Entry |
|
Name |
Pranoprofen (JP18/INN); Elicapric (TN) |
Formula |
C15H13NO3
|
Exact mass |
255.0895
|
Mol weight |
255.27
|
Structure |

|
Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
|
Remark |
Therapeutic category: | 1319 |
|
Efficacy |
Analgesic, Anti-inflammatory, Antipyretic, COX inhibitor |
Comment |
Propionic acid derivative
|
Target |
|
Pathway |
|
Interaction |
|
Structure map |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BC Antiinflammatory agents, non-steroids
S01BC09 Pranoprofen
D01578 Pranoprofen (JP18/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D01578 Pranoprofen (JP18/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for ophthalmologic use
62 General eye drops
D01578 Pranoprofen (JP18/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Pranoprofen
D01578 Pranoprofen (JP18/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
D01578 Pranoprofen
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D01578 Pranoprofen
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D01578 Pranoprofen (JP18/INN) <JP>
PTGS2 (COX2)
D01578 Pranoprofen (JP18/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01578 Pranoprofen
Rx-to-OTC switch list in Japan [br08314.html]
D01578
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 19
1 C8x C 23.5900 -26.2500
2 C8x C 23.5900 -24.8500
3 C8x C 24.7800 -24.1500
4 N5x N 24.7800 -26.9500
5 C8y C 25.9700 -26.2500
6 C8y C 25.9700 -24.8500
7 C1x C 27.2300 -24.1500
8 O2x O 27.2300 -26.9500
9 C8y C 28.4200 -26.2500
10 C8y C 28.4200 -24.8500
11 C8x C 29.6100 -24.1500
12 C8y C 30.8700 -24.7800
13 C8x C 30.8700 -26.1800
14 C8x C 29.6800 -26.8800
15 C1c C 32.0600 -24.0800
16 C1a C 32.0600 -22.6800
17 C6a C 33.2500 -24.7800
18 O6a O 34.4400 -24.0800
19 O6a O 33.2500 -26.1800
BOND 21
1 5 4 2
2 4 1 1
3 1 2 2
4 2 3 1
5 3 6 2
6 9 10 2
7 10 11 1
8 11 12 2
9 12 13 1
10 13 14 2
11 14 9 1
12 5 6 1
13 12 15 1
14 6 7 1
15 15 16 1
16 7 10 1
17 15 17 1
18 9 8 1
19 17 18 1
20 8 5 1
21 17 19 2
|