| Entry |
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| Name |
[enzyme]-S-sulfanylcysteine:tRNA-uridine sulfurtransferase (ATP-hydrolysing)
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| Definition |
tRNA uridine + [Enzyme]-S-sulfanylcysteine + ATP <=> tRNA containing 2-thiouridine + [Enzyme]-cysteine + AMP + Diphosphate
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| Equation |
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| Comment |
multi-step reaction
incomplete reaction (donor is unidentified in vivo, dithiothreitol[CPD: C00265] in vitro)
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| Reaction class |
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| Enzyme |
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| Brite |
Enzymatic reactions [BR:br08201]
2. Transferase reactions
2.8 Transferring sulfur-containing groups
2.8.1 Sulfurtransferases
2.8.1.13
R08700 tRNA uridine + [Enzyme]-S-sulfanylcysteine + ATP <=> tRNA containing 2-thiouridine + [Enzyme]-cysteine + AMP + Diphosphate
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| Orthology |
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| Reference |
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| Authors |
Kambampati R, Lauhon CT. |
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| Title |
MnmA and IscS are required for in vitro 2-thiouridine biosynthesis in Escherichia coli. |
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| Journal |
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| LinkDB |
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