| Entry |
|
|---|
| Name |
Butorphanol (USAN/INN) |
|---|
| Formula |
C21H29NO2
|
|---|
| Exact mass |
327.2198
|
|---|
| Mol weight |
327.46
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
|
|---|
| Remark |
| Product (DG00821): | D00837<US> |
|
|---|
| Efficacy |
Analgesic, Antitussive, Opioid receptor agonist/antagonist |
|---|
| Comment |
Opioid alkaloid, morphinan
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AF Morphinan derivatives
N02AF01 Butorphanol
D03197 Butorphanol (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00821 Butorphanol
D03197 Butorphanol
Analgesic
DG01984 Opioid analgesics
DG00821 Butorphanol
D03197 Butorphanol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D03197 Butorphanol (USAN/INN)
OPRK1
D03197 Butorphanol (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00821 Butorphanol
Analgesic
DG01984 Opioid analgesics
DG00821 Butorphanol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 24
1 C1z C 31.7771 -18.9290
2 C1z C 32.9418 -19.6104
3 C8y C 31.7771 -17.5721
4 C1x C 33.0640 -18.0555
5 C1x C 30.5949 -19.5929
6 C1y C 34.1299 -18.8766
7 C1x C 32.9418 -20.9616
8 O1a O 34.1182 -20.3676
9 C8y C 32.9477 -16.8966
10 C8x C 30.5890 -16.8966
11 C1x C 35.3121 -18.0496
12 C1x C 30.5832 -20.9499
13 N1y N 35.3121 -19.5346
14 C1x C 34.1940 -17.5838
15 C1x C 31.7595 -21.6255
16 C8x C 32.9477 -15.5395
17 C8y C 30.5890 -15.5395
18 C1b C 36.6632 -19.5346
19 C8x C 31.7828 -14.8582
20 O1a O 29.4184 -14.8582
21 C1y C 37.3445 -20.7111
22 C1x C 36.9951 -22.0215
23 C1x C 38.6666 -21.0546
24 C1x C 38.3113 -22.3650
BOND 28
1 1 2 1
2 1 3 1
3 1 4 1 #Up
4 1 5 1
5 2 6 1
6 2 7 1
7 2 8 1 #Up
8 3 9 2
9 3 10 1
10 4 11 1
11 5 12 1
12 6 13 1 #Up
13 6 14 1
14 7 15 1
15 9 16 1
16 10 17 2
17 13 18 1
18 16 19 2
19 17 20 1
20 18 21 1
21 21 22 1
22 21 23 1
23 22 24 1
24 9 14 1
25 13 11 1 #Up
26 12 15 1
27 17 19 1
28 23 24 1
|
|---|
