Entry |
|
Name |
trans-L-3-hydroxyproline dehydratase;
trans-L-3-hydroxyproline hydro-lyase
|
Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
|
Sysname |
trans-3-hydroxy-L-proline hydro-lyase (1-pyrroline-2-carboxylate-forming)
|
Reaction(IUBMB) |
trans-3-hydroxy-L-proline = 1-pyrroline 2-carboxylate + H2O [RN: R04374]
|
Reaction(KEGG) |
|
Substrate |
trans-3-hydroxy-L-proline [CPD: C05147]
|
Product |
|
Comment |
Highly specific.
|
History |
EC 4.2.1.77 created 1984
|
Pathway |
ec00330 | Arginine and proline metabolism |
|
Orthology |
K18384 | trans-L-3-hydroxyproline dehydratase |
K22548 | trans-L-3-hydroxyproline dehydratase |
|
Genes |
TOD: | 119239143(L3HYPDH) 119242889 119242891 |
XLA: | 108698829(l3hypdh.L) |
MSAM: | 119908610 119919384 |
ARUT: | 117405268 117421952 |
BFO: | 118406711 118406712 118406713 118407066 118407067 118419782 |
BBEL: | 109467419 109467423 |
CIN: | 100178125 100178684 113474013 |
SCLV: | 120327094 120327095 120327099 120327100 120331895 |
LPIC: | 129253852 129260219 129260490 129262393 |
ARUN: | 117292080 117292097 |
AAMU: | 139935712 139935721 |
AFIL: | 140153449 140170021 |
SKO: | 100374014(l3hypdh) 100375070 100375215 100376940 |
PFLL: | 139148407 139149592 |
LGI: | LOTGIDRAFT_118524 LOTGIDRAFT_118892 |
PVUL: | 126821804 126830603 130010457 |
GAE: | 121366440 121371867 121390587 |
CANU: | 128175281 128176576 128179101 |
OED: | 125650802 125652335 125652432 |
MYI: | 110457033 110457034 110457035 110457044 |
PMAX: | 117322638 117323495 117323496 117323497 |
AIRR: | 138318113 138318114 |
MCAF: | 127737123 127738825 127738826 |
MMER: | 123536541 123536542 123545553 |
RPHI: | 132719170 132730780 |
MAEA: | 128207639 128209043 128210954 |
NVE: | 5495736 5501579 5507229 |
ADF: | 107329603 107343685 107343686 |
AMIL: | 114976260 114976269 |
MFOO: | 137985993 137986010 |
DGT: | 114533622 114533660 114533661 |
NHE: | NECHADRAFT_29955 NECHADRAFT_48195 NECHADRAFT_83096 NECHADRAFT_85483 NECHADRAFT_86269 NECHADRAFT_97182 |
FFC: | NCS54_00971900 NCS54_01110300 NCS54_01223000 NCS54_01296800 |
FKR: | NCS57_00021800 NCS57_00494300 NCS57_01100800 NCS57_01210500 |
TATV: | 25778035(TrAtP1_002537) |
MAW: | 19252185(J3458_001621) |
MBRN: | 26237938(G6M90_00g020520) |
PLJ: | 28883761(PLICBS_000303) |
CFJ: | CFIO01_04717 CFIO01_08980 |
CDET: | 87942693(CDEST_06190) |
PFY: | PFICI_09227 PFICI_13991 |
PSCO: | LY89DRAFT_595446 LY89DRAFT_688136 |
ANG: | An05g02210 An08g04750 |
ALUC: | AKAW2_30571A AKAW2_81362A |
CCAC: | CcaHIS019_0312460(CcaverHIS019_0312460) |
MRR: | Moror_4294 Moror_5541 |
HAFN: | KF947_04535 KF947_05060 |
HOL: | HORIV_48420 HORIV_50770 |
HNP: | SR894_14020 SR894_14735 |
SPSE: | SULPSESMR1_03590 SULPSESMR1_03888 SULPSESMR1_04291 |
PPAN: | ESD82_09105 ESD82_09165 |
» show all
|
Reference |
1 |
Authors |
Ramaswamy SG. |
Title |
Conversion of 3-hydroxyproline to proline in the rat requires reduced pyridine-nucleotides. |
Journal |
Fed Proc 42:2232 (1983) |
Reference |
|
Authors |
Visser WF, Verhoeven-Duif NM, de Koning TJ |
Title |
Identification of a human trans-3-hydroxy-L-proline dehydratase, the first characterized member of a novel family of proline racemase-like enzymes. |
Journal |
|
Sequence |
|
Other DBs |
ExplorEnz - The Enzyme Database: | 4.2.1.77 |
ExPASy - ENZYME nomenclature database: | 4.2.1.77 |
|
LinkDB |
|