| Entry |
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| Name |
Bromperidol decanoate (USAN) |
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| Formula |
C31H41BrFNO3
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| Exact mass |
573.2254
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| Mol weight |
574.56
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
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| Remark |
| Product (DG00890): | D01101<JP> |
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| Efficacy |
Antipsychotic, Dopamine D2 receptor antagonist |
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| Comment |
Butyrophenone derivative
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
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| Interaction |
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| Structure map |
| map07031 | Antipsychotics - butyrophenones |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AD Butyrophenone derivatives
N05AD06 Bromperidol
D02626 Bromperidol decanoate (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00890 Bromperidol
D02626 Bromperidol decanoate
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00890 Bromperidol
D02626 Bromperidol decanoate
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00890 Bromperidol
D02626 Bromperidol decanoate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D02626 Bromperidol decanoate (USAN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D02626
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00890 Bromperidol
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00890 Bromperidol
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00890 Bromperidol
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 37
1 C1b C 21.9180 -16.5412
2 C1b C 23.0946 -15.8490
3 C1b C 24.2712 -16.5412
4 N1y N 25.5170 -15.8490
5 C1x C 25.5170 -14.4647
6 C1x C 26.6937 -16.5412
7 C1x C 26.6937 -13.7726
8 C1x C 27.8704 -15.8490
9 C1z C 27.8704 -14.4647
10 C8y C 29.0469 -13.7726
11 C8x C 29.0469 -12.3883
12 C8x C 30.2236 -14.4647
13 C8x C 30.2236 -11.6962
14 C8x C 31.4002 -13.7726
15 C8y C 31.4002 -12.3883
16 X Br 32.6461 -11.6962
17 C5a C 20.6721 -15.8490
18 C8y C 19.4955 -16.5412
19 O5a O 20.6721 -14.3955
20 C8x C 19.4955 -17.9254
21 C8x C 18.2496 -18.6176
22 C8y C 17.0729 -17.9254
23 C8x C 17.0729 -16.5412
24 C8x C 18.2496 -15.8490
25 X F 15.7579 -18.6176
26 O7a O 29.0469 -15.1569
27 C7a C 29.0469 -16.5412
28 O6a O 27.8482 -17.2332
29 C1b C 30.2457 -17.2332
30 C1b C 31.5833 -16.5412
31 C1a C 33.1287 -17.2332
32 C1b C 30.2457 -17.2332
33 C1b C 31.5833 -16.5412
34 C1b C 30.2457 -17.2332
35 C1b C 31.5833 -16.5412
36 C1b C 30.2457 -17.2332
37 C1b C 31.5833 -16.5412
BOND 39
1 9 10 1
2 10 11 1
3 10 12 2
4 11 13 2
5 12 14 1
6 13 15 1
7 15 16 1
8 8 9 1
9 14 15 2
10 1 17 1
11 1 2 1
12 17 18 1
13 2 3 1
14 17 19 2
15 3 4 1
16 4 5 1
17 4 6 1
18 5 7 1
19 6 8 1
20 18 20 1
21 20 21 2
22 21 22 1
23 22 23 2
24 23 24 1
25 24 18 2
26 7 9 1
27 22 25 1
28 9 26 1
29 26 27 1
30 27 28 2
31 27 29 1
32 29 30 1
33 30 32 1
34 32 33 1
35 33 34 1
36 34 35 1
37 35 36 1
38 36 37 1
39 37 31 1
BRACKET 1 29.8900 -17.9900 29.8900 -16.2400
1 31.6400 -16.2400 31.6400 -17.9900
1 4
ORIGINAL 1 29 30
REPEAT 1 32 33 34 35 36 37
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