KEGG ENZYME: 3.6.1.28

ENZYME: 3.6.1.28

Entry

EC 3.6.1.28                 Enzyme

Name

thiamine-triphosphatase

Class

Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides

Sysname

thiamine-triphosphate phosphohydrolase

Reaction(IUBMB)

thiamine triphosphate + H2O = thiamine diphosphate + phosphate [RN:R00618]

Reaction(KEGG)

R00618

Substrate

thiamine triphosphate [CPD:C03028];
H2O [CPD:C00001]

Product

thiamine diphosphate [CPD:C00068];
phosphate [CPD:C00009]

History

EC 3.6.1.28 created 1978

Pathway

ec00730

Thiamine metabolism

ec01100

Metabolic pathways

Orthology

K05307

thiamine-triphosphatase

Genes

HSA:	79178(THTPA)

PPS:	100977058(THTPA)

GGO:	101139989(THTPA)

PON:	100173227(THTPA)

PPYG:

129012832(THTPA)

NLE:	100603625(THTPA)

HMH:	116456227(THTPA)

SSYN:

129489337(THTPA)

MCC:	714403(THTPA)

MCF:	102122817(THTPA)

MTHB:

126958245

MNI:	105499590(THTPA)

CSAB:

103231484(THTPA)

CATY:

105598755(THTPA)

PANU:

101007810(THTPA)

TGE:	112628497(THTPA)

MLEU:

105547200(THTPA)

RRO:	104664867(THTPA)

RBB:	108523593(THTPA)

TFN:	117069953(THTPA)

PTEH:

111554741(THTPA)

CANG:

105503755(THTPA)

CJC:	100401156(THTPA)

SBQ:	101030701(THTPA)

CIMI:

108315358(THTPA)

ANAN:

105727458(THTPA)

CSYR:

103270241(THTPA)

MMUR:

105864724(THTPA)

LCAT:

123620236(THTPA)

PCOQ:

105814439(THTPA)

OGA:	100965363(THTPA)

MMU:	105663(Thtpa)

MCAL:

110309218(Thtpa)

MPAH:

110325225(Thtpa)

RNO:	305889(Thtpa)

MCOC:

116085345(Thtpa)

ANU:	117705901(Thtpa)

ASYL:

127691537(Thtpa)

MUN:	110566649(Thtpa)

CGE:	100764351(Thtpa)

MAUA:

101831628(Thtpa)

PROB:

127230395(Thtpa)

PLEU:

114708766(Thtpa)

MORG:

121434861(Thtpa)

MFOT:

126490881

AAMP:

119800159(Thtpa)

NGI:	103739450(Thtpa)

HGL:	101709464(Thtpa)

CPOC:

100725495(Thtpa)

CCAN:

109696809(Thtpa)

DORD:

105992531(Thtpa)

DSP:	122113405(Thtpa)

PLOP:

125363506(Thtpa)

NCAR:

124976658

MMMA:

107147931(Thtpa)

ITI:	101970702(Thtpa)

OCU:

100346906

OPI:	101535204(THTPA)

TUP:	102485835(THTPA)

GVR:	103585590(THTPA)

CFA:	490614(THTPA)

CLUD:

112657498(THTPA)

VVP:	112926524(THTPA)

VLG:	121493113(THTPA)

NPO:	129499481(THTPA)

AML:	100469428(THTPA)

UMR:	103681052(THTPA)

UAH:	113246055(THTPA)

UAR:	123795769(THTPA)

ELK:

111160872

LLV:

125104932

MPUF:

101672712(THTPA)

MNP:	131999821(THTPA)

MLK:	131836374(THTPA)

NVS:	122894426(THTPA)

ORO:	101384998(THTPA)

EJU:	114217876(THTPA)

ZCA:	113910573(THTPA)

MLX:	118003159(THTPA)

NSU:	110585232(THTPA)

LWW:	102742690(THTPA)

FCA:	101097247(THTPA)

PYU:	121031529(THTPA)

PCOO:

112856160(THTPA)

PBG:	122468907(THTPA)

PVIV:

125167664(THTPA)

LRUF:

124508831

LGF:	123583417(THTPA)

AJU:

106979466

PTG:	102950075(THTPA)

PPAD:

109255014(THTPA)

PUC:

125909673

PLEZ:

122222363(THTPA)

HHV:	120247041(THTPA)

BTA:	282090(THTPA)

BOM:	102275290(THTPA)

BIU:	109564793(THTPA)

BBUB:

102416479(THTPA)

BBIS:

104982014(THTPA)

CHX:	100860962(THTPA)

OAS:	101119565(THTPA)

BTAX:

128053874(THTPA)

CSUM:

138071204(THTPA)

ODA:	120853449(THTPA)

CCAD:

122443189(THTPA)

MREE:

136171664(THTPA)

OVR:	110139475(THTPA)

MBEZ:

129562809(THTPA)

SSC:	396635(THTPA)

CFR:	102515543(THTPA)

CBAI:

105068790(THTPA)

CDK:	105102404(THTPA)

VPC:	102534723(THTPA)

BACU:

103016436(THTPA)

BMUS:

118889639(THTPA)

LVE:	103069060(THTPA)

OOR:	101276979(THTPA)

LALB:

132517655(THTPA)

DLE:	111164125(THTPA)

PCAD:

102974599(THTPA)

PSIU:

116749025(THTPA)

NASI:

112405009(THTPA)

ECB:	100052214(THTPA)

EPZ:	103563006(THTPA)

EAI:	106840632(THTPA)

MYB:	102247331(THTPA)

MYD:	102759266(THTPA)

MMYO:

118679025(THTPA)

MLF:	102441243(THTPA)

MDT:	132240733(THTPA)

MYUM:

139018113(THTPA)

PKL:	118725460(THTPA)

EFUS:

103301503(THTPA)

MNA:	107531712(THTPA)

DRO:	112301268(THTPA)

SHON:

118980924(THTPA)

AJM:	119037222(THTPA)

PDIC:

114493108(THTPA)

PHAS:

123820396(THTPA)

MMF:	118632732(THTPA)

PPAM:

129074146(THTPA)

HAI:	109393637(THTPA)

RFQ:	117023252(THTPA)

PALE:

102878744(THTPA)

PGIG:

120593443(THTPA)

PVP:	105300552(THTPA)

RAY:	107497992(THTPA)

MJV:	108386862(THTPA)

TOD:	119238936(THTPA)

SARA:

101558064(THTPA)

SFUM:

130041172(THTPA)

SETR:

126001215(THTPA)

LAV:	100675702(THTPA)

TMU:

101341633

ETF:	101638964(THTPA)

DNM:	101433271(THTPA)

MDO:	100030627(THTPA)

GAS:	123237982(THTPA)

SHR:	100927206(THTPA)

AFZ:

127551068

PCW:	110194270(THTPA)

TVP:	118828905(THTPA)

PBRV:

138168906(THTPA)

OAA:	100090555(THTPA)

TACU:

119920790(THTPA)

CLV:	102086719(THTPA)

ASN:	102383746(THTPA)

AMJ:	102562068(THTPA)

CCAY:

125622101(THTPA)

DCC:	119842302(THTPA)

CPIC:

101954166(THTPA)

MRV:	120380528(THTPA)

ACS:	100554076(thtpa)

ASAO:

132779302(THTPA)

PVT:	110087822(THTPA)

SUND:

121935168(THTPA)

PBI:	103058184(THTPA)

PMUR:

107293102(THTPA)

CTIG:

120305791(THTPA)

PGUT:

117658206(THTPA)

APRI:

131197327(THTPA)

PTEX:

113448766(THTPA)

NSS:	113422272(THTPA)

VKO:	123018631(THTPA)

PMUA:

114583614(THTPA)

PRAF:

128400608(THTPA)

ZVI:	118094976(THTPA)

HCG:	128330570(THTPA)

GJA:	107117786(THTPA)

STOW:

125445063(THTPA)

EMC:	129338604(THTPA)

XLA:	108714869(thtpa.L) 734744(thtpa.S)

XTR:	100037895(thtpa)

NPR:	108786769(THTPA)

RTEM:

120941158(THTPA)

BBUF:

120991480(THTPA)

BGAR:

122933144(THTPA)

PWL:	138299690(THTPA)

MUO:	115457337(THTPA) 115474239 115474853

GSH:	117361226(THTPA)

DRE:	100048920(thtpa)

SRX:	107735920 107758807

SANH:

107657808 107693802

SGH:	107580794 107581151

CCAR:

109049754 122145009

CAUA:

113042304(thtpa)

CGIB:

128013152

PTET:

122329529(thtpa)

LROH:

127155413(thtpa)

OMC:	131533678(thtpa)

PPRM:

120475915(thtpa)

RKG:	130087681(thtpa)

MAMB:

125258397(thtpa)

CIDE:

127506388

CERY:

137014154(thtpa)

MASI:

127434330

TROS:

130547138(thtpa)

TDW:	130413373(thtpa)

MANU:

129425692(thtpa)

PDAB:

135785494(thtpa)

IPU:

108256428

IFU:	128599819(thtpa)

PHYP:

113541134(thtpa)

SMEO:

124375396(thtpa)

TFD:	113660537(thtpa)

TVC:	132840136(thtpa)

CGAR:

128514254(thtpa)

NGRA:

132867192(thtpa)

TRN:	134301180(thtpa)

AMEX:

103032820(thtpa)

CMAO:

118798649(thtpa)

EEE:	113586085(thtpa)

CHAR:

122130370(thtpa)

SPIL:

134065673(thtpa)

TRU:	101073828(thtpa)

TFS:	130513495(thtpa)

TNG:	GSTEN00009631G001

LCO:	109136786(thtpa)

NCC:	104941948(thtpa)

TBEN:

117484108(thtpa)

CGOB:

115025511(thtpa)

PGEO:

117465735(thtpa)

GACU:

117543654(thtpa)

EMAC:

134883813(thtpa)

ELY:	117264567(thtpa)

EFO:	125881476(thtpa)

PLEP:

121960386(thtpa)

SLUC:

116046297(thtpa)

ECRA:

117938189(thtpa)

ESP:	116672215(thtpa)

PFLV:

114549537(thtpa)

GAT:	120811686(thtpa)

PPUG:

119198367(thtpa)

AFB:	129110962(thtpa)

CLUM:

117749597(thtpa)

PSWI:

130206080(thtpa)

CANA:

137788889(thtpa)

CVE:	137871609(thtpa)

MSAM:

119907600(thtpa)

SCHU:

122867033(thtpa)

CUD:	121527015(thtpa)

SPUL:

138595629(thtpa)

LMIX:

132994344(thtpa)

ALAT:

119008601(thtpa)

ASTR:

137614236(thtpa)

MZE:	101465435(thtpa)

ONL:	100705726(thtpa)

OAU:	116312686(thtpa)

OLA:	101157256(thtpa)

OML:	112151313(thtpa)

CSAI:

133423219(thtpa)

XMA:	102238398(thtpa)

XCO:	114136552(thtpa)

XHE:	116711565(thtpa)

PRET:

103482317(thtpa)

PFOR:

103135322(thtpa)

PLAI:

106963437(thtpa)

PMEI:

106904901(thtpa)

GAF:	122824038(thtpa)

PPRL:

129364651(thtpa)

CVG:	107095243(thtpa)

CTUL:

119776939(thtpa)

GMU:	124858206(thtpa)

NFU:	107382696(thtpa)

KMR:	108245424(thtpa)

ALIM:

106529762(thtpa)

NWH:	119426335(thtpa)

AOCE:

111579353(thtpa)

EJA:	138199383(thtpa)

BFRE:

138620591(thtpa)

MCEP:

124995403(thtpa)

CSEM:

103376930(thtpa)

POV:	109629488(thtpa)

SSEN:

122777282(thtpa)

SSOE:

131456711(thtpa)

HHIP:

117754227(thtpa)

HSP:	118098486(thtpa)

PPLT:

128426041(thtpa)

SMAU:

118290871(thtpa)

LCF:

108898229

SDU:	111239291(thtpa)

SLAL:

111648220(thtpa)

XGL:	120789735(thtpa)

HCQ:	109527880(thtpa)

SSCV:

125985756(thtpa)

PEE:	133396264(thtpa)

PTAO:

133470028(thtpa)

BPEC:

110166312(thtpa)

MALB:

109953009(thtpa)

BSPL:

114854634(thtpa)

SJO:	128382263(thtpa)

SSCO:

134002298(thtpa)

GMH:	115537359(thtpa)

SASA:

100194700(thtpa)

STRU:

115195614(thtpa)

OTW:	112227818(thtpa)

OMY:	110489772(thtpa)

OGO:	124039658(thtpa)

ONE:	115130234(thtpa)

OKI:	109899353(thtpa)

OKE:	118371552(thtpa)

OMM:	135517341(thtpa)

OCLA:

139367058

SALP:

111953958(thtpa)

SNH:	120051054(thtpa)

CCLU:

121570439(thtpa)

ELS:	105019498(thtpa)

SFM:	108927747(thtpa)

PKI:	111840716(thtpa)

AANG:

118224936(thtpa)

AROT:

135252767(thtpa)

CCOG:

133126867(thtpa)

LOC:	107075960(thtpa)

PSPA:

121305166(thtpa)

PSEX:

120525285(thtpa)

LCM:	102354355(THTPA)

LERI:

129716218(thtpa)

PMRN:

116957952(THTPA)

LRJ:	133359723(THTPA)

BFO:

118418704

BBEL:

109479368

LPIC:

129254491

APLC:

110979990

ARUN:

117289177

AAMU:

139934958

AFIL:

140146247

SKO:

100376190

PFLL:

139147175

BCOO:

119072986

LSM:

121117421

DSV:

119437519

RSAN:

119399502

RMP:

119179694

CSCU:

111618297

CVS:

136978768

LPOL:

106478228

PMEO:

129596006

HRO:	HELRODRAFT_79038

LGI:	LOTGIDRAFT_67883

PCAN:

112577409

BGT:	106060532 106072411

CANU:

128189028

CVN:	111135418 111136628

OSN:

115221044

LAK:

106159317

LLON:

135495425

NVE:

5506847

EPA:

110248810

ATEN:

116297414

PDAM:

113665647

SPIS:

111342471

DGT:

114517735

MPP:	MICPUCDRAFT_50547

CME:	CYME_CMI051C

CCP:	CHC_T00004517001

PAN:	PODANSg426 PODANSg4750

PBEL:

QC761_703040

PPSD:

QC762_703040

PPSP:

QC763_703040

PPSA:

QC764_703040

TTT:	THITE_2010984

TRE:	TRIREDRAFT_122499

TRR:	M419DRAFT_82308

TATV:

25784078(TrAtP1_009018)

TASP:

36614702(TrAFT101_002454)

AFV:	AFLA_004988

ALUC:

AKAW2_50141A AKAW2_50206S AKAW2_50421S

ABE:

ARB_03139

TVE:

TRV_07044

PNO:	SNOG_07908

BZE:	COCCADRAFT_112097

ADAC:

96089809(ACET3X_009487)

FFU:	CLAFUR5_04686

RIE:	OCT59_002439

MBR:	MONBRDRAFT_30051

PTI:	PHATRDRAFT_37234

FCY:	FRACYDRAFT_239507

TPS:	THAPSDRAFT_5797

EHX:	EMIHUDRAFT_453444 EMIHUDRAFT_458212

BGW:	VE98_C0001G0180

» show all

Reference

1 [PMID:4335862]

Authors

Hashitani Y, Cooper JR.

Title

The partial purification of thiamine triphosphatase from rat brain.

Journal

J Biol Chem 247:2117-9 (1972)

Other DBs

ExplorEnz - The Enzyme Database:

3.6.1.28

IUBMB Enzyme Nomenclature:

3.6.1.28

ExPASy - ENZYME nomenclature database:

3.6.1.28

BRENDA, the Enzyme Database:

3.6.1.28

CAS:

9068-47-7

LinkDB

DBGET integrated database retrieval system