 | | DRUG: Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride | |
| Entry |
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| Name |
Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride;
Sekicode (TN) |
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| Component |
Dihydrocodeine phosphate [DR: D01481], Ephedrine hydrochloride [DR: D01386], Ammonium chloride [DR: D01139]
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| Class |
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| Remark |
| Therapeutic category: | 2249 |
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| Efficacy |
Antitussive, Expectorant |
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| Comment |
Dihydrocodeine phosphate is metabolized by UGT2B7, UGT2B4 with some contribution from CYP3A4 and CYP2D6.
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| Metabolism |
Enzyme: UGT2B7 [HSA: 7364], UGT2B4 [HSA: 7363]; CYP3A4 [HSA: 1576], CYP2D6 [HSA: 1565]
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| Interaction |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
22 Respiratory organ agents
224 Antitussives and expectorants
2249 Others
D04338 Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride
Drug groups [BR:br08330]
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
D04338 Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D04338 Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride
DG02924 UGT substrate
DG03189 UGT2B4 substrate
D04338 Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride
DG03190 UGT2B7 substrate
D04338 Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride
Unclassified
DG03282 Ephedrine-containing preparation
D04338 Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D04338
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| Other DBs |
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| LinkDB |
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