Homo sapiens (human): 5915
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Entry
5915 CDS
T01001
Symbol
RARB, HAP, MCOPS12, NR1B2, RARbeta, RARbeta1, RRB2
Name
(RefSeq) retinoic acid receptor beta
KO
K08528
retinoic acid receptor beta
Organism
hsa
Homo sapiens (human)
Pathway
hsa05200
Pathways in cancer
hsa05222
Small cell lung cancer
hsa05223
Non-small cell lung cancer
hsa05226
Gastric cancer
Disease
H00014
Non-small cell lung cancer
H00018
Gastric cancer
H02170
Microphthalmia, syndromic
Drug target
Acitretin:
D02754
<US>
Adapalene:
D01112
<JP/US>
Alitretinoin:
D02815
<US>
Etretinate:
D00316
<JP>
Fenretinide:
D04162
Isotretinoin (
DG00434
):
D00348
<US>
D04636
Retinol (vit A) (
DG00123
):
D00164
<JP/US>
D01621
D06543
<JP>
D08477
Tazarotene:
D01132
<US>
Tretinoin (
DG00433
):
D00094
<JP/US>
D01516
<JP>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
5915 (RARB)
09162 Cancer: specific types
05226 Gastric cancer
5915 (RARB)
05222 Small cell lung cancer
5915 (RARB)
05223 Non-small cell lung cancer
5915 (RARB)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
5915 (RARB)
09183 Protein families: signaling and cellular processes
03310 Nuclear receptors [BR:
hsa03310
]
5915 (RARB)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Zinc finger
Cys4 thyroid hormone receptor-like
5915 (RARB)
Nuclear receptors [BR:
hsa03310
]
1. Thyroid hormone like
1B. Retinoic acid receptor (RAR)
5915 (RARB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
zf-C4
Hormone_recep
Topoisom_I_N
Motif
Other DBs
NCBI-GeneID:
5915
NCBI-ProteinID:
NP_001277145
OMIM:
180220
HGNC:
9865
Ensembl:
ENSG00000077092
UniProt:
P10826
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:24829321..25597932
Genome browser
AA seq
455 aa
AA seq
DB search
MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPAT
IETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
IYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEM
TAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIV
EFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALK
IYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGH
EPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccagcggccacgcatgtccggtcccagcagtgaacggacacatgactcactat
ccagccacaccctacccgttactctttccacctgtcatcggaggactttccctgcctccc
ctccatggccttcatggacatccgcctccgagtggatgcagcaccccgtcgccggcaaca
attgaaacacagagcaccagctctgaggaactcgtcccaagccccccatctccacttcct
ccccctcgagtgtacaaaccctgcttcgtctgccaggacaaatcatcagggtaccactat
ggggtcagcgcctgtgagggatgtaagggctttttccgcagaagtattcagaagaatatg
atttacacttgtcaccgagataagaactgtgttattaataaagtcaccaggaatcgatgc
caatactgtcgactccagaagtgctttgaagtgggaatgtccaaagaatctgtcaggaat
gacaggaacaagaaaaagaaggagacttcgaagcaagaatgcacagagagctatgaaatg
acagctgagttggacgatctcacagagaagatccgaaaagctcaccaggaaactttccct
tcactctgccagctgggtaaatacaccacgaattccagtgctgaccatcgagtccgactg
gacctgggcctctgggacaaattcagtgaactggccaccaagtgcattattaagatcgtg
gagtttgctaaacgtctgcctggtttcactggcttgaccatcgcagaccaaattaccctg
ctgaaggccgcctgcctggacatcctgattcttagaatttgcaccaggtataccccagaa
caagacaccatgactttctcagacggccttaccctaaatcgaactcagatgcacaatgct
ggatttggtcctctgactgaccttgtgttcacctttgccaaccagctcctgcctttggaa
atggatgacacagaaacaggccttctcagtgccatctgcttaatctgtggagaccgccag
gaccttgaggaaccgacaaaagtagataagctacaagaaccattgctggaagcactaaaa
atttatatcagaaaaagacgacccagcaagcctcacatgtttccaaagatcttaatgaaa
atcacagatctccgtagcatcagtgctaaaggtgcagagcgtgtaattaccttgaaaatg
gaaattcctggatcaatgccacctctcattcaagaaatgctggagaattctgaaggacat
gaacccttgaccccaagttcaagtgggaacacagcagagcacagtcctagcatctcaccc
agctcagtggaaaacagtggggtcagtcagtcaccactcgtgcaataa
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