| Entry |
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| Name |
(-)-beta-caryophyllene synthase;
beta-caryophyllene synthase;
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (caryophyllene-forming)
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| Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
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| Sysname |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(-)-beta-caryophyllene-forming]
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| Reaction(IUBMB) |
(2E,6E)-farnesyl diphosphate = (-)-beta-caryophyllene + diphosphate [RN: R08541]
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| Reaction(KEGG) |
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| Substrate |
(2E,6E)-farnesyl diphosphate [CPD: C00448]
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| Product |
(-)-beta-caryophyllene [CPD: C09629];
diphosphate [CPD: C00013]
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| Comment |
Widely distributed in higher plants, cf. EC 4.2.3.89 (+)-beta-caryophyllene synthase.
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| History |
EC 4.2.3.57 created 2011, modified 2011
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| Pathway |
| ec00909 | Sesquiterpenoid and triterpenoid biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K14184 | alpha-humulene/beta-caryophyllene synthase |
| K15808 | beta-caryophyllene synthase |
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| Genes |
| EUS: | EUTSA_v10012105mg EUTSA_v10012129mg |
| BRP: | 103849526 103849591 103874257 |
| RSZ: | 108831150 108831714 108832465 108840558 |
| THJ: | 104818160 104818164 104818498 |
| TWL: | 119985452 119988733 120010736 |
| MUS: | 103992270 108951961 135585998 135616208 135617577 135617578 135623694 |
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| Reference |
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| Authors |
Cai Y, Jia JW, Crock J, Lin ZX, Chen XY, Croteau R |
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| Title |
A cDNA clone for beta-caryophyllene synthase from Artemisia annua. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.2.3.57 |
| ExPASy - ENZYME nomenclature database: | 4.2.3.57 |
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| LinkDB |
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