| Entry |
|
|---|
| Name |
Nalbuphine hydrochloride (USAN);
Nubain (TN) |
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| Product |
|
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| Generic |
NALBUPHINE HCI (HF Acquisition Co LLC), NALBUPHINE HCI (HF Acquisition Co LLC), NALBUPHINE HYDROCHLORIDE (Henry Schein), NALBUPHINE HYDROCHLORIDE (Henry Schein), NALBUPHINE HYDROCHLORIDE (Henry Schein), NALBUPHINE HYDROCHLORIDE (Hospira), NALBUPHINE HYDROCHLORIDE (Hospira), NALBUPHINE HYDROCHLORIDE (Medical Purchasing Solutions), NALBUPHINE HYDROCHLORIDE (Medical Purchasing Solutions), NALBUPHINE HYDROCHLORIDE (Medical Purchasing Solutions), NALBUPHINE HYDROCHLORIDE (Somerset Therapeutics), NALBUPHINE HYDROCHLORIDE (Somerset Therapeutics) |
|---|
| Formula |
C21H27NO4. HCl
|
|---|
| Exact mass |
393.1707
|
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| Mol weight |
393.90
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
|
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| Remark |
| Product (DG00822): | D00843<US> |
|
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| Efficacy |
Analgesic, Narcotic antagonist, Opioid receptor agonist/antagonist |
|---|
| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AF Morphinan derivatives
N02AF02 Nalbuphine
D00843 Nalbuphine hydrochloride (USAN) <US>
USP drug classification [BR:br08302]
Analgesics
Opioid Analgesics, Short-acting
Nalbuphine
D00843 Nalbuphine hydrochloride (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00822 Nalbuphine
D00843 Nalbuphine hydrochloride
Analgesic
DG01984 Opioid analgesics
DG00822 Nalbuphine
D00843 Nalbuphine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D00843 Nalbuphine hydrochloride (USAN) <US>
OPRK1
D00843 Nalbuphine hydrochloride (USAN) <US>
OPRD1
D00843 Nalbuphine hydrochloride (USAN) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00822 Nalbuphine
Analgesic
DG01984 Opioid analgesics
DG00822 Nalbuphine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 27
1 X Cl 14.6606 -12.8905
2 C1z C 6.9594 -14.2694
3 C8y C 6.9594 -12.9454
4 C1z C 8.1440 -14.9661
5 C1y C 5.8445 -14.8965
6 C1x C 8.1440 -13.6423
7 C8y C 5.8445 -12.3183
8 C8y C 8.1440 -12.3183
9 C1y C 9.2589 -14.2694
10 C1x C 8.1440 -16.2204
11 O2x O 4.5206 -13.5725
12 C1y C 5.8445 -16.2204
13 C1x C 10.3737 -13.6423
14 C8y C 5.8445 -10.9944
15 C1x C 9.2589 -13.0151
16 C8x C 8.1440 -10.9944
17 N1y N 10.3737 -14.9661
18 C1x C 6.9594 -16.9172
19 O1a O 4.7297 -16.9172
20 C8x C 7.0291 -10.3673
21 O1a O 4.7297 -10.3673
22 O1a O 9.3982 -15.8720
23 C1b C 11.7726 -14.9661
24 C1y C 12.4755 -16.1834
25 C1x C 12.1154 -17.5269
26 C1x C 13.4590 -17.8870
27 C1x C 13.8190 -16.5434
BOND 31
1 2 3 1
2 2 4 1
3 2 5 1
4 2 6 1 #Up
5 3 7 2
6 3 8 1
7 4 9 1
8 4 10 1
9 5 11 1 #Down
10 5 12 1
11 6 13 1
12 7 14 1
13 8 15 1
14 8 16 2
15 9 17 1 #Up
16 10 18 1
17 12 19 1 #Down
18 14 20 2
19 14 21 1
20 7 11 1
21 9 15 1
22 12 18 1
23 13 17 1
24 16 20 1
25 4 22 1 #Up
26 17 23 1
27 23 24 1
28 24 25 1
29 25 26 1
30 26 27 1
31 24 27 1
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