KEGG ORTHOLOGY: K05141

ORTHOLOGY: K05141

Entry

K05141                      KO

Symbol

TNFRSF1B, TNFR2, CD120b

Name

tumor necrosis factor receptor superfamily member 1B

Pathway

map04060

Cytokine-cytokine receptor interaction

map04061

Viral protein interaction with cytokine and cytokine receptor

map04668

TNF signaling pathway

map04920

Adipocytokine signaling pathway

map05014

Amyotrophic lateral sclerosis

map05022

Pathways of neurodegeneration - multiple diseases

map05170

Human immunodeficiency virus 1 infection

Disease

H00084

Graft-versus-host disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    K05141  TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05141  TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05141  TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
09150 Organismal Systems
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K05141  TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05141  TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    K05141  TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
   05022 Pathways of neurodegeneration - multiple diseases
    K05141  TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05141  TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
   04090 CD molecules
    K05141  TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
Cytokine receptors [BR:ko04050]
Tumor necrosis factor receptors
  TNF receptor superfamily
   K05141  TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
CD molecules [BR:ko04090]
Proteins
  K05141  CD120b, TNFRSF1B; tumor necrosis factor receptor superfamily, member 1B

Other DBs

GO:

0005031

Genes

HSA:	7133(TNFRSF1B)

PTR:	457968(TNFRSF1B)

PPS:	100972621(TNFRSF1B)

GGO:	101136411(TNFRSF1B)

PON:	100447138(TNFRSF1B)

PPYG:

129007588(TNFRSF1B)

NLE:	100579764(TNFRSF1B)

HMH:	116812940(TNFRSF1B)

SSYN:

129472061(TNFRSF1B)

MCC:	715454(TNFRSF1B)

MCF:	102144224(TNFRSF1B)

MTHB:

126953149

MNI:	105473177(TNFRSF1B)

CSAB:

103225587(TNFRSF1B)

CATY:

105580845(TNFRSF1B)

PANU:

101024834(TNFRSF1B)

TGE:	112608993(TNFRSF1B)

MLEU:

105551364(TNFRSF1B)

RRO:	104668929(TNFRSF1B)

RBB:	108539384(TNFRSF1B)

TFN:	117093300(TNFRSF1B)

PTEH:

111526326(TNFRSF1B)

CANG:

105526541(TNFRSF1B)

CJC:	100394148(TNFRSF1B)

SBQ:	101040812(TNFRSF1B)

CIMI:

108286567(TNFRSF1B)

ANAN:

105731801(TNFRSF1B)

CSYR:

103276043(TNFRSF1B)

MMUR:

105882708(TNFRSF1B)

LCAT:

123634459(TNFRSF1B)

PCOQ:

105824987(TNFRSF1B)

OGA:	100963314(TNFRSF1B)

MMU:	21938(Tnfrsf1b)

MCAL:

110292554(Tnfrsf1b)

MPAH:

110323744(Tnfrsf1b)

RNO:	156767(Tnfrsf1b)

MCOC:

116096996(Tnfrsf1b)

ANU:	117709653(Tnfrsf1b)

ASYL:

127681597(Tnfrsf1b)

MUN:	110555750(Tnfrsf1b)

CGE:	100774542(Tnfrsf1b)

MAUA:

101840577(Tnfrsf1b)

PROB:

127213303(Tnfrsf1b)

PLEU:

114685523(Tnfrsf1b)

MORG:

121441827 121448888

MFOT:

126508214

AAMP:

119817843(Tnfrsf1b)

NGI:	103747487(Tnfrsf1b)

HGL:	101712824(Tnfrsf1b)

CPOC:

100723273(Tnfrsf1b)

CCAN:

109683967(Tnfrsf1b)

DORD:

105997476(Tnfrsf1b)

DSP:	122121491(Tnfrsf1b)

PLOP:

125354587(Tnfrsf1b)

NCAR:

124983857

MMMA:

107155486(Tnfrsf1b)

ITI:	101959099(Tnfrsf1b)

OCU:

100349872

OPI:	101523232(TNFRSF1B)

TUP:	102471631(TNFRSF1B)

GVR:	103605089(TNFRSF1B)

CFA:	487437(TNFRSF1B)

CLUD:

112678127

VVP:	112929758(TNFRSF1B)

VLG:	121497550(TNFRSF1B)

NPO:	129513994(TNFRSF1B)

AML:	100473387(TNFRSF1B)

UMR:	103666853(TNFRSF1B)

UAH:	113270492(TNFRSF1B)

UAR:	123779623(TNFRSF1B)

ELK:

111154868

LLV:

125098107

MPUF:

101689344(TNFRSF1B)

MNP:	132001283(TNFRSF1B)

MLK:	131809080(TNFRSF1B)

NVS:	122899468(TNFRSF1B)

ORO:	101372518(TNFRSF1B)

EJU:	114213409(TNFRSF1B)

ZCA:	113934417(TNFRSF1B)

MLX:	118019994(TNFRSF1B)

NSU:	110574678(TNFRSF1B)

LWW:	102730528(TNFRSF1B)

FCA:	101080392(TNFRSF1B)

PYU:	121021339(TNFRSF1B)

PCOO:

112861663(TNFRSF1B)

PBG:	122479941(TNFRSF1B)

PVIV:

125172709(TNFRSF1B)

LRUF:

124514755

LGF:	123597196(TNFRSF1B)

AJU:

106988169

PTG:	102971882(TNFRSF1B)

PPAD:

109274128(TNFRSF1B)

PUC:

125913105

PLEZ:

122226276(TNFRSF1B)

HHV:	120224910(TNFRSF1B)

BTA:	338033(TNFRSF1B)

BOM:	102265200(TNFRSF1B)

BIU:	109570565(TNFRSF1B)

BBIS:

104995825(TNFRSF1B)

CHX:	102191447(TNFRSF1B)

OAS:	100240715(TNFRSF1B)

BTAX:

128061416(TNFRSF1B)

CSUM:

138090369(TNFRSF1B)

ODA:	120880236(TNFRSF1B)

CCAD:

122452071(TNFRSF1B)

MREE:

136168364(TNFRSF1B)

OVR:	110139530(TNFRSF1B)

MBEZ:

129551552(TNFRSF1B)

SSC:	100037306(TNFRSF1B)

CFR:	102507931(TNFRSF1B)

CBAI:

105071154(TNFRSF1B)

CDK:	105107099(TNFRSF1B)

VPC:	102534204(TNFRSF1B)

BACU:

103018633(TNFRSF1B)

BMUS:

118905750(TNFRSF1B)

LVE:	103081795(TNFRSF1B)

OOR:	101289721(TNFRSF1B)

LALB:

132515221(TNFRSF1B)

DLE:	111187038(TNFRSF1B)

PCAD:

102983071(TNFRSF1B)

PSIU:

116756594(TNFRSF1B)

NASI:

112402681(TNFRSF1B)

ECB:	100055840(TNFRSF1B)

EPZ:	103552189(TNFRSF1B)

EAI:	106836661(TNFRSF1B)

MYB:	102258042(TNFRSF1B)

MYD:	102762080(TNFRSF1B)

MMYO:

118676259(TNFRSF1B)

MLF:	102429153(TNFRSF1B)

MDT:	132231670(TNFRSF1B)

MYUM:

139002884(TNFRSF1B)

PKL:	118731983(TNFRSF1B)

EFUS:

103295336(TNFRSF1B)

MNA:	107531534(TNFRSF1B)

DRO:	112299573(TNFRSF1B)

SHON:

118986335(TNFRSF1B)

AJM:	119064091(TNFRSF1B)

PDIC:

114497620(TNFRSF1B)

PHAS:

123832252(TNFRSF1B)

MMF:	118626273(TNFRSF1B)

PPAM:

129075646(TNFRSF1B)

HAI:	109381233(TNFRSF1B)

RFQ:	117027578(TNFRSF1B)

PALE:

102880090(TNFRSF1B)

PGIG:

120585805(TNFRSF1B)

PVP:	105294424(TNFRSF1B)

RAY:	107513133(TNFRSF1B)

TOD:	119235263(TNFRSF1B)

TMU:

101357884

ETF:	101662341(TNFRSF1B)

DNM:	101440631(TNFRSF1B)

MDO:	103097127(TNFRSF1B)

SHR:	100914374(TNFRSF1B)

AFZ:

127555856

PCW:	110198958(TNFRSF1B)

TVP:

118839926

PBRV:

138154624(TNFRSF1B)

OAA:	103166118(TNFRSF1B)

TACU:

119928379(TNFRSF1B)

GGA:	395083(TNFRSF1B)

PCOC:

116242550(TNFRSF1B)

MGP:

100544932

TPAI:

128085130(TNFRSF1B)

LMUT:

125703495(TNFRSF1B)

NMEL:

110408602(TNFRSF1B)

APLA:

101791359

ACYG:

106040213(TNFRSF1B)

CATA:

118253327(TNFRSF1B)

AFUL:

116497610(TNFRSF1B)

TGU:	100222629(TNFRSF1B)

LSR:

110479725

SCAN:

103820948(TNFRSF1B)

PMOA:

120496733

OTC:	121344102(TNFRSF1B)

PRUF:

121358476(TNFRSF1B)

ATRC:

139600667

GFR:	102038421(TNFRSF1B)

FAB:	101820094(TNFRSF1B)

OMA:	130261770(TNFRSF1B)

PHI:	102110597(TNFRSF1B)

PMAJ:

107213655(TNFRSF1B)

CCAE:

CCW:

CBRC:

ACOE:

ETL:

ZAB:	102063739(TNFRSF1B)

ZLE:	135456597(TNFRSF1B)

ACHL:

103811159(TNFRSF1B)

SVG:	106856439(TNFRSF1B)

MMEA:

130583471(TNFRSF1B)

SATI:

136370745(TNFRSF1B)

CCIC:

134052777

FPG:	101913467(TNFRSF1B)

FCH:

102058714

CCRI:

104154481(TNFRSF1B)

NNT:	104399789(TNFRSF1B)

SHAB:

115617460

ACUN:

113487968(TNFRSF1B)

TALA:

104364952(TNFRSF1B)

ACHC:

115343357(TNFRSF1B)

HALD:

104310833(TNFRSF1B)

HLE:	104838014(TNFRSF1B)

AGEN:

126043138

HHAR:

128144327(TNFRSF1B)

GCL:

127024857

LDI:	104339745(TNFRSF1B)

MNB:	103770516(TNFRSF1B)

DPUB:

104305913(TNFRSF1B)

PPUS:

135190633(TNFRSF1B)

BRHI:

104491918

EGZ:	104133145(TNFRSF1B)

NNI:	104009084(TNFRSF1B)

PCRI:

104028581

PCAO:

104039482(TNFRSF1B)

PADL:

103918051(TNFRSF1B)

AFOR:

103907560

FGA:	104069135(TNFRSF1B)

CLV:

102093466

MUI:	104540137(TNFRSF1B)

PLET:

104614458(TNFRSF1B)

EHS:	104510595(TNFRSF1B)

CMAC:

104481508(TNFRSF1B)

CUCA:

104060604

TEO:	104369758(TNFRSF1B)

BREG:

104638986(TNFRSF1B)

OHA:	104332995(TNFRSF1B)

ACAR:

104517561(TNFRSF1B)

CPEA:

104395526(TNFRSF1B)

CVF:	104282952(TNFRSF1B)

RTD:	128918477(TNFRSF1B)

AAM:	106482459(TNFRSF1B)

AROW:

112970131(TNFRSF1B)

NPD:	112959641(TNFRSF1B)

TGT:	104570932(TNFRSF1B)

DNE:	112980584(TNFRSF1B)

SCAM:

104141852(TNFRSF1B)

ASN:	102376932(TNFRSF1B)

AMJ:	102576216(TNFRSF1B)

CPOO:

109314397

GGN:	109293557(TNFRSF1B)

PSS:	102450568(TNFRSF1B)

CMY:

102933534

CCAY:

125624521(TNFRSF1B)

DCC:

119845199

CPIC:

101942730(TNFRSF1B)

TST:	117869556(TNFRSF1B)

CABI:

116821901

ACS:	103282768(tnfrsf1b)

PVT:

110070508

SUND:

121936976

PBI:

103053956

PGUT:

117656621(TNFRSF1B)

APRI:

131187179(TNFRSF1B)

PTEX:

113450792

NSS:

113427330

VKO:	123034692(TNFRSF1B)

PMUA:

114602604(TNFRSF1B)

PRAF:

128419636

ZVI:

118087121

HCG:	128338672(TNFRSF1B)

GJA:

107124770

STOW:

125445808(TNFRSF1B)

EMC:	129345017(TNFRSF1B)

PWL:

138301129

DRE:	100037357(tnfrsf1b)

SRX:

107756653

SANH:

107654410 107702005

SGH:	107582473 107592893

CCAR:

109063729

CAUA:

113055454 113055536 113110880

CGIB:

127968513 128022060

PTET:

122353620(tnfrsf1b)

LROH:

127173303(tnfrsf1b)

OMC:	131548919(tnfrsf1b)

PPRM:

120480789(tnfrsf1b)

RKG:	130088510(tnfrsf1b)

MAMB:

125256232(tnfrsf1b)

CIDE:

127522307

CERY:

137021395(tnfrsf1b)

MASI:

127426604 127427887

TROS:

130570962(tnfrsf1b)

TDW:	130410528(tnfrsf1b)

MANU:

129427822(tnfrsf1b)

PDAB:

135740669(tnfrsf1b)

IPU:	108255052(tnfrsf1b)

IFU:	128625216(tnfrsf1b)

PHYP:

113537964

SMEO:

124402473(tnfrsf1b)

TFD:	113657188(tnfrsf1b)

TVC:	132838042(tnfrsf1b)

CGAR:

128511390(tnfrsf1b)

NGRA:

132874582(tnfrsf1b)

TRN:	134302129(tnfrsf1b)

AMEX:

103026920(tnfrsf1b)

CMAO:

118799706(tnfrsf1b)

EEE:

113582016

CHAR:

105909873(tnfrsf1b)

SPIL:

134091743(tnfrsf1b)

TRU:	101078488(tnfrsf14)

TFS:	130523994(tnfrsf1b)

TNG:	GSTEN00027562G001

LCO:

104919357

NCC:

104951270

TBEN:

117489884(tnfrsf1b)

CGOB:

115007687

PGEO:

117447405(tnfrsf1b)

GACU:

117548229(tnfrsf1b)

EMAC:

134882647(tnfrsf1b)

ELY:	117256572(tnfrsf1b)

EFO:	125892231(tnfrsf1b)

PLEP:

121959886(tnfrsf1b)

SLUC:

116051302(tnfrsf1b)

ECRA:

117943144(tnfrsf1b)

ESP:

116688621

PFLV:

114554940

GAT:	120834666(tnfrsf1b)

PPUG:

119194282(tnfrsf1b)

AFB:	129106089(tnfrsf1b)

CLUM:

117730815(tnfrsf1b)

PSWI:

130208341(tnfrsf1b)

CANA:

137796668(tnfrsf1b)

CVE:	137873836(tnfrsf1b)

MSAM:

119885694(tnfrsf1b)

SCHU:

122861624(tnfrsf1b)

CUD:	121507500(tnfrsf1b)

SPUL:

138606080(tnfrsf1b)

LMIX:

132978087(tnfrsf1b)

ALAT:

119021133(tnfrsf1b)

ASTR:

137595708(tnfrsf1b)

MZE:

101468373

ONL:	100690893(tnfrsf1b)

OAU:	116316515(tnfrsf1b)

OLA:

101172894

OML:	112145271(tnfrsf1b)

CSAI:

133449406(tnfrsf1b)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122833898(tnfrsf1b)

PPRL:

129358291(tnfrsf1b)

CVG:

107087524

CTUL:

119772746(tnfrsf1b)

GMU:	124857375(tnfrsf1b)

NFU:

107385264

KMR:	108231575(tnfrsf1b)

ALIM:

106513844

NWH:	119411821(tnfrsf1b)

AOCE:

111588021(tnfrsf1b)

EJA:	138196101(tnfrsf1b)

BFRE:

138616502(tnfrsf1b)

MCEP:

125007048(tnfrsf1b)

CSEM:

103385695

POV:

109638541

SSEN:

122767688(tnfrsf1b)

SSOE:

131460992(tnfrsf1b)

HHIP:

117760994(tnfrsf1b)

HSP:	118104842(tnfrsf1b)

PPLT:

128447734(tnfrsf1b)

SMAU:

118309050(tnfrsf1b)

LCF:	108899907(tnfrsf1b)

SDU:

111223963

SLAL:

111657911

XGL:	120783477(tnfrsf1b)

HCQ:

109529183

SBIA:

133507511(tnfrsf1b)

PEE:	133408373(tnfrsf1b)

PTAO:

133483987(tnfrsf1b)

BPEC:

110166948

MALB:

109959064

BSPL:

114856265(tnfrsf1b)

SJO:	128356015(tnfrsf1b)

SSCO:

133977605(tnfrsf1b)

SASA:

106565709 106565991(TR11B) 106582823

STRU:

115150912 115207515

OTW:	112220637 112254322(tnfrsf1b)

OMY:	110494628 110527838(tnfrsf1b)

OGO:	124003733 124031529(tnfrsf1b)

ONE:	115136748 115143424

OKI:	109890907 109898319

OKE:	118388314 118400043(tnfrsf1b)

OMM:	135542194(tnfrsf1b)

OCLA:

139369902 139413323

SALP:

111969796 111969817

SNH:	120059180 120064944(tnfrsf1b)

CCLU:

121574836 121578433(tnfrsf1b)

ELS:

105017393

SFM:	108918204 108924936

PKI:	111857110 111859073

AANG:

118207706

AROT:

135233928

CCOG:

133139372

LOC:	107075583 107075592

PSPA:

121325425 121329192(tnfrsf1b)

ARUT:

117424459 117425209 117425342 117425550

LCM:	102363849(TNFRSF1B)

RTP:	109921030 125486671

CPLA:

HOC:

LERI:

APLC:

Reference

PMID:2172983

Authors

Kohno T, Brewer MT, Baker SL, Schwartz PE, King MW, Hale KK, Squires CH, Thompson RC, Vannice JL

Title

A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor.

Journal

Proc Natl Acad Sci U S A 87:8331-5 (1990)
DOI:10.1073/pnas.87.21.8331

Sequence

[hsa:7133]

Reference

PMID:14688072

Authors

Lainez B, Fernandez-Real JM, Romero X, Esplugues E, Canete JD, Ricart W, Engel P

Title

Identification and characterization of a novel spliced variant that encodes human soluble tumor necrosis factor receptor 2.

Journal

Int Immunol 16:169-77 (2004)
DOI:10.1093/intimm/dxh014

LinkDB

DBGET integrated database retrieval system