| Entry |
|
|---|
| Name |
Benzatropine (INN);
Benztropine |
|---|
| Formula |
C21H25NO
|
|---|
| Exact mass |
307.1936
|
|---|
| Mol weight |
307.43
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
|
|---|
| Remark |
| Product (DG00859): | D00778<US> |
|
|---|
| Efficacy |
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Tropane derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04A ANTICHOLINERGIC AGENTS
N04AC Ethers of tropine or tropine derivatives
N04AC01 Benzatropine
D07511 Benzatropine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00859 Benzatropine
D07511 Benzatropine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D07511 Benzatropine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00859 Benzatropine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 23
1 C1x C 14.4215 -15.7645
2 C1x C 14.7705 -14.6480
3 C1y C 15.5381 -15.4854
4 C1y C 15.8172 -14.3689
5 N1y N 14.6309 -13.1826
6 C1x C 17.2827 -15.4854
7 C1x C 17.0035 -14.3689
8 C1y C 18.2596 -15.9739
9 O2a O 19.2366 -16.8113
10 C1a C 13.9331 -12.0660
11 C1c C 20.5625 -16.8113
12 C8y C 21.2603 -17.9976
13 C8y C 21.2603 -15.6948
14 C8x C 22.6560 -15.6948
15 C8x C 23.2840 -14.5084
16 C8x C 22.6560 -13.3221
17 C8x C 21.2603 -13.3221
18 C8x C 20.5625 -14.5084
19 C8x C 20.6323 -19.1839
20 C8x C 21.3301 -20.3702
21 C8x C 22.6560 -20.3702
22 C8x C 23.2840 -19.1839
23 C8x C 22.6560 -17.9976
BOND 26
1 1 2 1
2 1 3 1
3 2 4 1
4 3 5 1
5 3 6 1
6 4 7 1
7 6 8 1
8 8 9 1 #Down
9 4 5 1
10 7 8 1
11 5 10 1
12 9 11 1
13 11 12 1
14 11 13 1
15 13 14 2
16 14 15 1
17 15 16 2
18 16 17 1
19 17 18 2
20 13 18 1
21 12 19 2
22 19 20 1
23 20 21 2
24 21 22 1
25 22 23 2
26 12 23 1
|
|---|
