| Entry |
|
|---|
| Name |
Butropium bromide (JP18/INN);
Coliopan (TN) |
|---|
| Formula |
C28H38NO4. Br
|
|---|
| Exact mass |
531.1984
|
|---|
| Mol weight |
532.51
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
DG01975 Agents for peptic ulcer
|
|---|
| Efficacy |
Antispasmodic, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Tropane derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
D01491 Butropium bromide
Gastrointestinal agent
DG01975 Agents for peptic ulcer
D01491 Butropium bromide
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D01491 Butropium bromide (JP18/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01491 Butropium bromide
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 34
1 C1x C 14.3738 -18.8808
2 C1x C 14.7019 -17.7091
3 C1y C 15.5455 -18.5996
4 C1y C 15.8736 -17.4279
5 N2y N 14.6082 -16.1156 #+
6 C1x C 17.4202 -18.5996
7 C1x C 17.1390 -17.4279
8 C1y C 18.4513 -19.1620
9 O7a O 19.5293 -20.0525
10 C7a C 20.7479 -20.0525
11 C1c C 21.3572 -18.9745
12 O6a O 21.3572 -21.1773
13 C8y C 22.5758 -18.9745
14 C1b C 20.7479 -17.9434
15 O1a O 21.3572 -16.8655
16 C8x C 23.2820 -20.1982
17 C8x C 24.6820 -20.1985
18 C8x C 25.3822 -18.9862
19 C8x C 24.6761 -17.7625
20 C8x C 23.2761 -17.7622
21 C1a C 13.8591 -14.9314
22 C1b C 13.3789 -16.7283
23 C8y C 12.2062 -15.9518
24 C8x C 12.2062 -14.5518
25 C8x C 10.9938 -13.8518
26 C8y C 9.7813 -14.5518
27 C8x C 9.7813 -15.9518
28 C8x C 10.9938 -16.6518
29 O2a O 8.5864 -13.8619
30 C1b C 7.3926 -14.5513
31 C1b C 6.2045 -13.8654
32 C1b C 5.0136 -14.5531
33 C1a C 3.8240 -13.8663
34 X Br 18.4100 -15.1200 #-
BOND 36
1 1 2 1
2 1 3 1
3 2 4 1
4 3 5 1
5 3 6 1
6 4 7 1
7 6 8 1
8 8 9 1 #Down
9 9 10 1
10 10 11 1
11 10 12 2
12 11 13 1
13 11 14 1 #Down
14 14 15 1
15 4 5 1
16 7 8 1
17 13 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 13 20 1
23 5 21 1
24 5 22 1
25 22 23 1
26 23 24 2
27 24 25 1
28 25 26 2
29 26 27 1
30 27 28 2
31 23 28 1
32 26 29 1
33 29 30 1
34 30 31 1
35 31 32 1
36 32 33 1
|
|---|
