| Entry |
|
|---|
| Name |
Oxprenolol hydrochloride (JP18/USP);
Okuspurecol (TN) |
|---|
| Formula |
C15H23NO3. HCl
|
|---|
| Exact mass |
301.1445
|
|---|
| Mol weight |
301.81
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiarrhythmic, Vasodilator, beta-Adrenergic receptor antagonist |
|---|
| Comment |
Propranolol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07A BETA BLOCKING AGENTS
C07AA Beta blocking agents, non-selective
C07AA02 Oxprenolol
D01806 Oxprenolol hydrochloride (JP18/USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG00304 Oxprenolol
D01806 Oxprenolol hydrochloride
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00304 Oxprenolol
D01806 Oxprenolol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D01806 Oxprenolol hydrochloride (JP18/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01806 Oxprenolol hydrochloride
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG00304 Oxprenolol
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00304 Oxprenolol
|
|---|
| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 20
1 X Cl 18.2097 -28.2160
2 O2a O 11.6200 -24.2200
3 C1b C 12.8100 -23.5200
4 C1c C 14.0700 -24.2200
5 C1b C 15.2600 -23.5200
6 N1b N 16.4500 -24.2200
7 C1c C 17.7100 -23.5200
8 C1a C 18.9000 -24.2200
9 O1a O 14.0700 -25.6200
10 C1a C 17.7100 -22.1200
11 C8y C 11.6200 -25.6200
12 C8y C 10.4076 -26.3200
13 C8x C 10.4076 -27.7200
14 C8x C 11.6200 -28.4200
15 C8x C 12.8324 -27.7200
16 C8x C 12.8324 -26.3200
17 O2a O 9.2121 -25.6296
18 C1b C 8.0247 -26.3151
19 C2b C 6.8335 -25.6271
20 C2a C 5.6440 -26.3138
BOND 19
1 4 5 1
2 5 6 1
3 6 7 1
4 7 8 1
5 4 9 1
6 7 10 1
7 2 3 1
8 3 4 1
9 2 11 1
10 11 12 2
11 12 13 1
12 13 14 2
13 14 15 1
14 15 16 2
15 11 16 1
16 12 17 1
17 17 18 1
18 18 19 1
19 19 20 2
|
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