| Entry |
|
|---|
| Name |
Tropatepine hydrochloride;
Lepticur (TN) |
|---|
| Formula |
C22H23NS. HCl
|
|---|
| Exact mass |
369.1318
|
|---|
| Mol weight |
369.95
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Atropine [CPD: C01479] derivative; Tricyclic compound
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04A ANTICHOLINERGIC AGENTS
N04AA Tertiary amines
N04AA12 Tropatepine
D08653 Tropatepine hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00858 Tropatepine
D08653 Tropatepine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D08653 Tropatepine hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00858 Tropatepine
|
|---|
| Other DBs |
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|---|
| LinkDB |
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|---|
| KCF data |
ATOM 25
1 X Cl 27.4851 -17.6694
2 C1x C 17.2176 -14.7680
3 C1x C 17.4976 -13.6482
4 C1y C 18.3374 -14.3481
5 C1y C 18.6874 -13.2282
6 N1y N 17.5676 -11.8984
7 C1x C 20.0872 -14.3481
8 C1x C 19.8772 -13.2282
9 C2y C 21.0671 -14.9080
10 C1a C 16.8676 -10.7086
11 C2y C 21.0671 -16.3778
12 C8y C 22.2569 -16.9377
13 C8y C 22.5369 -18.1976
14 S2x S 21.6970 -19.2474
15 C8y C 19.8773 -16.9377
16 C1x C 20.4372 -19.2474
17 C8y C 19.5973 -18.1976
18 C8x C 18.9674 -16.0279
19 C8x C 17.7075 -16.3778
20 C8x C 17.3576 -17.7076
21 C8x C 18.3375 -18.5475
22 C8x C 23.7967 -18.6175
23 C8x C 24.7766 -17.7776
24 C8x C 24.4966 -16.4478
25 C8x C 23.2368 -16.0978
BOND 28
1 2 3 1
2 2 4 1
3 3 5 1
4 4 6 1
5 4 7 1
6 5 8 1
7 7 9 1
8 5 6 1
9 8 9 1
10 6 10 1
11 13 14 1
12 11 15 1
13 14 16 1
14 12 13 1
15 15 17 1
16 11 12 1
17 16 17 1
18 15 18 2
19 18 19 1
20 19 20 2
21 20 21 1
22 17 21 2
23 13 22 2
24 22 23 1
25 23 24 2
26 24 25 1
27 12 25 2
28 9 11 2
|
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