KEGG   Bos taurus (cow): 282589
Entry
282589            CDS       T01008                                 
Symbol
HSD11B1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1
  KO
K15680  corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
Organism
bta  Bos taurus (cow)
Pathway
bta00140  Steroid hormone biosynthesis
bta00980  Metabolism of xenobiotics by cytochrome P450
bta01100  Metabolic pathways
bta05204  Chemical carcinogenesis - DNA adducts
Module
bta_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    282589 (HSD11B1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    282589 (HSD11B1)
Enzymes [BR:bta01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.146  11beta-hydroxysteroid dehydrogenase
     282589 (HSD11B1)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR DUF1776 THF_DHG_CYH_C 2-Hacid_dh_C Pyr_redox_2 Shikimate_DH Pyr_redox_3 NAD_binding_2 Methyltransf_25 FMO-like Pyr_redox ADH_zinc_N
Other DBs
NCBI-GeneID: 282589
NCBI-ProteinID: NP_001116504
BGD-bta: BT25831
Ensembl: ENSBTAG00000015086
VGNC: 29965
UniProt: Q8HZJ8
LinkDB
Position
16:complement(73564340..73640701)
AA seq 292 aa
MAFMKKYLLPILGIFLAYYYYSANEEFRPEMLRGKRVIVTGASKGIGREMAYHLARMGAH
VVVTARSEESLKKVVSRCLELGAASAHYVAGTMENMTFAEQFVAKAGELVGGLDMLILNH
IHYTPLGVFSNDIHLLRRTLEVNLLSYVVLSTAALPMLKQTNGSIVVVSSIAGKIACPLV
AAYSASKFALDGFFSSLRMEYEATKVNVSITLCILGLIDTDTAMKAVAGIFNAKASPKEE
CALEIIKGGTLRQDEVYYDSSILTPLLLRNPGRKIMEFFFLKKYNMERFINN
NT seq 879 nt   +upstreamnt  +downstreamnt
atggcttttatgaaaaaatacctcctccccatcctggggatcttcttggcctactactac
tattctgcgaatgaggaattcagaccagagatgcttcgaggaaagagagtgattgtcacg
ggggccagcaagggaatcggaagagaaatggcctatcacctggcaaggatgggagcacat
gtggtagtgacagcgaggtcagaagaaagtctaaagaaggtggtatcccgctgcctggag
ctgggggcggcctcagcacactacgtggcgggcaccatggagaacatgaccttcgcagaa
caatttgttgccaaagctggagagctcgtggggggacttgacatgctcattctcaaccac
atccactacacgcctttgggggtgtttagcaatgacatccatctcttgcgcagaaccctg
gaggtcaaccttctgagttatgtggtcctgagcacagccgccttgcccatgctgaagcag
accaacgggagcattgtggtcgtctcctccatagccgggaaaatagcttgtccacttgtt
gctgcgtattctgcaagcaagtttgctctggatgggttcttctcctctctcaggatggaa
tatgaggcgaccaaggtcaatgtgtcaatcaccctctgtattcttggcctcatcgacaca
gacacagccatgaaggcagttgctgggatatttaatgcaaaagcatctccaaaggaagaa
tgtgccctggagattatcaaagggggaactctgcgccaagatgaagtatattatgacagt
tcaatcttgactcctctcctgctgagaaatccaggaaggaagatcatggaatttttcttc
ttgaagaaatataatatggaaagatttataaacaactag

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