KEGG   ORTHOLOGY: K14154
Entry
K14154                      KO                                     
Symbol
THI6
Name
thiamine-phosphate diphosphorylase / hydroxyethylthiazole kinase [EC:2.5.1.3 2.7.1.50]
Pathway
map00730  Thiamine metabolism
map01100  Metabolic pathways
map01240  Biosynthesis of cofactors
Module
M00898  Thiamine biosynthesis, pyridoxal-5P => TMP/thiamine/TPP
Reaction
R03223  2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)-thiazole 2-methyl-4-aminopyridine-5-methenyltransferase
R04448  ATP:4-methyl-5-(2-hydroxyethyl)thiazole 2-phosphotransferase
R10712  2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate 2-methyl-4-aminopyrimidine-5-methenyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    K14154  THI6; thiamine-phosphate diphosphorylase / hydroxyethylthiazole kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     K14154  THI6; thiamine-phosphate diphosphorylase / hydroxyethylthiazole kinase
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.50  hydroxyethylthiazole kinase
     K14154  THI6; thiamine-phosphate diphosphorylase / hydroxyethylthiazole kinase
Other DBs
COG: COG0352 COG2145
GO: 0004789 0004417
Genes
SCE: YPL214C(THI6)
SEUB: DI49_5254
SPAO: SPAR_P00620
AGO: AGOS_AFL110C
ERC: Ecym_2185
KLA: KLLA0_B02134g
KMX: KLMA_40552(THI6)
LTH: KLTH0H03784g
VPO: Kpol_1002p43
ZRO: ZYRO0E07216g
CGR: 2887447(THI6)
NCS: NCAS_0A01010(NCAS0A01010)
NDI: NDAI_0F01540(NDAI0F01540)
TPF: TPHA_0J02470(TPHA0J02470)
TBL: TBLA_0A06110(TBLA0A06110)
TGB: HG536_0E05500
TDL: TDEL_0E05400(TDEL0E05400)
KAF: KAFR_0K00230(KAFR0K00230)
KNG: KNAG_0D01040(KNAG0D01040)
ZMK: HG535_0B01000
SLUD: SCDLUD_001118
DHA: DEHA2G01166g
PIC: PICST_77822
PGU: PGUG_04644
SPAA: SPAPADRAFT_140906
LEL: PVL30_001977(THI6)
LBG: 92207611(LODBEIA_P24150)
CAL: CAALFM_C302860WA(THI6)
CTP: CTRG_02560
COT: CORT_0B04690
CDU: CD36_82850
CTEN: 18245501(THI6)
CLU: CLUG_03522
CLUS: A9F13_01g06512
CAUR: CJI96_0003049
ASAU: 88172652(PUMCH_001587)
PPA: PAS_chr3_0843
PKZ: C5L36_0B08970
BNN: FOA43_000319
BBRX: BRETT_000374
OPA: HPODL_01250
YLI: 2909412(YALI2_B00493g)
SLB: AWJ20_724(THI6)
NCR: NCU11173
NTE: NEUTE1DRAFT81844(NEUTE1DRAFT_81844)
SMP: 10808100(SMAC4_02265)
PAN: PODANSg4855
PBEL: QC761_702010(THI6)
PPSD: QC762_702010(THI6)
PPSP: QC763_702010(THI6)
PPSA: QC764_702010(THI6)
TTT: THITE_2119543
MTM: MYCTH_2304176
CTHR: CTHT_0024040
RTHE: 98121791(VTJ83DRAFT_1032)
MGR: MGG_06448
PPEI: PpBr36_06037
PGRI: PgNI_00854
TMN: UCRPA7_1662
SSCK: SPSK_02391
FGR: FGSG_07264
FPU: FPSE_01116
FPOA: FPOAC1_011040
FVN: FVRRES_12059
FVR: FVEG_05316
FOX: FOXG_02153
NHE: NECHADRAFT_68618
FFC: NCS54_00586700
FKR: NCS57_00624400
FMU: J7337_002447
TRE: TRIREDRAFT_75992
TRR: M419DRAFT_5893
TATV: 25778152(TrAtP1_004621)
TASP: 36607096(TrAFT101_004056)
MAW: 19244915(THI6)
MAJ: MAA_05935
MBRN: 26238498(G6M90_00g014690)
PCHM: VFPPC_13327
CMT: CCM_01506
AMUS: LMH87_004190
PLJ: 90642733(PLICBS_003010)
PTKZ: JDV02_000833(THI6)
CFJ: CFIO01_10597
CHIG: CH63R_02669
CDET: 87937412(CDEST_00909)
SAPO: SAPIO_CDS2971
ELA: UCREL1_11567
PFY: PFICI_02731
SSL: SS1G_13563
BFU: BCIN_16g01340(Bcthi6)
MBE: MBM_00376
PSCO: LY89DRAFT_612588
GLZ: GLAREA_11575
ANI: ANIA_10472
AFM: AFUA_2G08970
ACT: ACLA_080810
NFI: NFIA_084530
AOR: AO090011000799
ANG: An12g04660
AFV: AFLA_008192
ALUC: AKAW2_60858A
ACHE: ACHE_50920A
APUU: APUU_40500S
PCS: N7525_003791
PDP: PDIP_84220
POU: POX_f08449
TMF: EYB26_005778
TRG: TRUGW13939_06291
CIM: CIMG_00798
CPW: 9691750(D8B26_002323)
URE: UREG_00763
ABE: ARB_04892
TVE: TRV_07077
PBL: PAAG_02219
PBN: PADG_05357
AJE: HCAG_07304
BGH: BDBG_08049
PNO: SNOG_13715
PTE: PTT_18545
PTRR: 6347611(PtrM4_125270)
BZE: COCCADRAFT_6682
BSC: COCSADRAFT_327297
BOR: COCMIDRAFT_29978
AALT: CC77DRAFT_20111
ADAC: 96085609(ACET3X_005287)
ARAB: EKO05_0011334
ZTR: MYCGRDRAFT_69865
PFJ: MYCFIDRAFT_152334
FFU: CLAFUR5_06100
CBET: CB0940_08542
BCOM: BAUCODRAFT_31607
NPA: UCRNP2_1656
TML: GSTUM_00001710001
SPO: 2541872(thi4)
SOM: SOMG_02003(thi4)
CNE: CNI03710
CNB: CNBH3540
CNG: CNAG_04230
CGI: CGB_H4330W
CDEU: CNBG_2816
CDEP: 91085850(L203_101637)
KMG: 30165955(I203_103439)
KNE: 92181142(IAR55_003884)
CCAC: CcaHIS019_0201870(THI6)
PPL: POSPLDRAFT_22001 POSPLDRAFT_88528
TVS: TRAVEDRAFT_26528
DSQ: DICSQDRAFT_79045
PCO: PHACADRAFT_123292
SHS: STEHIDRAFT_171165
HIR: HETIRDRAFT_452502
PSQ: PUNSTDRAFT_142092
ADL: AURDEDRAFT_55599
FME: FOMMEDRAFT_134198
GTR: GLOTRDRAFT_115373
RSX: RhiXN_07027 RhiXN_10509
LBC: LACBIDRAFT_231927
CCI: CC1G_03317
ABP: AGABI1DRAFT80488(AGABI1DRAFT_80488)
ABV: AGABI2DRAFT229699(AGABI2DRAFT_229699)
PCUB: JR316_0001840
MRR: Moror_17729
MORE: E1B28_010130
SCM: SCHCO_02750201(SCHCODRAFT_02750201)
CPUT: CONPUDRAFT_136170
SLA: SERLADRAFT_348122
WSE: WALSEDRAFT_35249
WIC: J056_004019
UMA: UMAG_02614
PFP: PFL1_01880
SGRA: EX895_005265
MGL: MGL_0253
MRT: MRET_1062
MSYM: MSY001_3360
PGR: PGTG_08842
PTRC: PtA15_15A252
PSTR: Pst134EA_027985 Pst134EA_032194
MLR: MELLADRAFT_63716
ACAN: ACA1_061790
NGR: NAEGRDRAFT_78019
 » show all
Reference
PMID:7982968
  Authors
Nosaka K, Nishimura H, Kawasaki Y, Tsujihara T, Iwashima A
  Title
Isolation and characterization of the THI6 gene encoding a bifunctional thiamin-phosphate pyrophosphorylase/hydroxyethylthiazole kinase from Saccharomyces cerevisiae.
  Journal
J Biol Chem 269:30510-6 (1994)
  Sequence
[sce:YPL214C]
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