KEGG   ORTHOLOGY: K25959
Entry
K25959                      KO                                     
Symbol
CYP85A3
Name
brassinosteroid 6-oxygenase / brassinolide synthase [EC:1.14.14.179 1.14.14.180]
Pathway
map00905  Brassinosteroid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00371  Castasterone biosynthesis, campesterol => castasterone
Reaction
R07450  6-deoxocastasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (6alpha-hydroxylating)
R07451  6alpha-hydroxy-castasterone,NADPH---hemoprotein reductase:oxygen 6-oxidoreductase
R07471  castasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (lactonizing, brassinolide-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00905 Brassinosteroid biosynthesis
    K25959  CYP85A3; brassinosteroid 6-oxygenase / brassinolide synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K25959  CYP85A3; brassinosteroid 6-oxygenase / brassinolide synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.179  brassinosteroid 6-oxygenase
     K25959  CYP85A3; brassinosteroid 6-oxygenase / brassinolide synthase
    1.14.14.180  brassinolide synthase
     K25959  CYP85A3; brassinosteroid 6-oxygenase / brassinolide synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP85 family
   K25959  CYP85A3; brassinosteroid 6-oxygenase / brassinolide synthase
Genes
SLY: 100136888(CYP85A3)
SPEN: 107010718
SOT: 102599687
SSTN: 125848344
SDUL: 129874522
CANN: 107861006
Reference
  Authors
Nomura T, Kushiro T, Yokota T, Kamiya Y, Bishop GJ, Yamaguchi S
  Title
The last reaction producing brassinolide is catalyzed by cytochrome P-450s, CYP85A3 in tomato and CYP85A2 in Arabidopsis.
  Journal
J Biol Chem 280:17873-9 (2005)
DOI:10.1074/jbc.M414592200
  Sequence
[sly:100136888]
LinkDB

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