or pyruvate.
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| History |
EC 2.3.3.4 created 1976 as EC 4.1.3.29, transferred 2002 to EC 2.3.3.4
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| Reference |
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| Authors |
Mahlen A. |
|---|
| Title |
Purification and some properties of 2-decylhomocitrate synthase from Penicillium spiculisporum. |
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| Journal |
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| Reference |
2 |
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| Authors |
Brandage S, Dahlman O, Lindqvist B, Maahlen A, Morch L. |
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| Title |
Absolute configuration and enantiospecific synthesis of spiculisporic acid. |
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| Journal |
Acta Chem Scand 38B:837-844 (1984) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.3.3.4 |
| ExPASy - ENZYME nomenclature database: | 2.3.3.4 |
| BRENDA, the Enzyme Database: | 2.3.3.4 |
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| LinkDB |
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