Entry
Name
protein arginine phosphatase;
YwlE
Class
Hydrolases;
Acting on phosphorus-nitrogen bonds;
Acting on phosphorus-nitrogen bonds (only sub-subclass identified to date)
BRITE hierarchy
Sysname
[protein]-Nomega-phospho-L-arginine phosphohydrolase
Reaction(IUBMB)
a [protein]-Nomega-phospho-L-arginine + H2O = a [protein]-L-arginine + phosphate [RN:
R11095 ]
Reaction(KEGG)
Substrate
[protein]-Nomega-phospho-L-arginine [CPD:
C21101 ];
H2O [CPD:
C00001 ]
Product
Comment
The enzyme, characterized from Gram-positive bacteria, hydrolyses the phosphoramidate (P-N) bond of Nomega-phospho-L-arginine residues in proteins and peptides that were phosphorylated by EC
2.7.14.1 , protein arginine kinase.
History
EC 3.9.1.2 created 2014
Orthology
K20201 protein arginine phosphatase
Genes
LRI : NCTC12151_02280(ywlE_2)
OBG : Verru16b_01976(ywlE)
LCRE : Pla8534_19490(ywlE_1)
AAGG : ETAA8_35200(ywlE_2)
NTI : DNFV4_02976 DNFV4_03636
BAZ : BAMTA208_18705(ywlE)
BFD : NCTC4823_00445(ywlE)
BLEN : NCTC4824_03884(ywlE)
ECTO : MUG87_11670 MUG87_18895
TEI : QS257_19180 QS257_19185
SUQ : HMPREF0772_11076(ptpB)
SDP : NCTC12225_00780(ptpB)
SPIC : SAMEA4384060_0920(ptpB)
SSH : NCTC13712_02056(ptpB)
SSIM : SAMEA4384339_1950(ptpB)
SSTE : SAMEA4384403_0639(ptpB)
LGZ : NCTC10812_02534(ptpB)
PCEL : HUB94_02035 HUB94_27410
CCOH : SAMEA4530647_0163(ywlE)
ACEL : acsn021_42880(ywlE)
ACHT : bsdcttw_03070(ywlE)
PIV : NCTC13079_00316(ywlE)
VRM : 44547418_01164(ywlE)
VDN : NCTC11831_00798(ywlE)
MANA : MAMMFC1_02184(ywlE)
DFO : Dform_00499 Dform_01840
LOKI : Lokiarch_32280(ywlE_2) Lokiarch_41390(ywlE_3) Lokiarch_41400(yfkJ)
» show all
Taxonomy
Reference
Authors
Fuhrmann J, Mierzwa B, Trentini DB, Spiess S, Lehner A, Charpentier E, Clausen T
Title
Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria.
Journal
Sequence
Reference
Authors
Trentini DB, Fuhrmann J, Mechtler K, Clausen T
Title
Chasing Phosphoarginine Proteins: Development of a Selective Enrichment Method Using a Phosphatase Trap.
Journal
Sequence
Reference
Authors
Elsholz AK, Turgay K, Michalik S, Hessling B, Gronau K, Oertel D, Mader U, Bernhardt J, Becher D, Hecker M, Gerth U
Title
Global impact of protein arginine phosphorylation on the physiology of Bacillus subtilis.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.9.1.2
ExPASy - ENZYME nomenclature database: 3.9.1.2
BRENDA, the Enzyme Database: 3.9.1.2
LinkDB
All DBs