KEGG   REACTION: R10089
Entry
R10089                      Reaction                               
Name
D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5'-phosphate-lyase (glutamine-hydrolyzing)
Definition
D-Ribose 5-phosphate + D-Glyceraldehyde 3-phosphate + L-Glutamine <=> Pyridoxal phosphate + L-Glutamate + 3 H2O + Orthophosphate
Equation
C00117 + C00118 + C00064 <=> C00018 + C00025 + 3 C00001 + C00009
Comment
two-step reaction (see R00256+R10088)
Reaction class
RC00010  C00025_C00064
RC01783  C00018_C00118
RC03049  C00018_C00117
Enzyme
4.3.3.6
Pathway
rn00750  Vitamin B6 metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00916  Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.3  Carbon-nitrogen lyases
   4.3.3  Amine-lyases
    4.3.3.6
     R10089  D-Ribose 5-phosphate + D-Glyceraldehyde 3-phosphate + L-Glutamine <=> Pyridoxal phosphate + L-Glutamate + 3 H2O + Orthophosphate
Orthology
K06215  pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
K08681  pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
Other DBs
RHEA: 31510
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