KEGG ORTHOLOGY: K15624

KEGG

ORTHOLOGY: K15624

Entry

K15624                      KO

Symbol

SSX

Name

protein SSX

Pathway

Transcriptional misregulation in cancer

Disease

Synovial sarcoma

Spermatogenic failure

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K15624  SSX; protein SSX

Genes

HSA:	10214(SSX3) 280658(SSX7) 548313(SSX4B) 6756(SSX1) 6757(SSX2) 6758(SSX5) 6759(SSX4) 727837(SSX2B)

PTR:	100608018 107966478 129135296 465644 736918(SSX1) 737267 737502 737614(SSX3) 741661

PPS:	100967520 100968329 100968671 100977365 100980673 100995951 117974339 117977594(SSX4B) 129393040

GGO:	101140047 101142537(SSX4) 101151343 101153153 109024635 115930107 115930166 129523569 129529923

PON:	100440684 100441307 100444465 100445071 100449492 100451712 100451987 100457489 100462500 112128549 112130723 112130770 112130964 129047243 129052857 129052917

PPYG:

129024374 129024390 129024391 129024393 129024394 129024460 129024503 129024517 129024575 129024610 129024686 129025032 129025033 129025189 129025294 129025295

NLE:	100580298 100580639 100587351 100593675 100607153 100607493 105737545 115830384 115830472 115833320

HMH:	116811283 116811303 116811652 116811653

SSYN:

129475639 129475650 129476247 129476248 129476250

MCC:	100424446 106995770 106995824 708657 709052 709149 709251 709597(SSX3) 709684 713973

MCF:	102119223 102120735 102121259 102121356 102122019 102122895 102123260 102124177 107126396 123571056

MTHB:

126945626 126945635 126945636 126945638 126945639 126945640 126945641 126945642 126945690 126945763 126945767

MNI:	105493879 105493882 105493883 105493884 105493885 105493888 105493889(SSX3) 105493959 105493961

CSAB:

103231913 103231914 103231918 103231920 103247830

CATY:

105590309 105590480 105590482 105590483 105590484 105590485 105590486 105599662

PANU:

100997105 100998162 101002595 101002941 116271843 116272088 116272089 116272091 116272804

TGE:	112615345(SSX3) 112615346 112615348 112615349 112615351 112615352 112615883 112615921 112616315 112616319

MLEU:

105538467 105541719 105547735 105547737 105547738 105547741 105547755

RRO:	104660672 104660673 104668564 104668565 104675812 104675813 104675814 104675818 104681160 104681161 104681162 115898686

RBB:	108517025 108517026 108517027(SSX1) 108522062 108523255 108523530 108524300

TFN:	117077777 117078020 117089302 117089318 117089333

PTEH:

111533764 111534437 111535301

CANG:

105509486 105509487 105515025 105515026 105515029

CJC:	100397750(SSX4B)

SBQ:	101027607 101046270

ANAN:

105734531 135269931

MMUR:

LCAT:

OGA:

MMU:	387586(Ssxb5)

MCAL:

110287353 110288879

RNO:	691903(Ssx1)

MCOC:

ANU:	117694191 117694192 117694193 117694194 117694389

ASYL:

MUN:

CGE:	100767016 100769405

MAUA:

121135223 121138163

PROB:

PLEU:

AAMP:

NGI:

HGL:

CPOC:

DORD:

PLOP:

NCAR:

MMMA:

ITI:

OCU:

OPI:

TUP:

GVR:

CFA:

CLUD:

VVP:

VLG:

NPO:

AML:

UMR:

UAH:

UAR:

ELK:

LLV:

MPUF:

MNP:	132007145(SSX4)

MLK:

NVS:

ORO:

EJU:

ZCA:

MLX:

NSU:

LWW:

FCA:

PYU:

PCOO:

PBG:

PVIV:

LRUF:

LGF:

AJU:

PTG:

PPAD:

PUC:

HHV:

BTA:

BBUB:

102408220 112582328

BBIS:

CHX:

OAS:

CSUM:

SSC:

CBAI:

CDK:

VPC:

BACU:

BMUS:

118888279 118899009

LVE:	103089327(SSX1)

OOR:

LALB:

DLE:

PCAD:

PSIU:

NASI:

ECB:

EPZ:

EAI:

MYB:

MMYO:

MLF:

MDT:

MYUM:

PKL:

EFUS:

MNA:	107541350 107541351

PHAS:

MMF:	118635444 118635446

PPAM:

HAI:	109374413(SSX7)

RFQ:	117016667 117029707 117032812

PALE:

102881950 102895363

PGIG:

120587104(SSX4) 120610803 120610804

PVP:

RAY:	107504442 107504443 107509349 107509350

MJV:

TOD:

LAV:

ETF:

DNM:	101436407(SSX1)

Reference

Authors

Crew AJ, Clark J, Fisher C, Gill S, Grimer R, Chand A, Shipley J, Gusterson BA, Cooper CS

Title

Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.

Journal

EMBO J 14:2333-40 (1995)
DOI:10.1002/j.1460-2075.1995.tb07228.x

Sequence

[hsa:6756 6757]

Reference

Authors

Yano M, Toyooka S, Tsukuda K, Dote H, Morimoto Y, Ohata N, Ichimura K, Aoe M, Date H, Shimizu N

Title

SYT-SSX fusion genes in synovial sarcoma of the thorax.

Journal

Lung Cancer 44:391-7 (2004)
DOI:10.1016/j.lungcan.2003.11.011

Reference

Authors

Haldar M, Randall RL, Capecchi MR

Title

Synovial sarcoma: from genetics to genetic-based animal modeling.

Journal

Clin Orthop Relat Res 466:2156-67 (2008)
DOI:10.1007/s11999-008-0340-2

LinkDB

DBGET integrated database retrieval system