KEGG   ORTHOLOGY: K13574
Entry
K13574                      KO                                     
Symbol
hcxB
Name
hydroxycarboxylate dehydrogenase B [EC:1.1.1.237 1.1.1.-]
Pathway
map00350  Tyrosine metabolism
map00360  Phenylalanine metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R01370  phenyllactate:NAD+ oxidoreductase
R01371  phenyllactate:NADP+ oxidoreductase
R03337  (R)-3-(4-hydroxyphenyl)lactate:NAD+ 2-oxidoreductase
R03339  (R)-3-(4-hydroxyphenyl)lactate:NADP+ 2-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    K13574  hcxB; hydroxycarboxylate dehydrogenase B
   00360 Phenylalanine metabolism
    K13574  hcxB; hydroxycarboxylate dehydrogenase B
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.237  hydroxyphenylpyruvate reductase
     K13574  hcxB; hydroxycarboxylate dehydrogenase B
Other DBs
COG: COG2055
GO: 0047995
Genes
ECO: b0801(hcxB)
ECJ: JW0786(ybiC)
ECD: ECDH10B_0869(ybiC)
EBW: BWG_0654(ybiC)
ECOK: ECMDS42_0651(ybiC)
ECOC: C3026_05055
ECE: Z1022(ybiC)
ECS: ECs_0879(ybiC)
ECF: ECH74115_0950
ETW: ECSP_0898(ybiC)
ELX: CDCO157_0857
EOI: ECO111_0862(ybiC)
EOJ: ECO26_0924(ybiC)
EOH: ECO103_0837(ybiC)
ECOO: ECRM13514_0878(ybiC)
ECOH: ECRM13516_0833(ybiC)
ESL: O3K_17345
ESO: O3O_07945
ESM: O3M_17315
ECK: EC55989_0845(ybiC)
ECG: E2348C_0753(ybiC)
EOK: G2583_1029(ybiC)
ELR: ECO55CA74_04995
ELH: ETEC_0868
ECW: EcE24377A_0869
EUN: UMNK88_841
ECP: ECP_0815
ENA: ECNA114_0734(ybiC)
ECOS: EC958_0914(ybiC)
ECV: APECO1_1289(ybiC)
ECOA: APECO78_07675
ECX: EcHS_A0856
ECM: EcSMS35_0825
ECY: ECSE_0857
ECR: ECIAI1_0839(ybiC)
ECQ: ECED1_0766(ybiC)
EUM: ECUMN_0945(ybiC)
ECT: ECIAI39_0778(ybiC)
EOC: CE10_0822(ybiC)
EBR: ECB_00768(ybiC)
ECOB: C3029_08270
EBL: ECD_00768(ybiC)
EBE: B21_00785(ybiC)
EBD: ECBD_2822
ECI: UTI89_C0804(ybiC)
EIH: ECOK1_0804
ECZ: ECS88_0819(ybiC)
ECC: c0885(ybiC)
ELO: EC042_0891
ELN: NRG857_03580
ESE: ECSF_0727
ECL: EcolC_2842
EKF: KO11_19775(ybiC)
EAB: ECABU_c08430(ybiC)
EDH: EcDH1_2841
EDJ: ECDH1ME8569_0754(ybiC)
ELU: UM146_13640
ELW: ECW_m0857(ybiC)
ELL: WFL_04165(ybiC)
ELC: i14_0850(ybiC)
ELD: i02_0850(ybiC)
ELP: P12B_c0790(ybiC)
ELF: LF82_2638(ybiC)
ECOL: LY180_04220
ECOI: ECOPMV1_00803(ybiC)
ECOJ: P423_03975
EFE: EFER_2307(ybiC)
EAL: EAKF1_ch0669c
EMA: C1192_08315
ESZ: FEM44_18510
ERUY: OSH18_05715
SFL: SF0751(ybiC)
SFX: S0792(ybiC)
SFV: SFV_0784(ybiC)
SFE: SFxv_0817(ybiC)
SFN: SFy_1020
SFS: SFyv_1062
SFT: NCTC1_00758(ybiC)
SSN: SSON_0780(ybiC)
SBO: SBO_0689(ybiC)
SBC: SbBS512_E2551
SDY: SDY_0798(ybiC)
SDZ: Asd1617_01003
SHQ: A0259_07955
SHIG: LXH19_14865(hcxB)
KPN: KPN_02089
KPU: KP1_3177
KPM: KPHS_30690
KPP: A79E_2154
KPH: KPNIH24_13095
KPZ: KPNIH27_14700
KPV: KPNIH29_15355
KPW: KPNIH30_15635
KPY: KPNIH31_14490
KPG: KPNIH32_15530
KPC: KPNIH10_15160
KPQ: KPR0928_15135
KPT: VK055_0373
KPO: KPN2242_13400
KPR: KPR_2631(ybiC)
KPJ: N559_2201
KPI: D364_10710
KPA: KPNJ1_02376
KPS: KPNJ2_02334
KPX: PMK1_04453(ybiC)
KPB: FH42_06540
KPNE: KU54_010985
KPNU: LI86_10940
KPNK: BN49_3194(ybiC)
KVA: Kvar_2185
KPE: KPK_2241
KPK: A593_25410
KVD: KR75_23335
KVQ: SP68_04050
KQU: AVR78_19520
KQV: B8P98_11955
KOX: KOX_18735 KOX_22540
KOE: A225_2618 A225_3382
KOY: J415_15110 J415_18885
KOM: HR38_17100 HR38_20840
KOK: KONIH1_12525 KONIH1_16575
KOC: AB185_19325
EAE: EAE_17445
EAR: CCG30404
KLL: BJF97_16700
KLW: DA718_12245
KAR: LGL98_10470
KGR: JJJ10_12210
KPAS: LUW96_23190
KLC: K7H21_11925
KLM: BWI76_16775
REE: electrica_01980(ybiC_1) electrica_02154(ybiC_2)
KLP: GUC22_11090
ROR: RORB6_04420
RON: TE10_17060
RPLN: B1209_11075
RAO: DSD31_10850
RTG: NCTC13098_02582(ybiC_1) NCTC13098_03134(ybiC_2)
CKO: CKO_02080
CFD: CFNIH1_14120
CBRA: A6J81_08975
CWE: CO701_14780
CYO: CD187_16155
CPOT: FOB25_03655
CFQ: C2U38_08175
CIF: AL515_08610
CIE: AN232_22325
CPAR: CUC49_03815
CITZ: E4Z61_00990
CARS: E1B03_09210
CIX: M4I31_15600
CIB: HF677_015760
CITR: GUC46_15855
CIQ: FD428_13135
CEM: LH23_17850
PGE: LG71_13660
KOR: AWR26_07420
KRD: A3780_16540
KOU: C0557_18060
KCA: AAEY27_06855
SYM: K6K13_11430
AHN: NCTC12129_02563(ybiC)
ASUB: NLZ15_11070
KIN: AB182_12390 AB182_18530
PDZ: HHA33_15075 HHA33_21005
METY: MRY16398_29140(ybiC) MRY16398_42030
IZH: FEM41_12230
MPHG: MPHASIOC01_003540
EBC: C2U52_23280 C2U52_29745
EBU: CUC76_00540
PSTS: E05_07330
SMAR: SM39_1490
SMAC: SMDB11_1291
SMW: SMWW4_v1c20410(ybiC)
SPE: Spro_2010
SRR: SerAS9_1961
SRL: SOD_c18420(ybiC)
SRY: M621_10145
SPLY: Q5A_010085(ybiC)
SRS: SerAS12_1961
SRA: SerAS13_1962
SMAF: D781_1855
SLQ: M495_09840
SRZ: AXX16_3279
SERM: CLM71_09250
SQU: E4343_06090
SFJ: SAMEA4384070_2085(ybiC_2)
SOF: NCTC11214_04882(ybiC)
SSUR: ATE40_006730
SURI: J0X03_13805
SRHZ: FO014_00575
SENP: KHA73_10260
SNEM: NLX84_10280
SGRI: SGBXF1_02037(ybiC)
SSAR: SSARUM_001952
GQU: AWC35_00900 AWC35_03550
SERA: Ser39006_011830
SERQ: CWC46_11825
PROD: PCO85_12655
ECA: ECA1527
PATR: EV46_07725
PATO: GZ59_15650
PCT: PC1_1400 PC1_1845
PCC: PCC21_019060
PCV: BCS7_07065
PWA: Pecwa_1798 Pecwa_2132
PPAR: A8F97_08210 A8F97_09785
PEC: W5S_1712 W5S_2077
PWS: A7983_18130 A7983_22515
PPOA: BJK05_02250 BJK05_04260
PBRA: B5S52_12455
PPUJ: E2566_09885
PARI: I2D83_10070 I2D83_14995
PVZ: OA04_24140 OA04_28810
PPOO: LW347_07580 LW347_09670
PCAC: OI450_10325
PACB: M9782_09525 M9782_11760
PARL: PEC302110_13720 PEC302110_18450
PPEU: DUT67_14345
DDD: Dda3937_02253 Dda3937_02692
DZE: Dd1591_1632
DDC: Dd586_1595
DZC: W909_12045
DSO: A4U42_00945 A4U42_16640
CED: LH89_04530 LH89_21165
DFN: CVE23_08230 CVE23_13820
DDQ: DDI_1237 DDI_2492
DAQ: DAQ1742_02832
DIC: Dpoa569_0001528 Dpoa569_0002405
DLC: O1Q98_04280
DDA: Dd703_1300 Dd703_1601
BGJ: AWC36_08580 AWC36_10535
BRB: EH207_11335
BNG: EH206_12170 EH206_14470
BIZ: HC231_09955
LBQ: CKQ53_11480
LPOP: I6N93_06705
SLIG: GTU79_18870
EPE: CI789_12735
ERP: LJN55_06005
EPI: Q3V30_15535
PAO: Pat9b_1046
KLN: LH22_16995
PANS: FCN45_05475
KPIE: N5580_12825
PPHO: CTZ24_05400
PDIP: KFZ74_14540
PANE: P6287_05505
PANZ: NR302_05515
TCI: A7K98_05900
GAI: IMCC3135_12715(ybiC)
LLP: GH975_03415
PSE: NH8B_1101
VOX: LCH97_00155
LHK: LHK_00733
MAER: DAI18_01965
RPJ: N234_10685
REH: H16_B0942(h16_B0942)
CNC: CNE_2c09100
CUH: BJN34_25865
REU: Reut_A1498
RME: Rmet_1634(ybiC)
CTI: RALTA_B0766
CBW: RR42_s1740
CGD: CR3_3549(ybiC)
CCUP: BKK81_30325
CUP: BKK80_26030
CUU: BKK79_31905
CPAU: EHF44_13540
COX: E0W60_18040
CCAM: M5D45_08140
CCAX: KZ686_03800
CUK: KB879_09545
CNAN: A2G96_27955
CUPR: IC580_18455
CUPP: CTP10_R14670
BVI: Bcep1808_5437
BVE: AK36_3467
BUR: Bcep18194_B0783
BCM: Bcenmc03_5376
BCH: Bcen2424_4910
BCJ: BCAM2148
BCEN: DM39_5704
BCEW: DM40_4867
BCEO: I35_6030
BAM: Bamb_4341
BAC: BamMC406_4858
BMJ: BMULJ_04813(ybiC)
BMU: Bmul_3704
BMK: DM80_5086
BMUL: NP80_4847
BCT: GEM_3531
BCED: DM42_5847
BCEP: APZ15_28390
BDL: AK34_3599
BPYR: ABD05_24720
BCON: NL30_01730 NL30_16180
BDF: WI26_23635
BLAT: WK25_26805
BTEI: WS51_07850
BSEM: WJ12_30605
BPSL: WS57_03400
BMEC: WJ16_29210
BSTG: WT74_29735
BSTL: BBJ41_24285
BANN: JFN94_28665
BARI: NLX30_26670
BAEN: L3V59_24980
BSER: R0290_17380
BUG: BC1001_3756
BYI: BYI23_B006540
BUK: MYA_5051
BUQ: AC233_20755
BUM: AXG89_21570
BUI: AX768_24100
BURK: DM992_22225
BURT: BTHE68_32630(ybiC)
BURM: GJG85_21610
BPH: Bphy_5277
BGE: BC1002_4042
BPX: BUPH_00322
BPY: Bphyt_5456
BCAI: K788_0002937
PSPW: BJG93_25975
PARA: BTO02_06355
PHS: C2L64_24685
PTER: C2L65_23600
PGP: CUJ91_22670
PCJ: CUJ87_22265
PTS: CUJ90_29855
PMEG: FNZ07_00650
PGIS: I6I06_23935
PACP: FAZ97_24460
PACS: FAZ98_22870
PEW: KZJ38_17700
PSAA: QEN71_10905
PHUN: U0042_08030
PLAD: PPGU16_39040
PAZZ: PBP221_47660
CABA: SBC2_58360(hcxB)
BUO: BRPE64_BCDS06860(ybiC)
CABK: NK8_35440
BUE: BRPE67_BCDS08850
TVL: FAZ95_33500
BFZ: BAU07_03380
BOZ: DBV39_18870
ODH: DHf2319_09600
RHY: RD110_04390
RHF: EUB48_18815
POL: Bpro_3968
POS: DT070_03385
PVAC: HC248_02881(hcxB_2)
VEI: Veis_1530
VAP: Vapar_0782
VPE: Varpa_0800
VPD: VAPA_1c08430
VAA: AX767_07380
VBO: CKY39_03955
VAM: C4F17_15290
VAZ: H7F35_16055
VAV: IG196_02320
VAE: RZE79_03545
VAX: H7F36_08515
CTEZ: CT3_36280
RTA: Rta_08970
LIM: L103DPR2_00626(ybiC)
LIH: L63ED372_02625(ybiC)
SUTT: SUTMEG_20000
SUTK: FG381_06190
SWS: I6J16_00030
MLO: mlr9117
BJA: bll2917(bll2917)
BJU: BJ6T_67890 BJ6T_68480
BJP: RN69_32930 RN69_33220
BRA: BRADO2597
BBT: BBta_2943
BRS: S23_50980
AOL: S58_50150
BRC: BCCGELA001_13060 BCCGELA001_13315
BRAD: BF49_1720 BF49_1774
BIC: LMTR13_28430
BRO: BRAD285_4739
BRK: CWS35_18135
BOT: CIT37_39020
BRQ: CIT40_09065
BGQ: X265_26365
BGZ: XH91_24600
BSYM: CIT39_08165 CIT39_08460
BBET: F8237_05505
BARH: WN72_16000
BVZ: BRAD3257_5784(ybiC)
BEL: BE61_70620
BDG: LPJ38_17615 LPJ38_17875
BSEP: HAP48_0030810
BQB: J4P68_0032070
BSEI: KMZ68_09630
BBAN: J4G43_016705 J4G43_016990
BCAN: BcanWSM471_13885 BcanWSM471_14145
BAUT: QA635_28615
BBRA: QA636_30500
BGK: IC762_11620
BCOU: IC761_24805
BPAH: QA639_15380
BXN: I3J27_10905
BROS: QUH67_11825 QUH67_30270
BRAZ: LRP30_12450
BOY: LQG66_11350
BRAY: ML401_09910
RPA: TX73_019450
RPB: RPB_1710
RPC: RPC_1699
RPD: RPD_3587
RPT: Rpal_4277
RPX: Rpdx1_1587
RBK: E0H22_18025
RHOR: ONR75_22980
RHOL: RBJ75_00880
VGO: GJW-30_1_02181(ybiC)
TRB: HB776_13875
TALZ: RPMA_20140
TARD: RSO67_07565
BVV: BHK69_19355
BVES: QO058_00810
BOP: AXW83_07660
BOS: BSY19_2656
BOI: BLM15_06645
BOF: FQV39_04075
BOW: NWE53_04840
BOSE: RMR04_14755
STAR: G3545_25755
MRD: Mrad2831_3061
MET: M446_6488
MNO: Mnod_6588
MOR: MOC_3439
MAQU: Maq22A_c16540
MPHY: MCBMB27_02475
MEE: DA075_22540
METX: A3862_16640
MMES: MMSR116_15560
MTEA: DK419_16250
MIND: mvi_46040
MTAD: M6G65_32955
MFUJ: ABC766_24190
MENS: LOK46_16530
MOC: BB934_16735
RHJ: HZY79_01380
PSIN: CAK95_00185
RBM: TEF_07945 TEF_09375
PHR: C6569_08080
PSTG: E8M01_33730
PAQT: E8L99_16820
SIL: SPO1603
LEJ: ETW24_04545
LEIM: K3557_13845
SPOT: G6548_05185
SULB: IV89_002679
SULY: ABM428_04925
SULP: AADW22_04970
ASCA: QEZ52_05480
TSCO: R1T40_21920
MMR: Mmar10_0711
HYT: HXX25_01495
ZMP: Zymop_1077
RAP: RHOA_0566(hcxB) RHOA_1359(hcxB)
RGI: RGI145_06295
ROS: CTJ15_11105
RMUC: FOB66_08110
RMT: IAI58_14260
RFL: Rmf_01580 Rmf_44780
RCV: PFY06_16565
SRF: LHU95_03030 LHU95_11910
ELIO: KO353_01085 KO353_03675 KO353_05605
SHUM: STHU_18420 STHU_40300 STHU_51190
SVC: STVA_34900 STVA_51100
STEL: STAQ_17320 STAQ_46330
AZL: AZL_a00760 AZL_a06180
ALI: AZOLI_p20546
ABS: AZOBR_p130099(ldh)
ABQ: ABAZ39_18425
ABF: AMK58_16305
ATI: AL072_27750
AHU: A6A40_15480
AZT: TSH58p_29005
AZM: DM194_19645 DM194_22170
AZZ: DEW08_01245
AARE: D3093_15450
AZS: E6C72_16090 E6C72_23440
AZP: E6C67_05625
ADJ: ACIU1J_21610
SKT: IGS68_02365
SMUC: JL100_002470
SROE: JL101_023045
FER: FNB15_01600
AALU: ABWI00_10675
NACI: NUH88_01885 NUH88_11400
THAR: T8K17_02885 T8K17_19110
TMO: TMO_0662(ybiC)
HFL: PUV54_01395
SNEA: NBZ79_18745
GAZ: Pan241w_17250(ybiC_1)
GAW: V144x_26030(ybiC_2)
ASOI: MTP13_14750
DNI: HX89_07150
ARS: ADJ73_10745
PDX: Psed_6328
PSDS: K1T35_38760
VER: HUT12_13325
PSUU: Psuf_086470
HALG: HUG10_07180
 » show all
Reference
PMID:8037924
  Authors
Ohmori H
  Title
Structural analysis of the rhlE gene of Escherichia coli.
  Journal
Jpn J Genet 69:1-12 (1994)
DOI:10.1266/jjg.69.1
  Sequence
[eco:b0801]
Reference
PMID:27941785
  Authors
Sevin DC, Fuhrer T, Zamboni N, Sauer U
  Title
Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli.
  Journal
Nat Methods 14:187-194 (2017)
DOI:10.1038/nmeth.4103
  Sequence
[eco:b0801]
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