KEGG   REACTION: R00706
Entry
R00706                      Reaction                               
Name
3-oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating)
Definition
3-Oxopropanoate + CoA + NADP+ <=> Acetyl-CoA + CO2 + NADPH + H+
Equation
C00222 + C00010 + C00006 <=> C00024 + C00011 + C00005 + C00080
Comment
NAD+ (see R00705)
Reaction class
RC00001  C00005_C00006
RC00004  C00010_C00024
RC02723  C00024_C00222
Enzyme
1.2.1.18
Pathway
rn00410  beta-Alanine metabolism
rn00562  Inositol phosphate metabolism
rn00640  Propanoate metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00013  Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA
M00991  Dimethylsulfoniopropionate (DMSP) degradation, cleavage pathway, DMSP => acetyl-CoA
M00992  Dimethylsulfoniopropionate (DMSP) degradation, cleavage pathway, DMSP => acrylate => acetyl-CoA
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.18
     R00706  3-Oxopropanoate + CoA + NADP+ <=> Acetyl-CoA + CO2 + NADPH + H+
Orthology
K00140  malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Other DBs
RHEA: 22991
LinkDB

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