KEGG   ORTHOLOGY: K21037
Entry
K21037                      KO                                     
Symbol
P
Name
Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H [EC:2.7.7.7 2.7.7.49 3.1.26.4]
Pathway
map03230  Viral genome structure
map03240  Viral replication
map03272  Virion - Hepatitis viruses
map05161  Hepatitis B
Network
nt06162  Hepatitis B virus (HBV)
nt06263  Hepatocellular carcinoma
nt06517  TLR signaling
  Element
N00552  HBV pol to TLR3-IRF3 signaling pathway
N00558  HBV pol to IFN signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K21037  P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H
   03240 Viral replication
    K21037  P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H
   03272 Virion - Hepatitis viruses
    K21037  P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    K21037  P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K21037  P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     K21037  P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H
    2.7.7.49  RNA-directed DNA polymerase
     K21037  P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.26  Endoribonucleases producing 5'-phosphomonoesters
    3.1.26.4  ribonuclease H
     K21037  P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H
Viral proteins [BR:ko03200]
 dsDNA-RT viruses
  Hepatitis B virus
   K21037  P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H
DNA polymerases [br01612.html]
 DNA polymerases in prokaryotes, eukaryotes and viruses
  K21037
Other DBs
GO: 0003887 0003964 0004523
Genes
VG: 11538203(PaHBV_gp3) 1488459(GSHVgp2) 15042019(K202_gp1) 19737426(HM84_gp1) 19737431(HM82_gp1) 19737436(HM83_gp1) 2545285(QJ946_gp2) 2546414(DHBVgp4) 2546416(DHBVgp3) 2546421(WhBvgp1) 26039966(wsHBV_gp2) 26101580(AR657_gp1) 2703545(HHBVgp3) 2943190(SGHBVgp3) 2943453(SHBV_gp3) 33350088(CGU75_gp3) 37617584(D1R25_gp1) 37627713(BBA91_gp4) 37627719(BBC22_gp2) 40526806(FLA63_gp1) 4097842(RGHBVp2) 41701927(EXK74_gp1) 80512040(QJ741_gp1) 80512045(QJ742_gp1) 80533906(QKJ89_gp1) 80533931(QKJ93_gp1) 944565(P)
Reference
PMID:2153228
  Authors
Radziwill G, Tucker W, Schaller H
  Title
Mutational analysis of the hepatitis B virus P gene product: domain structure and RNase H activity.
  Journal
J Virol 64:613-20 (1990)
DOI:10.1128/JVI.64.2.613-620.1990
  Sequence
[vg:944565]
Reference
PMID:27440888
  Authors
Unchwaniwala N, Sherer NM, Loeb DD
  Title
Hepatitis B Virus Polymerase Localizes to the Mitochondria, and Its Terminal Protein Domain Contains the Mitochondrial Targeting Signal.
  Journal
J Virol 90:8705-19 (2016)
DOI:10.1128/JVI.01229-16
  Sequence
[vg:944565]
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