| Entry |
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| Name |
Ofloxacin hydrochloride;
Tarivid (TN) |
|---|
| Formula |
C18H20FN3O4. xHCl
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| Structure |
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| Simcomp |
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| Class |
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
|---|
| Remark |
| Product (DG00616): | D00453<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Nucleic acid biosynthesis inhibitor |
|---|
| Target |
|
|---|
| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
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| Interaction |
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| Structure map |
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| Other map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01M QUINOLONE ANTIBACTERIALS
J01MA Fluoroquinolones
J01MA01 Ofloxacin
D08291 Ofloxacin hydrochloride
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AE Fluoroquinolones
S01AE01 Ofloxacin
D08291 Ofloxacin hydrochloride
S02 OTOLOGICALS
S02A ANTIINFECTIVES
S02AA Antiinfectives
S02AA16 Ofloxacin
D08291 Ofloxacin hydrochloride
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00616 Ofloxacin
D08291 Ofloxacin hydrochloride
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00616 Ofloxacin
D08291 Ofloxacin hydrochloride
Antimicrobials [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
D08291 Ofloxacin hydrochloride
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08291
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00616 Ofloxacin
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00616 Ofloxacin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
DG00616 Ofloxacin
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 27
1 C8y C 25.4100 -18.2700
2 C8y C 24.2200 -18.9700
3 C8y C 25.4100 -16.8700
4 N4y N 26.6000 -18.9700
5 C8y C 22.9600 -18.2700
6 O2x O 24.2200 -20.3700
7 C8y C 26.6000 -16.1700
8 C8x C 24.2200 -16.1700
9 C8x C 27.8600 -18.2700
10 C1y C 26.6000 -20.3700
11 N1y N 21.7700 -18.9700
12 C8y C 22.9600 -16.8700
13 C1x C 25.4100 -21.0700
14 C8y C 27.8600 -16.8700
15 O5x O 26.6000 -14.7700
16 C1a C 27.8600 -21.0700
17 C1x C 20.5800 -18.2700
18 C1x C 21.7700 -20.3700
19 X F 21.7700 -16.1700
20 C6a C 29.0500 -16.1700
21 C1x C 19.3200 -18.9700
22 C1x C 20.5800 -21.0700
23 O6a O 29.0500 -14.7700
24 O6a O 30.2400 -16.8700
25 N1y N 19.3200 -20.3700
26 C1a C 18.1300 -21.0700
27 X Cl 33.5300 -20.3700
BOND 29
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 1
9 4 10 1
10 5 11 1
11 5 12 1
12 6 13 1
13 7 14 1
14 7 15 2
15 10 16 1
16 11 17 1
17 11 18 1
18 12 19 1
19 14 20 1
20 17 21 1
21 18 22 1
22 20 23 2
23 20 24 1
24 21 25 1
25 25 26 1
26 8 12 2
27 9 14 2
28 10 13 1
29 22 25 1
BRACKET 1 31.9900 -21.1400 31.9900 -19.3900
1 34.5800 -19.3900 34.5800 -21.1400
1 x
ORIGINAL 1 27
REPEAT 1
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