Homo sapiens (human): 6897
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Entry
6897 CDS
T01001
Symbol
TARS1, TARS, TTD7, ThrRS
Name
(RefSeq) threonyl-tRNA synthetase 1
KO
K01868
threonyl-tRNA synthetase [EC:
6.1.1.3
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00970
Aminoacyl-tRNA biosynthesis
Disease
H00866
Trichothiodystrophy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
00970 Aminoacyl-tRNA biosynthesis
6897 (TARS1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes [BR:
hsa01007
]
6897 (TARS1)
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis [BR:
hsa03016
]
6897 (TARS1)
Enzymes [BR:
hsa01000
]
6. Ligases
6.1 Forming carbon-oxygen bonds
6.1.1 Ligases forming aminoacyl-tRNA and related compounds
6.1.1.3 threonine---tRNA ligase
6897 (TARS1)
Amino acid related enzymes [BR:
hsa01007
]
Aminoacyl-tRNA synthetase
Class II (C/G)
6897 (TARS1)
Transfer RNA biogenesis [BR:
hsa03016
]
Eukaryotic type
Aminoacyl-tRNA synthetases (AARSs)
Other AARSs
6897 (TARS1)
Prokaryotic type
6897 (TARS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
tRNA-synt_2b
HGTP_anticodon
TGS
tRNA_SAD
Motif
Other DBs
NCBI-GeneID:
6897
NCBI-ProteinID:
NP_001245366
OMIM:
187790
HGNC:
11572
Ensembl:
ENSG00000113407
UniProt:
P26639
Structure
PDB
PDBj
LinkDB
All DBs
Position
5:33440696..33468091
Genome browser
AA seq
723 aa
AA seq
DB search
MFEEKASSPSGKMGGEEKPIGAGEEKQKEGGKKKNKEGSGDGGRAELNPWPEYIYTRLEM
YNILKAEHDSILAEKAEKDSKPIKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVIA
KVNNVVWDLDRPLEEDCTLELLKFEDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIE
NGFYYDMYLEEGGVSSNDFSSLEALCKKIIKEKQAFERLEVKKETLLAMFKYNKFKCRIL
NEKVNTPTTTVYRCGPLIDLCRGPHVRHTGKIKALKIHKNSSTYWEGKADMETLQRIYGI
SFPDPKMLKEWEKFQEEAKNRDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFI
RSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMF
DHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCL
DFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFY
GPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERM
IAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNK
KIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAE
EEF
NT seq
2172 nt
NT seq
+upstream
nt +downstream
nt
atgtttgaggagaaggccagcagtccttcagggaagatgggaggcgaggagaagccgatt
ggtgctggtgaagagaagcaaaaggaaggaggcaaaaagaagaacaaagaaggatctgga
gatggaggtcgagctgagttgaatccttggcctgaatatatttacacacgtcttgagatg
tataatatactaaaagcagaacatgattccattctggcagaaaaggcagaaaaagatagc
aagccaattaaagtcactttgcctgatggtaaacaggttgatgcggaatcttggaaaact
acaccatatcaaattgcctgtggaattagtcaaggcctggccgacaacaccgttattgct
aaagtaaataatgttgtgtgggacctggaccgccctctggaagaagattgtaccttggag
cttctcaagtttgaggatgaggaagctcaggcagtgtattggcactctagtgctcacata
atgggtgaagccatggaaagagtctatggtggatgtttatgctacggtccgccaatagaa
aatggattctattatgacatgtacctcgaagaagggggtgtgtctagcaatgatttctct
tctctggaggctttgtgtaagaaaatcattaaagaaaaacaagcttttgaaagactggaa
gttaagaaagaaactttactggcaatgtttaagtacaacaagttcaaatgccggatattg
aatgaaaaggtgaatactccaactaccacagtctatagatgtggccctttgatagatctc
tgccggggtcctcatgttagacacacgggcaaaattaaggctttaaaaatacacaaaaat
tcctccacgtactgggaaggcaaagcagatatggagactctccagagaatttatggcatt
tcattcccagatcctaaaatgttgaaagagtgggagaagttccaagaggaagctaaaaac
cgagatcataggaaaattggcagggaccaagaactatatttctttcatgaactcagccct
ggaagttgcttttttctgccaaaaggagcctacatttataatgcacttattgaattcatt
aggagcgaatataggaaaagaggattccaggaggtagtcaccccaaacatcttcaacagc
cgactctggatgacctcgggccactggcagcactacagcgagaacatgttctcctttgag
gtggagaaggagctgtttgccctgaaacccatgaactgcccaggacactgccttatgttt
gatcatcggccaaggtcctggcgagaactgcctctgcggctagctgattttggggtactt
cataggaacgagctgtctggagcactcacaggactcacccgggtacgaagattccaacag
gatgatgctcacatattctgtgccatggagcagattgaagatgaaataaaaggttgtttg
gattttctacgtacggtatatagcgtatttggattttcttttaaactaaacctttctact
cgcccggaaaaattccttggagatatcgaagtatgggatcaagctgagaaacaacttgaa
aacagtctgaatgaatttggtgaaaagtgggagttaaactctggagatggagctttctat
ggcccaaagattgacatacagattaaagatgcgattgggcggtaccaccagtgtgcaacc
atccagctggatttccagttgcccatcagatttaatcttacttatgtaagccatgatggt
gatgataagaaaaggccagtgattgttcatcgagccatcttgggatcagtggaaagaatg
attgctatcctcacagaaaactatgggggcaaatggcccttttggctgtcccctcgccag
gtaatggtagttccagtgggaccaacctgtgatgaatatgcccaaaaggtacgacaacaa
ttccacgatgccaaattcatggcagacattgatctggatccaggctgtacattgaataaa
aagattcgaaatgcacagttagcacagtataacttcattttagttgttggtgaaaaagag
aaaatcagtggcactgttaatatccgcacaagagacaataaggtccacggggaacgcacc
atttctgaaactatcgagcggctacagcagctcaaagagttccgcagcaaacaggcagaa
gaagaattttaa
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