KEGG   REACTION: R08958
Entry
R08958                      Reaction                               
Name
5alpha-pregnan-20alpha-ol-3-one:NADP+ 20-oxidoreductase
Definition
5alpha-Pregnan-20alpha-ol-3-one + NADP+ <=> 5alpha-Pregnane-3,20-dione + NADPH + H+
Equation
C18041 + C00006 <=> C03681 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00139  C03681_C18041
Enzyme
1.1.1.149
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.149
     R08958  5alpha-Pregnan-20alpha-ol-3-one + NADP+ <=> 5alpha-Pregnane-3,20-dione + NADPH + H+
Orthology
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K05295  20alpha-hydroxysteroid dehydrogenase [EC:1.1.1.149]
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