KEGG   REACTION: R04307
Entry
R04307                      Reaction                               
Name
trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase
Definition
trans-4-Hydroxycyclohexanecarboxylate + NAD+ <=> 4-Oxocyclohexanecarboxylate + NADH + H+
Equation
C04404 + C00003 <=> C03767 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00144  C03767_C04404
Enzyme
1.1.1.226
Pathway
rn00362  Benzoate degradation
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.226
     R04307  trans-4-Hydroxycyclohexanecarboxylate + NAD+ <=> 4-Oxocyclohexanecarboxylate + NADH + H+
Orthology
K27673  trans-4-hydroxycyclohexanecarboxylate dehydrogenase [EC:1.1.1.226]
Reference
1  [PMID:34583900]
  Authors
Yamamoto T, Hasegawa Y, Lau PCK, Iwaki H
  Title
Identification and characterization of a chc gene cluster responsible for the aromatization pathway of cyclohexanecarboxylate degradation in Sinomonas cyclohexanicum ATCC 51369.
  Journal
J Biosci Bioeng 132:621-629 (2021)
DOI:10.1016/j.jbiosc.2021.08.013
Other DBs
RHEA: 17432
LinkDB

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