Entry |
|
Name |
Naproxen sodium (USP); Anaprox (TN) |
Product |
|
Generic |
NAPROXEN (Granules India), NAPROXEN (Northwind Pharmaceuticals), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN SODIUM (A-S Medication Solutions), NAPROXEN SODIUM (Alvogen), NAPROXEN SODIUM (Amneal Pharmaceuticals of New York LLC), NAPROXEN SODIUM (Asclemed USA), NAPROXEN SODIUM (Aurobindo Pharma Limited), NAPROXEN SODIUM (AvPAK), NAPROXEN SODIUM (Bryant Ranch Prepack), NAPROXEN SODIUM (Bryant Ranch Prepack), NAPROXEN SODIUM (Bryant Ranch Prepack), NAPROXEN SODIUM (Bryant Ranch Prepack), NAPROXEN SODIUM (Bryant Ranch Prepack), NAPROXEN SODIUM (Bryant Ranch Prepack), NAPROXEN SODIUM (Bryant Ranch Prepack), NAPROXEN SODIUM (Direct Rx), NAPROXEN SODIUM (Dr. Reddy's Laboratories), NAPROXEN SODIUM (NuCare Pharmaceuticals), NAPROXEN SODIUM (PD-Rx Pharmaceuticals), NAPROXEN SODIUM (PD-Rx Pharmaceuticals), NAPROXEN SODIUM (Preferred Pharmaceuticals), NAPROXEN SODIUM (Proficient Rx LP), NAPROXEN SODIUM (Proficient Rx LP), NAPROXEN SODIUM (Proficient Rx LP), NAPROXEN SODIUM (Quality Care Products), NAPROXEN SODIUM (REMEDYREPACK), NAPROXEN SODIUM (REMEDYREPACK), NAPROXEN SODIUM (SA3), NAPROXEN SODIUM (ST. MARY'S MEDICAL PARK PHARMACY), NAPROXEN SODIUM (ScieGen Pharmaceuticals), NAPROXEN SODIUM (Teva Pharmaceuticals), NAPROXEN SODIUM (Upsher-Smith Laboratories) |
Formula |
C14H13O3. Na
|
Exact mass |
252.0762
|
Mol weight |
252.24
|
Structure |

|
Simcomp |
|
Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
|
Remark |
Product (DG00455): | D00118<JP/US> D00970<US> |
Product (mixture): | D11577<US> |
|
Efficacy |
Analgesic, Anti-inflammatory, Antipyretic, COX inhibitor |
Disease |
Rheumatoid arthritis [DS: H00630] Ankylosing spondylitis [DS: H01674] Polyarticular juvenile idiopathic arthritis [DS: H01672] Acute gout [DS: H01532] |
Comment |
Propionic acid derivative
|
Target |
|
Pathway |
|
Interaction |
|
Structure map |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G02 OTHER GYNECOLOGICALS
G02C OTHER GYNECOLOGICALS
G02CC Antiinflammatory products for vaginal administration
G02CC02 Naproxen
D00970 Naproxen sodium (USP) <US>
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AE Propionic acid derivatives
M01AE02 Naproxen
D00970 Naproxen sodium (USP) <US>
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA12 Naproxen
D00970 Naproxen sodium (USP) <US>
USP drug classification [BR:br08302]
Analgesics
Nonsteroidal Anti-inflammatory Drugs
Naproxen
D00970 Naproxen sodium (USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
DG00455 Naproxen
D00970 Naproxen sodium
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D00970 Naproxen sodium
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D00970 Naproxen sodium (USP) <US>
PTGS2 (COX2)
D00970 Naproxen sodium (USP) <US>
Rx-to-OTC switch list in the USA [br08315.html]
D00970
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
DG00455 Naproxen
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Other DBs |
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LinkDB |
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KCF data |
ATOM 18
1 C8y C 23.5997 -20.0988
2 C8y C 23.5997 -21.4993
3 C8x C 24.7901 -19.3985
4 C8x C 22.3393 -19.3985
5 C8x C 22.3393 -22.1995
6 C8x C 24.7901 -22.1995
7 C8y C 25.9806 -20.0988
8 C8x C 21.1489 -20.0988
9 C8y C 21.1489 -21.4993
10 C8x C 25.9806 -21.4993
11 C1c C 27.2410 -19.3985
12 O2a O 19.9584 -22.1995
13 C6a C 28.4314 -20.0988
14 C1a C 27.2410 -17.9980
15 C1a C 18.6980 -21.4993
16 O6a O 28.4314 -21.4993
17 O6a O 29.6219 -19.3985 #-
18 Z Na 31.5125 -19.3985 #+
BOND 18
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 5 9 2
9 6 10 2
10 7 11 1
11 9 12 1
12 11 13 1
13 11 14 1 #Down
14 12 15 1
15 13 16 2
16 13 17 1
17 7 10 1
18 8 9 1
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