KEGG   ORTHOLOGY: K20331
Entry
K20331                      KO                                     
Symbol
toxA
Name
toxoflavin synthase [EC:2.1.1.349]
Pathway
map02024  Quorum sensing
Reaction
R12157  S-adenosyl-L-methionine:1,6-didemethyltoxoflavin N6-methyltransferase (reumycin-forming)
R12158  S-adenosyl-L-methionine:reumycin N1-methyltransferase (toxoflavin-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   02024 Quorum sensing
    K20331  toxA; toxoflavin synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.349  toxoflavin synthase
     K20331  toxA; toxoflavin synthase
Other DBs
COG: COG2226
Genes
SYM: K6K13_17790
YAK: ACZ76_13200 ACZ76_16160
SFJ: SAMEA4384070_2573
SOF: NCTC11214_04378(bioC_2)
PLU: plu0250
PLUM: A4R40_01225
PAY: PAU_03241
PTT: VY86_11790
PAKH: B0X70_01085
PLUI: CE143_01085
XBO: XBJ1_1516 XBJ1_2779
XBV: XBW1_0361 XBW1_0364 XBW1_3521
XNE: XNC1_1384 XNC1_2019 XNC1_2445
XNM: XNC2_1346 XNC2_1954 XNC2_2352
XDO: XDD1_1102(toxA) XDD1_1316 XDD1_1320 XDD1_1508
XPO: XPG1_2381 XPG1_2700
XHO: A9255_09690 A9255_16450
XBU: HGO23_08785 HGO23_13520
XGR: QL128_13470
PALA: CO695_02920
BUJ: BurJV3_3707
STEN: CCR98_18885
STEQ: ICJ04_13845
LAB: LA76x_0657
LAQ: GLA29479_2850
LCP: LC55x_4965
LEZ: GLE_0529
LYA: RDV84_03775
VNP: KW548_07795
PMOL: CLJ08_02150
PMOS: O165_012485
PFL: PFL_1036
PPRC: PFLCHA0_c10560(toxA)
PPRO: PPC_1074
PMUD: NCTC8068_03529(toxA)
PLQ: AA042_15235
PPV: NJ69_03265
PSEC: CCOS191_2151
PYM: AK972_5317
PDW: BV82_3620
PXN: HU772_015150
PMUY: KSS95_17865
PMAM: KSS90_10405
PTK: EXN22_17150
PTAE: NCTC10697_01384(toxA)
PQE: OSC50_19365
PBEZ: SBP02_01345
MCA: MCA0484
MMEO: OOT43_09550
CYS: NYP54_04445
TTI: THITH_10570
HCS: FF32_13340
HAMS: NF683_14940
HVN: EI420_07645
ADI: B5T_03651
ENW: MJO57_09165
ENG: O2T12_06780
BDL: AK34_1842 AK34_3761
BGL: bglu_2g06400
BGU: KS03_5278
BGD: bgla_1g04570
BGO: BM43_1844
ALCN: MID00_03025
BIC: LMTR13_24470
BRAZ: LRP30_33270
MSC: BN69_1794
MBRY: B1812_13435
MROS: EHO51_00310
MESZ: LNB28_07680
AZZ: DEW08_24275
SNEA: NBZ79_02900
MSD: MYSTI_02000 MYSTI_05830
MFB: MFUL124B02_06660 MFUL124B02_28840
MLAN: JY572_16765 JY572_37775
CCX: COCOR_03369(ubiG4) COCOR_05983
PPAK: JY651_27915 JY651_27950
SUR: STAUR_6832
AGE: AA314_07139
AVM: JQX13_49480
MBD: MEBOL_006373 MEBOL_006914
CFUS: CYFUS_003503 CYFUS_005489 CYFUS_008555
SCU: SCE1572_20315
CCRO: CMC5_053700(ubiE) CMC5_062770(smtA) CMC5_062800(smtA)
PAUU: E8A73_009980 E8A73_016780
MRM: A7982_08219 A7982_13440
PUO: RZN69_06215
GMR: GmarT_49760(novO)
GIM: F1728_20575
GPN: Pan110_07630(couO) Pan110_49510(bioC_2)
GFM: Enr17x_49740(bioC_2)
GAZ: Pan241w_48900(ubiE_6)
GAW: V144x_12750(bioC_1) V144x_47950(ubiG_3)
GAX: Pan161_49930(bioC)
SDYN: Mal52_05470(novO)
PVAR: SH412_001230
SRHO: HH216_19135
RSI: Runsl_2309
RUP: DTQ70_28135
FIB: A6C57_23755
HTS: HMJ29_00435
NNEO: PQG83_16570
MUL: MUL_2739
MMI: MMAR_3525 MMAR_3636 MMAR_4425
MMAE: MMARE11_34420 MMARE11_35440 MMARE11_42500
MLI: MULP_03780
MPSE: MPSD_36050 MPSD_45780
MSHO: MSHO_02170 MSHO_49470
MSPG: F6B93_11885 F6B93_14415
NBR: O3I_015605
NTP: CRH09_33970
NVU: V7968_16015 V7968_23400
RHW: BFN03_03385
PDEF: P9209_25820
PSOW: ABI214_10555
SVE: SVEN_3943
SDV: BN159_1463
SALS: SLNWT_7298
SVT: SVTN_29985
STRE: GZL_00343
SLD: T261_1553
SLC: SL103_16730
STRM: M444_06095 M444_32570 M444_36500
SRW: TUE45_01220(ubiG_1)
SGS: AVL59_28695
SALU: DC74_8060
SALL: SAZ_41625
SGV: B1H19_33505
SALF: SMD44_00437
SALJ: SMD11_0158 SMD11_6408 SMD11_6799
SLX: SLAV_32705
STRO: STRMOE7_02825
SFK: KY5_0115
SKA: CP970_42325
SGZ: C0216_16250 C0216_18680
SVN: CP980_29715 CP980_30410
SRK: FGW37_30550 FGW37_30570 FGW37_30610
SFIC: EIZ62_09530 EIZ62_31840
SVR: CP971_30390
SAQU: EJC51_40760
SBY: H7H31_01780 H7H31_22130
SRIM: CP984_06170 CP984_29705
SSUB: CP968_01295 CP968_29700 CP968_29830
SCIN: CP977_28300
SCHA: CP983_20860
SGX: H4W23_13750
SSPB: CP982_02060 CP982_05925 CP982_28355
SNF: JYK04_01385(bchM)
SHUN: DWB77_07165(ubiG_5)
SCYG: S1361_01915
SFEU: IM697_31080
SPEU: CGZ69_35255
SROI: IAG44_03755
SXN: IAG42_30705
SACT: DMT42_14735
SYAN: NRK68_03720 NRK68_30885
STAA: LDH80_09125
SNIG: HEK616_78900
SCIR: STRCI_007059
SXT: KPP03845_100538(ind7) KPP03845_101123(ubiE_1)
SLON: LGI35_04610
SGK: PET44_04660 PET44_31010 PET44_33940
SHAU: K9S39_09015 K9S39_11160
SFP: QUY26_08880
SCHG: NRO40_24290
STTN: BSL84_03475 BSL84_30735
STRZ: OYE22_01790 OYE22_21305
STPB: QR97_12365
SCAJ: O1G22_41205
STII: DRB96_32685 DRB96_41015
STIC: DRB89_32400 DRB89_40720
SABD: N8I86_36180
SCT: SCAT_5482 SCAT_p1624
SCY: SCATT_54800 SCATT_p01000
KSK: KSE_73110
KAU: B6264_23650
ACIR: OG979_18850
SEN: SACE_7128
AMYC: CU254_04900
ARHD: VSH64_00990
AMOG: QRX60_44205
ACOR: LCL61_32800
AMYZ: HUW46_01027(ubiG_1) HUW46_04136(ubiG_3)
ACAB: QRX50_45200
AMYD: K1T34_29865
AMYE: MJQ72_05185
AMYS: CVV72_17485
APRE: CNX65_23095
AMI: Amir_4628
SESP: BN6_45550
SSYI: EKG83_21765
KUT: JJ691_05120(coq3_1) JJ691_36530(coq3_4)
KBR: Q4V65_05215 Q4V65_42725
KPHY: AOZ06_29455 AOZ06_31565
LED: BBK82_13205
ACTU: Actkin_03411
UME: RM788_05655
PLAB: C6361_36195
PLAT: C6W10_33740
SYNE: Syn6312_3678
SYNZ: H8F24_03050
CYN: Cyan7425_0895 Cyan7425_3410
CYC: PCC7424_0911
OXY: HCG48_13190
ANB: ANA_C12771
DHT: NG743_22140
DOZ: HEP80_08920
DOC: HEQ26_22540
STOQ: K2F26_05955
SKV: NIES73_00310
OCF: WJM97_04525
SCYT: SAMD_20430
SCYS: NIES4073_12120 NIES4073_76070
 » show all
Reference
PMID:15522077
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
  Sequence
[bgl:bglu_2g06400]
Reference
PMID:27070241
  Authors
Fenwick MK, Philmus B, Begley TP, Ealick SE
  Title
Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
  Journal
Biochemistry 55:2748-59 (2016)
DOI:10.1021/acs.biochem.6b00167
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