KEGG   ENZYME: 2.7.1.168
Entry
EC 2.7.1.168                Enzyme                                 
Name
D-glycero-alpha-D-manno-heptose-7-phosphate kinase;
D-alpha-D-heptose-7-phosphate kinase;
hdda (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:D-glycero-alpha-D-manno-heptose 7-phosphate 1-phosphotransferase
Reaction(IUBMB)
D-glycero-alpha-D-manno-heptose 7-phosphate + ATP = D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + ADP [RN:R09770]
Reaction(KEGG)
R09770
Substrate
D-glycero-alpha-D-manno-heptose 7-phosphate [CPD:C19878];
ATP [CPD:C00002]
Product
D-glycero-alpha-D-manno-heptose 1,7-bisphosphate [CPD:C19879];
ADP [CPD:C00008]
Comment
The enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly of S-layer glycoprotein in Gram-positive bacteria. The enzyme is specific for the alpha-anomer.
History
EC 2.7.1.168 created 2010
Pathway
ec00541  Biosynthesis of various nucleotide sugars
ec01100  Metabolic pathways
Orthology
K07031  D-glycero-alpha-D-manno-heptose-7-phosphate kinase
Genes
YPB: YPTS_1055
YPQ: DJ40_1348
YPU: BZ21_254
YPR: BZ20_1035
YPC: BZ23_530
YMO: HRD69_10995
YAS: N0H69_17365
PLU: plu4822(wblW)
PLUM: A4R40_23985
STEZ: ACEPA4_02685
LSOL: GOY17_03450
LHX: LYSHEL_08800
LCAS: LYSCAS_08800
THES: FHQ07_06205
TBV: H9L17_06865
VAF: D1115_23010
VSR: Vspart_00200
VZI: G5S32_14885
VJP: NP165_18370
VRU: RND59_05090
PGB: H744_1c0473 H744_2c2398
PGH: FH974_09840
PPB: PPUBIRD1_1475
PEN: PSEEN2467
PBZ: GN234_10450
PMUY: KSS95_17170
PORY: EJA05_20065
PWZ: J7655_08610
PSIH: LOY51_19410
PASI: LG197_25600
PSKP: KU43P_15440
PALL: UYA_23045
PKH: JLK41_16270
PAGR: E2H98_17350
SBB: Sbal175_1477
PSHO: KQ246_01935
AMAG: I533_13340
CEB: B0D95_15720
CENO: CEAn_00649
ASIP: AQUSIP_17830(hddA)
METL: U737_03390
MEEP: JWZ98_02680
MMOB: F6R98_01280 F6R98_19120
MEIN: methR_P2381
MESL: KKZ03_15230
HTR: EPV75_08915
TVI: Thivi_4045
HCH: HCH_06166
HAHE: ENC22_26595
HAHH: O5O45_29400
TOL: TOL_2206
TOR: R615_06625
ENW: MJO57_17205
CHRM: FYK34_20160
REU: Reut_A0720
CUP: BKK80_17040
CUU: BKK79_15315
BMA: BMA2296(hddA)
BMV: BMASAVP1_A0532(hddA)
BML: BMA10229_A1068(hddA)
BMN: BMA10247_2174(hddA)
BMAZ: BM44_1067
BMAL: DM55_1488
BMAE: DM78_2666
BMAQ: DM76_1466
BMAI: DM57_1071
BMAF: DM51_1937
BMAB: BM45_2462
BPS: BPSL2796(wcbL)
BPM: BURPS1710b_3292(wcbL)
BPL: BURPS1106A_3278
BPD: BURPS668_3243
BPR: GBP346_A3421
BPSE: BDL_2649
BPSM: BBQ_513
BPSU: BBN_641
BPSD: BBX_1047
BPZ: BP1026B_I0514(wcbL)
BPQ: BPC006_I3326
BPK: BBK_2134
BPSH: DR55_1722
BPSA: BBU_2766
BPSO: X996_1362
BUT: X994_3360
BTD: BTI_920
BTHA: DR62_529
BCEW: DM40_4219
BLAT: WK25_23460
BSTL: BBJ41_08340
BARI: NLX30_31965
BAEN: L3V59_19725
BPLA: bpln_1g18350
BUZ: AYM40_03120 AYM40_03400
BCAI: K788_0007827
PHS: C2L64_13965
PMEG: FNZ07_18185
PACS: FAZ98_02525
PBON: QS306_10760
PPAL: AOC06_01770
PCOS: C2747_01695
PYT: PKF023_03470
POLK: PKF022_03500
PAPI: SG18_07840
TVL: FAZ95_17375
TCAR: U0034_03680
RSB: RS694_17775
RDP: RD2015_4052
ATER: MW290_21700 MW290_27360
HSE: Hsero_4413
HSZ: ACP92_22040
HFR: G5S34_23500
HEW: HBDW_45170
MASS: CR152_19255
AON: DEH84_17460
NET: Neut_0157
MEH: M301_2248
MBAT: BN1208_0905 BN1208_0916
MEU: ACJ67_08030
ARES: IWH25_01535
NIV: JY500_12300
REN: EF513_03810
MOH: IHQ72_18970
SFD: USDA257_c10760
RLT: Rleg2_5597
RLB: RLEG3_01580
RHN: AMJ98_PB00039
RPHA: AMC79_PA00039
RHX: AMK02_PB00038
REZ: AMJ99_PA00039
RJG: CCGE525_26860
RAD: CO657_35040
RII: FFM53_035125
RHID: FFM81_022900
RLN: J0663_28370
RBAN: J2J98_27900
RBW: RLCC275e_32010
RHIZ: QMO80_006022
SHIN: LHJ69_10175
BJA: blr5970(blr5970)
BRC: BCCGELA001_23760 BCCGELA001_25425
BOT: CIT37_24415
BRQ: CIT40_21825
BSYM: CIT39_21115
BDG: LPJ38_30125 LPJ38_31860
BQB: J4P68_0034315
BCOU: IC761_11755
BRAZ: LRP30_27525
BOW: NWE53_19495
MRD: Mrad2831_1227
MOR: MOC_1454
MPHY: MCBMB27_00831
METX: A3862_24530
METS: DK389_08185
METI: DK427_00615
MENS: LOK46_06400
MLG: CWB41_06520
DOY: JI749_13905
MECQ: MSC49_37250
MLUT: JET14_03495
AUB: LXB15_15190
MFLG: ABS361_22420
CAK: Caul_4922
CSE: Cseg_1876 Cseg_1877
CMB: CSW64_13090 CSW64_13095
CFH: C1707_06540
CAUL: KCG34_18330
BVC: CEP68_07765
BREV: E7T10_02320
BND: KWG56_04310 KWG56_04315
BIR: ACETKC_00030
AEX: Astex_2282
JAN: Jann_4245
KVL: KVU_0341(lmbP)
KVU: EIO_0807
RSU: NHU_00146
RHM: B5V46_02155
NRE: BES08_12530
SSAN: NX02_24820
SCH: Sphch_2708
SPRS: EGM87_12000
AZL: AZL_f00470
ALI: AZOLI_p60015
ABQ: ABAZ39_33030
ATI: AL072_31755
AZM: DM194_26760
AZZ: DEW08_29825
AZP: E6C67_04365
ADJ: ACIU1J_15940
NAO: Y958_28035
NCB: C0V82_26600
MGY: MGMSRv2__4176
MAGX: XM1_1802
MAGN: WV31_16785
FER: FNB15_03135 FNB15_03245
MAG: amb1073
MAGQ: MGMAQ_1158
APB: SAR116_0985
MGM: Mmc1_0617
HPUL: NCTC13154_01559
CJE: Cj1425c(hddA)
CJB: BN148_1425c(hddA)
CJJ: CJJ81176_1424
CJN: ICDCCJ07001_1356
CJS: CJS3_1518
CJEJ: N564_01422
CJEU: N565_01462
CJEN: N755_01459
CJEI: N135_01515
CJER: H730_08145
CJY: QZ67_01564(hddA)
CJQ: UC78_1366(hddA)
CJW: PJ18_07300
CJR: CJE1610
CJD: JJD26997_1759
CJZ: M635_02850
CJX: BN867_14020
CLR: UPTC16701_0316
CLM: UPTC16712_0314
CLN: UPTC3659_0326
CCF: YSQ_01735
CIS: CINS_0292
CAMR: CAQ16704_0315
CSM: CSUB8521_0327
CHV: CHELV3228_0216
CCUN: CCUN_1153
CLX: CLAN_0156
CHW: A2J15_004900
CAMZ: CVIC12175_0184
COJ: CORN_0313
CUX: CUP3940_1433
CARM: CARM_0281
CNV: CNZW441b_0360
CVU: CVULP_1507
CDEV: CIGN_0116
ANT: Arnit_2925
ALK: ALEK_0995
AMYT: AMYT_0706
HMR: Hipma_1693
GLO: Glov_0793
DMA: DMR_p1_00290
DAS: Daes_0075
DPI: BN4_12080
PPRF: DPRO_PA0008(hddA)
LIP: LIA008(mvaK1) LIC011(mvaK1)
LIR: LAW_10008 LAW_30012
DOL: Dole_1710
DAL: Dalk_0045 Dalk_1697
DAT: HRM2_28150
DTO: TOL2_C22230
DOV: DSCO28_03340 DSCO28_69630
DWD: DSCW_17180
DALK: DSCA_16630
DVR: Dvar_35890
DML: Dmul_12370
DLI: dnl_13350
DTI: Desti_0156 Desti_4186
DMP: FAK_14240
TCM: HL41_06285
APAU: AMPC_02950
SCL: sce0565 sce3746
SCU: SCE1572_03850 SCE1572_22545
CCRO: CMC5_014780 CMC5_049810
PAUU: E8A73_015170 E8A73_034250
MRM: A7982_01767 A7982_09688
BBA: Bd1027(lmbP)
BBAT: Bdt_0972(lmbP)
BBW: BDW_03545
BBAC: EP01_15225
BDQ: CIK05_03850
BDC: DOE51_04845
BDZ: DOM22_15170 DOM22_19045
BDK: HW988_14160 HW988_18085
BREY: MNR06_07585
BEX: A11Q_821
BMX: BMS_0715
HAX: BALOs_0673(hddA)
BSTO: C0V70_03945
PSTI: SOO65_05750
SBF: JCM31447_25540
PIJ: QEJ31_04455
SNG: SNE_A16710
OTE: Oter_3977
VBH: CMV30_09125
MTAR: DF168_01773(hddA)
ROO: G5S37_00860 G5S37_22820
VEG: SAMN05444156_2642
LCRE: Pla8534_46730(hddA)
AAGG: ETAA8_22160(hddA)
TTF: THTE_1816
GAW: V144x_54410(hddA)
ACAF: CA12_42420(hddA)
TPOL: Mal48_40710(hddA)
GES: VT84_07095(hddA_1) VT84_15600(hddA_2)
GOG: C1280_05615 C1280_17645
GMS: SOIL9_33210 SOIL9_49840
FTJ: FTUN_2609 FTUN_5819
ULI: ETAA1_15250(hddA)
TPLA: ElP_75810(hddA)
PBAP: Pla133_04300(hddA)
KST: KSMBR1_2293(mvk)
BPIT: BPIT_11870 BPIT_20170
HBS: IPV69_06525 IPV69_10385
VBC: C5Q97_20050
VAI: BU251_02245
TPI: TREPR_2396
TSK: HRI97_06125
OCK: EXM22_02760
TAZ: TREAZ_0677
LIOW: AB3N60_10110
ABA: Acid345_2431
ACA: ACP_0827
ABAS: ACPOL_2477
ADIN: H7849_01375
TPSC: RBB77_18795
CTM: Cabther_A1094
CVL: J8C06_06790
CHLO: J8C02_05310
SUS: Acid_0418 Acid_6718
PFER: IRI77_13950 IRI77_21095 IRI77_21585
ABAC: LuPra_03128 LuPra_04981
LUB: TBR22_A22050
GEX: GETHOR_18940
GET: QOZ81_002131
MSIL: METEAL_02470
MSEA: METESE_02530
GAU: GAU_0471
GPH: GEMMAAP_03085
GGR: HKW67_12705
GBA: J421_2375
BTH: BT_0474
BTHO: Btheta7330_02888(hddA_2)
BFG: BF638R_1442
BOA: Bovatus_04910(hddA_2)
PARC: CI960_06785
PGOL: K6V26_21085
PCOU: L6468_04005
PCOI: LK433_04715
SBAO: L6469_11235 L6469_11265 L6469_11305
PCLR: PC1C4_23790
ALD: GFH31_01600 GFH31_09970
AIT: AI2BBH_01740
AIU: NQ491_03835 NQ491_10960
DRC: G0Q07_10135
MCOS: GM418_21700
CPI: Cpin_3115
CHIH: GWR21_07425
COY: HF329_02890
CFIL: MYF79_22175
CHF: KTO58_06625
CSAC: SIO70_23830
CHIM: CK934_22435
NKO: Niako_2547
NSO: NIASO_09030
NIA: A8C56_12850
NYN: U0035_05260
FLA: SY85_01490
ARK: D6B99_15390
ARAC: E0W69_018550
FLN: FLA_6276
PSEG: D3H65_10785
PGIN: FRZ67_05010
PGO: FSB84_23220
FLS: GLV81_14335
FEI: K9M53_08240
FLP: LK994_12835
SEDT: TEGAF0_25510
THEO: IMW88_11165
CBAM: PIECOFPK_01326(hddA)
MDJ: LLH06_15000
SLI: Slin_4183
SRD: SD10_02775
SMON: AWR27_11760
SPIR: CWM47_28690
SPIK: EXU85_05945
SPIB: G8759_34665
STAE: HNV11_01635
SRHO: HH216_04355
SOQ: LQ777_21635
SFOL: H3H32_00445
SENF: GJR95_39740
RHOZ: GXP67_25005
MAQA: LAG90_13975
DFE: Dfer_4626
DSN: HWI92_22175
DYC: NFI80_14045
DFQ: NFI81_15175
DCN: MUK70_18680
DPF: ON006_30030
RSI: Runsl_0376
RUN: DR864_23850
RUP: DTQ70_14515
FAE: FAES_1442
RTI: DC20_21850
ADD: HUW48_23210
ASWU: HUW51_05125
CLIT: OQ292_00180
CHRW: KA713_13925
PRHO: PZB74_07530
TPEL: P0M28_13565
WIN: WPG_0814
KAN: IMCC3317_07720(hddA)
OHO: Oweho_0133
PAA: Paes_1742
RBAR: AWN76_008975
NDE: NIDE2328 NIDE3425(hddA)
NALL: PP769_09060 PP769_12640
NNEO: PQG83_03485 PQG83_20295
LFI: LFML04_1771
NLI: G3M70_02430
NVA: G3M78_06055 G3M78_07650
PPSC: EHS13_28200
PRZ: GZH47_12305
PALR: HGI30_17915
PHEX: L0M14_19150
ASOC: CB4_00632(hddA)
COHL: J4772_33165
AFX: JZ786_00205
ACUR: JZ785_20290
LLK: LLKF_2314
LLX: NCDO2118_2176
LLM: llmg_2347
LLR: llh_12025
LLN: LLNZ_12135
LLW: kw2_2126
EFAU: EFAU085_01996
CAC: CA_C3055
CAE: SMB_G3091(mvk)
CAY: CEA_G3061
CFER: D4Z93_01730
CRW: CROST_039030(hddA)
CFB: CLFE_008790(hddA)
CAUN: CLAUR_036230(hddA)
CNN: CNEO_3852
CGEL: psyc5s11_31730
RHER: EHE19_007360
RPAY: P0092_03715
FPA: FPR_02560
FAH: MTP37_04590
RUK: A4V00_01665
AMUR: ADH66_07410
AGAT: RWV98_16160
SGY: Sgly_1518
DMI: Desmer_4162
DEC: DCF50_p1138
HMO: HM1_1146
BPRM: CL3_13500
BPRS: CK3_00760
RHO: RHOM_00840
BMAS: LK422_09255
BLUI: Blut17040_12350
LACY: A4V08_12910
CHYL: CE91St63_29560
CSH: Closa_3476 Closa_3798
CSO: CLS_35520
LXA: OW255_03130
LSIA: VIG27_14805
LUA: D4A81_02550
LGG: QJR73_01610 QJR73_01655
ACEL: acsn021_05310
RTO: RTO_07330
CBOL: CGC65_03665
CASP: NQ535_04235
ECLF: QMP25_25745
STOM: QU660_01640
HHJ: NQ487_27315
LBP: V1224_00830 V1224_10370
AMIJ: EQM06_00985
GFE: Gferi_13890
SRI: SELR_05810
PUF: UFO1_1095
AOC: Aocu_04590(hddA)
EYY: EGYY_07210
RTS: CE91St31_13170(hddA)
MTU: Rv0115(hddA)
MTV: RVBD_0115
MTC: MT0123
MRA: MRA_0121(hddA)
MTF: TBFG_10116
MTB: TBMG_00116
MTK: TBSG_00116
MTZ: TBXG_000116
MTG: MRGA327_00755
MTI: MRGA423_00745
MTE: CCDC5079_0100
MTUR: CFBS_0124(hddA)
MTL: CCDC5180_0100
MTO: MTCTRI2_0118(hddA)
MTD: UDA_0115(hddA)
MTN: ERDMAN_0133(hddA)
MTJ: J112_00635
MTUB: MT7199_0117
MTUC: J113_00815
MTUE: J114_00635
MTUH: I917_00875
MTUL: TBHG_00115
MTUT: HKBT1_0124(hddA)
MTUU: HKBT2_0124(hddA)
MTQ: HKBS1_0124(hddA)
MBO: BQ2027_MB0119(hdda)
MBB: BCG_0149
MBT: JTY_0119
MBM: BCGMEX_0119
MBK: K60_001280
MBX: BCGT_3912
MMIC: RN08_0133
MCE: MCAN_01181(hddA)
MCQ: BN44_10139
MCV: BN43_10134
MCX: BN42_10154
MCZ: BN45_10131
MPA: MAP_0935
MAO: MAP4_2925
MAVI: RC58_14520
MAVU: RE97_14545
MAV: MAV_1118
MAVM: MAA44156_03157(galK_1)
MIT: OCO_09890
MIA: OCU_09910
MID: MIP_01627
MYO: OEM_10070
MCHI: AN480_06105
MIR: OCQ_10000
MMAL: CKJ54_04905
MMAN: MMAN_53260
MSER: MTY59_29240
MMM: W7S_04930
MSHG: MSG_04047
MFJ: MFLOJ_46240
MSTO: MSTO_50140
MSIM: MSIM_36030
MSEO: MSEO_28410
MMAM: K3U93_19695
MHIB: MHIB_05030
SRN: A4G23_00465(hddA)
SLS: SLINC_0247
SFB: CP974_02425
SPEU: CGZ69_25265
SOV: QZH56_04565
STSD: HEP87_37895
DNI: HX89_08010
DAY: FV141_07215
DERM: H7F30_10195
LMOI: VV02_14415
ALX: LVQ62_11820
BEI: GCM100_18490
CFL: Cfla_3600
JTE: ASJ30_08440
JLI: EXU32_05930
JME: EEW87_006825
JAY: H7A72_08590
JCR: O9K63_05260
JAI: V1351_08710
JTR: V3C34_11535
PHW: G7075_07290
PACD: EGX94_01660
ARUB: J5A65_04980
NANO: G5V58_20170
ASEZ: H9L21_09055
ADB: NP095_09275
AWN: NQV15_07320
AMQ: AMETH_0529
ATHM: L1857_05240
ANW: QP939_09600
MCRA: ID554_07380
PFLA: Pflav_030370
PSUU: Psuf_092480
DROS: Drose_17380
DAUR: Daura_25140
ABAM: B1s21122_06220
JCY: M6B22_15975
BSOL: FSW04_03040
PBAJ: LRS13_02260
CWO: Cwoe_5465
PARN: NBH00_10490
TALU: JDY09_01790
AYM: YM304_22980
AQZ: KSP35_05855
IAM: HC251_07750
SYN: slr0862(lmbP)
SYZ: MYO_112400(lmbP)
SYY: SYNGTS_1229(lmbP)
SYT: SYNGTI_1229(lmbP)
SYS: SYNPCCN_1228(lmbP)
SYQ: SYNPCCP_1228(lmbP)
SYJ: D082_22800(lmbP)
SYO: C7I86_06370
SYNH: HTZ78_16440
SYNS: OLK001_26360
PMI: PMT9312_1336
PMH: P9215_14351
PRC: EW14_1456
WNA: KA717_12405
ACAM: HRE53_32790
LEPT: JVX88_02825
KOV: K9N68_31470
GEN: GM3709_2003
GEE: GM3708_2935
CAN: Cyan10605_0572
MAR: MAE_55670
MPK: VL20_390
MIQ: B5D77_10625
MVZ: myaer102_27910
CYU: UCYN_11570
CYT: cce_0966(lmbP)
CWA: CwatDRAFT_2260
CYP: PCC8801_1635
CYH: Cyan8802_1662
NOE: CLI64_01830
CRK: L3I90_05440
CEO: ETSB_0016(lmbP)
CER: RGRSB_1052(lmbP)
CEEC: P3F56_09995
DET: DET0206
DEB: DehaBAV1_0147
DMD: dcmb_209
DMY: X793_00955
DUC: UCH007_02360
RRS: RoseRS_0952 RoseRS_1374 RoseRS_4217
RCA: Rcas_0447 Rcas_3581 Rcas_3592
CAU: Caur_3438 Caur_3750
CHL: Chy400_3700 Chy400_4051
CAG: Cagg_0374 Cagg_0788
HAU: Haur_3668
TTR: Tter_0153 Tter_2647
ATM: ANT_19990
CAP: CLDAP_36340
PBF: CFX0092_A1520
KBS: EPA93_37990
KBB: ccbrp13_38630
THUG: KNN16_04655
CCZ: CCALI_00208 CCALI_02129
CCOT: CCAX7_47070
TRA: Trad_1639
MSV: Mesil_0236
MHD: Marky_1653
AMO: Anamo_1882
TFE: JYK00_02910
MPZ: Marpi_1232
MARN: LN42_06525
FVA: FV113G1_09550
FUL: C4N20_04110
HABY: HLVA_19760(hddA)
MOX: DAMO_0938 DAMO_2477
FSH: Q2T83_17375
MIB: UY43_C0001G0762
NBN: HYY55_04600
GBG: HYW15_01500
MPI: Mpet_1390
MANQ: L1994_11750
TAC: Ta0344 Ta1304
TVO: TVG0491501(TVG0491501) TVG0927911(TVG0927911)
OMR: OXIME_000648 OXIME_001195
PTO: PTO1352
FAC: FACI_IFERC01G0294 FACI_IFERC01G1807
FAI: FAD_0776 FAD_1211
CDIV: CPM_0438 CPM_1015
TAR: TALC_00062
MAX: MMALV_00710
MER: MMINT_13630
MEAR: Mpt1_c11480(mvk2) Mpt1_c11600(galK)
MEUZ: KRP56_00625 KRP56_00640
MARC: AR505_1771
NKR: NKOR_00435
NID: NPIRD3C_0048
NUE: C5F50_00845
NBV: T478_0176
CCAI: NAS2_1392
MARH: Mia14_0639
LOKI: Lokiarch_02870(hddA)
AGW: QT03_C0001G0606
 » show all
Reference
1  [PMID:11279237]
  Authors
Kneidinger B, Graninger M, Puchberger M, Kosma P, Messner P
  Title
Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose.
  Journal
J Biol Chem 276:20935-44 (2001)
DOI:10.1074/jbc.M100378200
  Sequence
[ag:AAK27850]
Reference
2  [PMID:12101286]
  Authors
Valvano MA, Messner P, Kosma P
  Title
Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides.
  Journal
Microbiology 148:1979-89 (2002)
DOI:10.1099/00221287-148-7-1979
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.168
IUBMB Enzyme Nomenclature: 2.7.1.168
ExPASy - ENZYME nomenclature database: 2.7.1.168
BRENDA, the Enzyme Database: 2.7.1.168
LinkDB

DBGET integrated database retrieval system