Entry
Name
bacteriochlorophyll a synthase;
bchG (gene name)
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
geranylgeranyl-diphosphate:bacteriochlorophyllide-a geranylgeranytransferase
Reaction(IUBMB)
geranylgeranyl diphosphate + bacteriochlorophyllide a = geranylgeranyl-bacteriochlorophyllide a + diphosphate [RN:
R11514 ]
Reaction(KEGG)
Substrate
geranylgeranyl diphosphate [CPD:
C00353 ];
bacteriochlorophyllide a [CPD:
C18155 ]
Product
geranylgeranyl bacteriochlorophyllide a [CPD:
C21217 ];
diphosphate [CPD:
C00013 ]
Comment
The enzyme catalyses the addition of a geranylgeranyl hydrophobic chain to bacteriochlorophyllide a via an ester bond with the 17-propionate residue. The side chain is later modified to a phytyl chain, resulting in bacteriochlorophyll a.
History
EC 2.5.1.133 created 2016
Pathway
ec01110 Biosynthesis of secondary metabolites
Orthology
K04040 chlorophyll/bacteriochlorophyll a synthase
Genes
CSAT : 104711728 104781015 104791427
BNA : 106349059 106367679 106402842 106437912
HSYR : 120142838 120188285
GMX : 100779167 100787459 100800348
GSJ : 114389040 114397459 114419087
TPRA : 123888906 123890625
ADU : 107475314 107484985 110277958
AIP : 107625774 107625777 107639575
AHF : 112728023 112728025 112743675 112750534 112797059
LANG : 109325993 109361302
MSYL : 126591890 126619596
PXB : 103930527 103940196 103965133
PCOX : 137722379 137745644
CMAX : 111466211 111478261
CMOS : 111438198 111453218
CPEP : 111781117 111803248
PALZ : 118037508 118048500
CILL : 122277210 122278081
NTA : 107781977(CHLG) 107794961(CHLG)
OEU : 111377928 111407076 111408022
SSPL : 121763746 121798078
AEW : 130773083 130782421 130794251
ATRI : 130800030 130804760
PSOM : 113313327 113313440 113323264 113338745
TAES : 123052740 123129081 123181728
PVIR : 120673104 120709305
PAUA : 133885364 133928728
ZOF : 121980436 121984344 122040898 122045407
ACAK : 137942446 137965975
SMO : SELMODRAFT_423983 SELMODRAFT_424937
MPP : MICPUCDRAFT_33362(CHLG)
FCY : FRACYDRAFT_223502(ChlG)
EHX : EMIHUDRAFT_421924 EMIHUDRAFT_430815
GTT : GUITHDRAFT_160205(CHLG)
TFRI : Thiofri_01157(bchG)
LIM : L103DPR2_01006(cyoE)
LIH : L63ED372_00662(cyoE)
MAQU : Maq22A_c01660(ubiA)
MMES : MMSR116_22230(chlG)
RLI : RLO149_p940670(bchG)
LVS : LOKVESSMR4R_03328(ubiA)
CTM : Cabther_A1763 Cabther_B0037
CVL : J8C06_01225(chlG) J8C06_05575 J8C06_11270(chlG)
CHLO : J8C02_08665(chlG) J8C02_11935(chlG)
PSPC : Strain318_000120(chlG)
CTE : CT1270(chlG) CT1610(bchG)
CLZ : BIU88_02640 BIU88_04600
CPH : Cpha266_0583 Cpha266_1449
CPB : Cphamn1_0602 Cphamn1_1089
PROC : Ptc2401_00566 Ptc2401_00764
PRS : B9H02_02515 B9H02_04620
PROS : CHL67_04500 CHL67_08975
PROW : OO006_07960(chlG) OO006_10815(chlG)
PROI : OO005_07345(chlG) OO005_09850(chlG)
SYR : SynRCC307_0577(chlG)
SYX : SynWH7803_1776(chlG)
SYH : Syncc8109_1904(chlG)
SYNW : SynWH8103_01908(chlG)
TVN : NIES2134_114550(chlG)
SYP : SYNPCC7002_A0548(chlG)
SYNN : NIES970_10640(chlG)
MVZ : myaer102_54720(chlG)
PAGH : NIES204_39460(chlG)
PRUN : PCC7821_04701(CHLG)
NCW : NIES2107_37180(chlG)
NSPH : BDGGKGIB_00678(menA_1)
CALN : NIES2098_53920(chlG)
MDP : NIES3275_59010(chlG)
STAN : STA3757_15840(chlG)
CHL : Chy400_0145 Chy400_2251
CALL : OZ401_001677(chlG) OZ401_002285 OZ401_002374(chlG) OZ401_003162
» show all
Taxonomy
Reference
Authors
Oster U, Bauer CE, Rudiger W.
Title
Characterization of chlorophyll a and bacteriochlorophyll a synthases by heterologous expression in Escherichia coli.
Journal
Reference
Authors
Addlesee HA, Fiedor L, Hunter CN.
Title
Physical mapping of bchG, orf427, and orf177 in the photosynthesis gene cluster of Rhodobacter sphaeroides: functional assignment of the bacteriochlorophyll synthetase gene.
Journal
Sequence
Reference
Authors
Garcia-Gil LJ, Gich FB, Fuentes-Garcia X
Title
A comparative study of bchG from green photosynthetic bacteria.
Journal
Reference
Authors
Saga Y, Hirota K, Harada J, Tamiaki H
Title
In Vitro Enzymatic Activities of Bacteriochlorophyll a Synthase Derived from the Green Sulfur Photosynthetic Bacterium Chlorobaculum tepidum.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.5.1.133
LinkDB
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