Homo sapiens (human): 8313
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Entry
8313 CDS
T01001
Symbol
AXIN2, AXIL, ODCRCS
Name
(RefSeq) axin 2
KO
K04385
axin 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04310
Wnt signaling pathway
hsa04390
Hippo signaling pathway
hsa04550
Signaling pathways regulating pluripotency of stem cells
hsa04934
Cushing syndrome
hsa05010
Alzheimer disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05165
Human papillomavirus infection
hsa05200
Pathways in cancer
hsa05210
Colorectal cancer
hsa05213
Endometrial cancer
hsa05217
Basal cell carcinoma
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181
Salmonella
nt06215
WNT signaling (cancer)
nt06260
Colorectal cancer
nt06261
Gastric cancer
nt06263
Hepatocellular carcinoma
nt06270
Breast cancer
nt06271
Endometrial cancer
nt06274
Thyroid cancer
nt06505
WNT signaling
Element
N00056
Wnt signaling pathway
N00057
Mutation-inactivated APC to Wnt signaling pathway
N00058
Mutation-activated CTNNB1 to Wnt signaling pathway
N00059
FZD7-overexpression to Wnt signaling pathway
N00060
LRP6-overexpression to Wnt signaling pathway
Disease
H00020
Colorectal cancer
H00857
Oligodontia-colorectal cancer syndrome
H01667
Medulloblastoma
H02302
Hepatoblastoma
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
8313 (AXIN2)
04390 Hippo signaling pathway
8313 (AXIN2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
8313 (AXIN2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
8313 (AXIN2)
09162 Cancer: specific types
05210 Colorectal cancer
8313 (AXIN2)
05225 Hepatocellular carcinoma
8313 (AXIN2)
05226 Gastric cancer
8313 (AXIN2)
05217 Basal cell carcinoma
8313 (AXIN2)
05213 Endometrial cancer
8313 (AXIN2)
05224 Breast cancer
8313 (AXIN2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
8313 (AXIN2)
09164 Neurodegenerative disease
05010 Alzheimer disease
8313 (AXIN2)
05022 Pathways of neurodegeneration - multiple diseases
8313 (AXIN2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
8313 (AXIN2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
8313 (AXIN2)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Other centrosome associated proteins
8313 (AXIN2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS
DIX
AXIN1_TNKS_BD
Axin_b-cat_bind
DUF4827
DUF3005
Motif
Other DBs
NCBI-GeneID:
8313
NCBI-ProteinID:
NP_004646
OMIM:
604025
HGNC:
904
Ensembl:
ENSG00000168646
UniProt:
Q9Y2T1
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:complement(65528563..65561648)
Genome browser
AA seq
843 aa
AA seq
DB search
MSSAMLVTCLPDPSSSFREDAPRPPVPGEEGETPPCQPGVGKGQVTKPMPVSSNTRRNED
GLGEPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQM
NLKDTKTLRVAKAIYKRYIENNSIVSKQLKPATKTYIRDGIKKQQIDSIMFDQAQTEIQS
VMEENAYQMFLTSDIYLEYVRSGGENTAYMSNGGLGSLKVVCGYLPTLNEEEEWTCADFK
CKLSPTVVGLSSKTLRATASVRSTETVDSGYRSFKRSDPVNPYHIGSGYVFAPATSANDS
EISSDALTDDSMSMTDSSVDGIPPYRVGSKKQLQREMHRSVKANGQVSLPHFPRTHRLPK
EMTPVEPATFAAELISRLEKLKLELESRHSLEERLQQIREDEEREGSELTLNSREGAPTQ
HPLSLLPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHHHHHHSQYHSL
LPPGGKLPPAAASPGACPLLGGKGFVTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVH
CFCPGGSEYYCYSKCKSHSKAPETMPSEQFGGSRGSTLPKRNGKGTEPGLALPAREGGAP
GGAGALQLPREEGDRSQDVWQWMLESERQSKPKPHSAQSTKKAYPLESARSSPGERASRH
HLWGGNSGHPRTTPRAHLFTQDPAMPPLTPPNTLAQLEEACRRLAEVSKPPKQRCCVASQ
QRDRNHSATVQTGATPFSNPSLAPEDHKEPKKLAGVHALQASELVVTYFFCGEEIPYRRM
LKAQSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWEDETVLPMYEGRILGKVE
RID
NT seq
2532 nt
NT seq
+upstream
nt +downstream
nt
atgagtagcgctatgttggtgacttgcctcccggaccccagcagcagcttccgtgaggat
gccccgcggcccccagtgccaggggaagaaggggagaccccaccgtgtcagccaggggtg
ggcaagggccaggtcaccaaacccatgcctgtctcttccaacaccaggcggaacgaagat
gggttgggggagccggaggggcgggcatctccggattcccctctgacccggtggaccaag
tccttacactccttattgggcgatcaagacggtgcttacctgttccgaactttcctggag
agggagaaatgcgtggataccttagacttctggtttgcctgcaatggattcaggcagatg
aacctgaaggataccaaaactttacgagtagccaaagcgatctacaaaaggtacattgag
aacaacagcattgtctccaagcagctgaagcctgccaccaagacctacataagagatggc
atcaagaagcagcagattgattccatcatgtttgaccaggcgcagaccgagatccagtcg
gtgatggaggaaaatgcctaccagatgtttttgacttctgatatatacctcgaatatgtg
aggagtgggggagaaaacacagcttacatgagtaatgggggactcgggagcctaaaggtc
gtgtgtggctatctccccaccttgaatgaagaagaggagtggacttgtgccgacttcaag
tgcaaactttcgccaaccgtggttggcttgtccagcaaaactctgagggccacggcgagt
gtgaggtccacggaaactgttgacagtggatacaggtccttcaagaggagcgatcctgtt
aatccttatcacataggttctggctatgtctttgcaccagccaccagcgccaacgacagt
gagatatccagtgatgcgctgacggatgattccatgtccatgacggacagcagtgtagat
ggaattcctccttatcgtgtgggcagtaagaaacagctccagagagaaatgcatcgcagt
gtgaaggccaatggccaagtgtctctacctcatttcccgagaacccaccgcctgcccaag
gagatgacccccgtggaacccgccacctttgcagctgagctgatctcgaggctggaaaag
ctgaagctggagttggagagccgccacagcctggaggagcgcctgcagcagatccgagag
gatgaagagagagagggctccgagctcacactcaattcgcgggagggggcgcccacgcag
caccccctctccctactgccctccggcagctacgaggaagacccgcagacgatactggac
gatcacctgtccagggtcctcaagacccctggctgccagtctccaggcgtaggccgctat
agcccccgctcccgctccccggaccaccaccaccaccaccattcgcagtaccactccctg
ctcccgcccggtggcaagctgcctcccgcggccgcctcgccgggcgcctgccccctcctc
gggggcaaaggctttgtgaccaagcagacgacgaagcatgtccaccaccactacatccac
caccatgccgtccccaagaccaaggaggagatcgaggcggaggccacgcagcgggtgcac
tgcttctgccctgggggcagcgagtattactgctactcgaaatgcaaaagccactccaag
gctccggaaaccatgcccagcgagcagtttggcggcagcagaggcagtaccttgcccaaa
cgcaatgggaaaggcacggagccgggcctggccctgcccgccagggaaggaggggccccc
ggcggagctggggccctgcagcttccccgggaggaaggagacaggtcgcaggatgtctgg
cagtggatgctggagagtgagcggcagagcaagcccaagccccatagtgcccaaagcaca
aaaaaggcctaccccttggagtctgcccgctcgtctccaggcgaacgagccagccggcac
catctgtgggggggcaacagcgggcacccccgcaccaccccccgtgcccacctgttcacc
caggaccctgcgatgcctcccctgaccccacccaacacgctggctcagctggaggaggcc
tgtcgcaggctagctgaggtgtcgaagcccccaaagcagcggtgctgtgtggccagtcag
cagagggacaggaatcattcggccactgttcagacgggagccacacccttctccaatcca
agcctggctccagaagatcacaaagagccaaagaaactggcaggtgtccacgcgctccag
gccagtgagttggttgtcacttactttttctgtggggaagaaattccataccggaggatg
ctgaaggctcagagcttgaccctgggccactttaaagagcagctcagcaaaaagggaaat
tataggtattacttcaaaaaagcaagcgatgagtttgcctgtggagcggtgtttgaggag
atctgggaggatgagacggtgctcccgatgtatgaaggccggattctgggcaaagtggag
cggatcgattga
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