KEGG   ORTHOLOGY: K21927
Entry
K21927                      KO                                     
Symbol
COP3
Name
alpha-muurolene/germacrene-A/gamma-muurolene/(+)-delta-cadinol synthase [EC:4.2.3.125 4.2.3.23 4.2.3.126 4.2.3.212]
Pathway
map00909  Sesquiterpenoid and triterpenoid biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R07649  2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00909 Sesquiterpenoid and triterpenoid biosynthesis
    K21927  COP3; alpha-muurolene/germacrene-A/gamma-muurolene/(+)-delta-cadinol synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.3  Acting on phosphates
    4.2.3.23  germacrene-A synthase
     K21927  COP3; alpha-muurolene/germacrene-A/gamma-muurolene/(+)-delta-cadinol synthase
    4.2.3.125  alpha-muurolene synthase
     K21927  COP3; alpha-muurolene/germacrene-A/gamma-muurolene/(+)-delta-cadinol synthase
    4.2.3.126  gamma-muurolene synthase
     K21927  COP3; alpha-muurolene/germacrene-A/gamma-muurolene/(+)-delta-cadinol synthase
    4.2.3.212  (+)-delta-cadinol synthase
     K21927  COP3; alpha-muurolene/germacrene-A/gamma-muurolene/(+)-delta-cadinol synthase
Other DBs
GO: 0034005
Genes
DFR: 124500479
TVS: TRAVEDRAFT_75578
DSQ: DICSQDRAFT_124305
SHS: STEHIDRAFT_45387
HIR: HETIRDRAFT_167573
FME: FOMMEDRAFT_109318
GTR: GLOTRDRAFT_103889
CCI: CC1G_12294
ABP: AGABI1DRAFT46681(AGABI1DRAFT_46681)
ABV: AGABI2DRAFT73543(AGABI2DRAFT_73543)
PCUB: JR316_0003914
MPR: MPER_06109
MRR: Moror_15644 Moror_7733
MORE: E1B28_009287(COP3)
AG: AMW90891
 » show all
Reference
PMID:20889795
  Authors
Lopez-Gallego F, Wawrzyn GT, Schmidt-Dannert C
  Title
Selectivity of fungal sesquiterpene synthases: role of the active site's H-1 alpha loop in catalysis.
  Journal
Appl Environ Microbiol 76:7723-33 (2010)
DOI:10.1128/AEM.01811-10
  Sequence
[cci:CC1G_12294]
Reference
PMID:27038475 (4.2.3.212)
  Authors
Zhou H, Yang YL, Zeng J, Zhang L, Ding ZH, Zeng Y.
  Title
Identification and Characterization of a delta-Cadinol Synthase Potentially Involved in the Formation of Boreovibrins in Boreostereum vibrans of Basidiomycota.
  Journal
Nat Prod Bioprospect 6:167-71 (2016)
DOI:10.1007/s13659-016-0096-4
  Sequence
[ag:AMW90891]
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