| Entry |
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| Name |
Flufenamate aluminum (JAN);
Flufenamic acid aluminum;
Opyrin (TN) |
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| Formula |
(C14H9F3NO2)3. Al
|
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| Exact mass |
867.1572
|
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| Mol weight |
867.64
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| Structure |
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| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
|
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| Remark |
| Therapeutic category: | 1141 |
| Product (DG00757): | D01823<JP> D03254<JP> |
|
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| Efficacy |
Analgesic, Anti-inflammatory, Antipyretic, COX inhibitor |
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| Comment |
Aniline derivative, Fenamic acid derivative
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AG Fenamates
M01AG03 Flufenamic acid
D03254 Flufenamate aluminum (JAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
114 Antipyretics and analgesics, anti-inflammatory agents
1141 Anilines
D03254 Flufenamate aluminum (JAN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
DG00757 Flufenamic acid
D03254 Flufenamate aluminum
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D03254 Flufenamate aluminum
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D03254 Flufenamate aluminum (JAN) <JP>
PTGS2 (COX2)
D03254 Flufenamate aluminum (JAN) <JP>
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
DG00757 Flufenamic acid
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 61
1 C8x C 19.6700 -19.4600
2 C8y C 19.6700 -18.0600
3 C8y C 18.4576 -17.3600
4 C8x C 17.2451 -18.0600
5 C8x C 17.2451 -19.4600
6 C8x C 18.4576 -20.1600
7 N1b N 20.8824 -17.3600
8 C8y C 22.0779 -18.0504
9 C8x C 22.0779 -19.4597
10 C8x C 23.2904 -20.1597
11 C8x C 24.5028 -19.4597
12 C8y C 24.5028 -18.0503
13 C8x C 23.2903 -17.3504
14 C6a C 18.4576 -15.9602
15 O6a O 19.6868 -15.2504 #-
16 O6a O 17.2620 -15.2698
17 C1d C 25.7089 -17.3540
18 X F 26.9214 -16.6540
19 X F 26.4089 -18.5664
20 X F 25.0089 -16.1415
21 Z Al 32.5500 -17.8500 #3+
22 C8x C 19.6700 -19.4600
23 C8y C 19.6700 -18.0600
24 C8y C 18.4576 -17.3600
25 C8x C 17.2451 -18.0600
26 C8x C 17.2451 -19.4600
27 C8x C 18.4576 -20.1600
28 C6a C 18.4576 -15.9602
29 O6a O 19.6868 -15.2504 #-
30 O6a O 17.2620 -15.2698
31 N1b N 20.8824 -17.3600
32 C8y C 22.0779 -18.0504
33 C8x C 22.0779 -19.4597
34 C8x C 23.2904 -20.1597
35 C8x C 24.5028 -19.4597
36 C8y C 24.5028 -18.0503
37 C8x C 23.2903 -17.3504
38 C1d C 25.7089 -17.3540
39 X F 26.9214 -16.6540
40 X F 26.4089 -18.5664
41 X F 25.0089 -16.1415
42 C8x C 19.6700 -19.4600
43 C8y C 19.6700 -18.0600
44 C8y C 18.4576 -17.3600
45 C8x C 17.2451 -18.0600
46 C8x C 17.2451 -19.4600
47 C8x C 18.4576 -20.1600
48 C6a C 18.4576 -15.9602
49 O6a O 19.6868 -15.2504 #-
50 O6a O 17.2620 -15.2698
51 N1b N 20.8824 -17.3600
52 C8y C 22.0779 -18.0504
53 C8x C 22.0779 -19.4597
54 C8x C 23.2904 -20.1597
55 C8x C 24.5028 -19.4597
56 C8y C 24.5028 -18.0503
57 C8x C 23.2903 -17.3504
58 C1d C 25.7089 -17.3540
59 X F 26.9214 -16.6540
60 X F 26.4089 -18.5664
61 X F 25.0089 -16.1415
BOND 63
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 7 8 1
9 8 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 8 13 2
15 3 14 1
16 14 15 1
17 14 16 2
18 12 17 1
19 17 18 1
20 17 19 1
21 17 20 1
22 22 23 2
23 23 24 1
24 24 25 2
25 25 26 1
26 26 27 2
27 22 27 1
28 23 31 1
29 31 32 1
30 32 33 1
31 33 34 2
32 34 35 1
33 35 36 2
34 36 37 1
35 32 37 2
36 24 28 1
37 28 29 1
38 28 30 2
39 36 38 1
40 38 39 1
41 38 40 1
42 38 41 1
43 42 43 2
44 43 44 1
45 44 45 2
46 45 46 1
47 46 47 2
48 42 47 1
49 43 51 1
50 51 52 1
51 52 53 1
52 53 54 2
53 54 55 1
54 55 56 2
55 56 57 1
56 52 57 2
57 44 48 1
58 48 49 1
59 48 50 2
60 56 58 1
61 58 59 1
62 58 60 1
63 58 61 1
BRACKET 1 15.8200 -21.0000 15.8200 -14.0000
1 28.2800 -14.0000 28.2800 -21.0000
1 3
ORIGINAL 1 1 2 3 4 5 6 14 15 16 7 8 9 10 11 12 13
1 17 18 19 20
REPEAT 1 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
1 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53
1 54 55 56 57 58 59 60 61
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