| Entry |
|
|---|
| Name |
Fendiline (INN) |
|---|
| Formula |
C23H25N
|
|---|
| Exact mass |
315.1987
|
|---|
| Mol weight |
315.45
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01575 Calcium channel blocker
DG01496 Calcium channel L type blocker
DG01653 Antiarrhythmics
DG01807 Phenylalkylamine derivative
|
|---|
| Remark |
|
|---|
| Efficacy |
Vasodilator, Calcium channel blocker |
|---|
| Target |
|
|---|
| Pathway |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C08 CALCIUM CHANNEL BLOCKERS
C08E NON-SELECTIVE CALCIUM CHANNEL BLOCKERS
C08EA Phenylalkylamine derivatives
C08EA01 Fendiline
D07185 Fendiline (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01575 Calcium channel blocker
DG01496 Calcium channel L type blocker
DG00332 Fendiline
D07185 Fendiline
DG01653 Antiarrhythmics
DG01807 Phenylalkylamine derivative
DG00332 Fendiline
D07185 Fendiline
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Calcium channels
CACNA1-L
D07185 Fendiline (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01575 Calcium channel blocker
DG01496 Calcium channel L type blocker
DG00332 Fendiline
DG01653 Antiarrhythmics
DG01807 Phenylalkylamine derivative
DG00332 Fendiline
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 24
1 C8x C 9.6600 -11.7600
2 C8x C 9.6600 -13.1600
3 C8x C 10.8724 -13.8600
4 C8x C 12.0849 -13.1600
5 C8y C 12.0849 -11.7600
6 C8x C 10.8724 -11.0600
7 C1c C 13.3160 -11.0490
8 C8y C 14.5212 -11.7447
9 C8x C 14.5216 -13.1596
10 C8x C 15.7342 -13.8593
11 C8x C 16.9465 -13.1589
12 C8x C 16.9460 -11.7439
13 C8x C 15.7334 -11.0443
14 C1b C 13.3157 -9.6601
15 C1b C 14.5162 -8.9666
16 N1b N 15.7062 -9.6535
17 C1c C 16.8960 -8.9662
18 C8y C 18.0863 -9.6532
19 C1a C 16.8959 -7.5602
20 C8x C 18.0866 -11.0597
21 C8x C 19.2992 -11.7595
22 C8x C 20.5115 -11.0592
23 C8x C 20.5112 -9.6527
24 C8x C 19.2986 -8.9530
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 8 13 1
15 7 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 17 19 1
21 18 20 2
22 20 21 1
23 21 22 2
24 22 23 1
25 23 24 2
26 18 24 1
|
|---|
