KEGG   NETWORK: N00543
Entry
N00543                      Network                                
Name
HBV HBx to JNK signaling pathway
Definition
X -> JNK -> JUN
  Expanded
K21854 -> (5599,5601,5602) -> 3725
Class
nt06263 Hepatocellular carcinoma
nt06162 Hepatitis B virus (HBV)
Type
Pathogen
Pathway
hsa05161  Hepatitis B
Disease
H00048  Hepatocellular carcinoma
Gene
5599  MAPK8; mitogen-activated protein kinase 8
5601  MAPK9; mitogen-activated protein kinase 9
5602  MAPK10; mitogen-activated protein kinase 10
3725  JUN; Jun proto-oncogene, AP-1 transcription factor subunit
Perturbant
K21854 (X)  X; HBV protein X
Reference
PMID:12686421
  Authors
Panteva M, Korkaya H, Jameel S
  Title
Hepatitis viruses and the MAPK pathway: is this a survival strategy?
  Journal
Virus Res 92:131-40 (2003)
DOI:10.1016/S0168-1702(02)00356-8
Reference
PMID:8764004
  Authors
Benn J, Su F, Doria M, Schneider RJ
  Title
Hepatitis B virus HBx protein induces transcription factor AP-1 by activation of extracellular signal-regulated and c-Jun N-terminal mitogen-activated protein kinases.
  Journal
J Virol 70:4978-85 (1996)
DOI:10.1128/JVI.70.8.4978-4985.1996
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