Homo sapiens (human): 5476
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Entry
5476 CDS
T01001
Symbol
CTSA, GLB2, GSL, NGBE, PPCA, PPGB
Name
(RefSeq) cathepsin A
KO
K13289
cathepsin A (carboxypeptidase C) [EC:
3.4.16.5
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04142
Lysosome
hsa04614
Renin-angiotensin system
Disease
H00276
Galactosialidosis
H00422
Glycoproteinoses
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
5476 (CTSA)
09150 Organismal Systems
09152 Endocrine system
04614 Renin-angiotensin system
5476 (CTSA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
5476 (CTSA)
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
hsa03110
]
5476 (CTSA)
04131 Membrane trafficking [BR:
hsa04131
]
5476 (CTSA)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
5476 (CTSA)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.16 Serine-type carboxypeptidases
3.4.16.5 carboxypeptidase C
5476 (CTSA)
Peptidases and inhibitors [BR:
hsa01002
]
Serine peptidases
Family S10
5476 (CTSA)
Chaperones and folding catalysts [BR:
hsa03110
]
Intramolecular chaperones
Other peptidases
5476 (CTSA)
Membrane trafficking [BR:
hsa04131
]
Autophagy
Chaperone mediated autophagy (CMA)
Other CMA associated proteins
5476 (CTSA)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
5476 (CTSA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_S10
Motif
Other DBs
NCBI-GeneID:
5476
NCBI-ProteinID:
NP_000299
OMIM:
613111
HGNC:
9251
Ensembl:
ENSG00000064601
UniProt:
P10619
X6R8A1
Structure
PDB
PDBj
LinkDB
All DBs
Position
20:45891335..45898820
Genome browser
AA seq
480 aa
AA seq
DB search
MIRAAPPPLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSK
HLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLI
ANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYA
GIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHC
CSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQD
LGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWD
MCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKME
VQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgatccgagccgcgccgccgccgctgttcctgctgctgctgctgctgctgctgctagtg
tcctgggcgtcccgaggcgaggcagcccccgaccaggacgagatccagcgcctccccggg
ctggccaagcagccgtctttccgccagtactccggctacctcaaaggctccggctccaag
cacctccactactggtttgtggagtcccagaaggatcccgagaacagccctgtggtgctt
tggctcaatgggggtcccggctgcagctcactagatgggctcctcacagagcatggcccc
ttcctggtccagccagatggtgtcaccctggagtacaacccctattcttggaatctgatt
gccaatgtgttatacctggagtccccagctggggtgggcttctcctactccgatgacaag
ttttatgcaactaatgacactgaggtcgcccagagcaattttgaggcccttcaagatttc
ttccgcctctttccggagtacaagaacaacaaacttttcctgaccggggagagctatgct
ggcatctacatccccaccctggccgtgctggtcatgcaggatcccagcatgaaccttcag
gggctggctgtgggcaatggactctcctcctatgagcagaatgacaactccctggtctac
tttgcctactaccatggccttctggggaacaggctttggtcttctctccagacccactgc
tgctctcaaaacaagtgtaacttctatgacaacaaagacctggaatgcgtgaccaatctt
caggaagtggcccgcatcgtgggcaactctggcctcaacatctacaatctctatgccccg
tgtgctggaggggtgcccagccattttaggtatgagaaggacactgttgtggtccaggat
ttgggcaacatcttcactcgcctgccactcaagcggatgtggcatcaggcactgctgcgc
tcaggggataaagtgcgcatggaccccccctgcaccaacacaacagctgcttccacctac
ctcaacaacccgtacgtgcggaaggccctcaacatcccggagcagctgccacaatgggac
atgtgcaactttctggtaaacttacagtaccgccgtctctaccgaagcatgaactcccag
tatctgaagctgcttagctcacagaaataccagatcctattatataatggagatgtagac
atggcctgcaatttcatgggggatgagtggtttgtggattccctcaaccagaagatggag
gtgcagcgccggccctggttagtgaagtacggggacagcggggagcagattgccggcttc
gtgaaggagttctcccacatcgcctttctcacgatcaagggcgccggccacatggttccc
accgacaagcccctcgctgccttcaccatgttctcccgcttcctgaacaagcagccatac
tga
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